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Article
Plasma Apo-E mediated corticospinal tract abnormalities and suicidality in patients with major depressive disorder
This study aims to explore the link between Apo-E, brain white matter, and suicide in patients with major depressive disorder (MDD) to investigate the potential neuroimmune mechanisms of Apo-E that may lead to...
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Article
Open AccessLong-Term Stimulation of the Left Dorsal Branch of the Thoracic Nerve Improves Ventricular Electrical Remodeling in a Canine Model of Chronic Myocardial Infarction
To evaluate the ventricular electrophysiologic effects of long-term stimulation of the left dorsal branch of thoracic nerve (LDTN) derived from the left stellate ganglion (LSG) in a canine model of chronic myo...
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Article
Open AccessCircular RNA HSDL2 promotes breast cancer progression via miR-7978 ZNF704 axis and regulating hippo signaling pathway
Circular RNAs (circRNAs) are a new group of endogenous RNAs recently found to be involved in the development of various diseases, including their confirmed involvement in the progression of several types of ca...
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Article
Open AccessPostoperative complications and axial length growth after bilateral congenital cataract surgery: eyes with microphthalmos compared to a comparison group
To investigate the postoperative clinical outcomes and axial length (AL) growth of infants with congenital cataracts and microphthalmos following first-stage cataract surgery.
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Article
Cyber-Physical System Converged Digital Twin for Secure Patient Monitoring and Attack Detection
A live or non-living object’s digital twin is its mirror image. Businesses, particularly in the healthcare sector, are entering a new era thanks to digital twins and cyber-physical systems (CPS), which collect...
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Article
Open AccessMETTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4
N6-methyladenosine (m6A) is the predominant post-transcriptional RNA modification in eukaryotes and plays a pivotal regulatory role in various aspects of RNA fate determination, such as mRNA stability, alternativ...
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Article
Open AccessSegregation of endosymbionts in complex symbiotic system of cicadas providing novel insights into microbial symbioses and evolutionary dynamics of symbiotic organs in sap-feeding insects
The most extraordinary systems of symbiosis in insects are found in the suborder Auchenorrhyncha of Hemiptera, which provide unique perspectives for uncovering complicated insect-microbe symbiosis. We investig...
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Article
Open AccessThymoquinone as an electron transfer mediator to convert Type II photosensitizers to Type I photosensitizers
The development of Type I photosensitizers (PSs) is of great importance due to the inherent hypoxic intolerance of photodynamic therapy (PDT) in the hypoxic microenvironment. Compared to Type II PSs, Type I PS...
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Article
Long-Term Outcomes Following Freehand Minimally Invasive Aspiration for Deep Supratentorial Intracerebral Hemorrhage: A Multicenter Cohort Study
The aim of this study was to compare the therapeutic effects of non-navigated freehand minimally invasive aspiration and conservative medical care in patients with deep supratentorial intracerebral hemorrhage ...
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Article
Open AccessDynamic Changes of Capsular-Intraocular Lens Adhesion in Plate-Haptic Hydrophilic and Loop-Haptic Hydrophobic Eyes
The aim of this work is to investigate the dynamic changes of capsular-intraocular lens (IOL) adhesion in plate-haptic hydrophilic and loop-haptic hydrophobic eyes.
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Article
Selective depolymerization of lignin into phenolic products over NixZn1 − x/ZrO2-MgO
The achievement of valuable utilization of lignin will greatly alleviate the energy crisis. In this study, a series of supported bimetallic catalysts (NixZn1−x/ZrO2-MgO) were prepared and their physicochemical pr...
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Article
Open AccessDomain wall magnetic tunnel junction-based artificial synapses and neurons for all-spin neuromorphic hardware
We report a breakthrough in the hardware implementation of energy-efficient all-spin synapse and neuron devices for highly scalable integrated neuromorphic circuits. Our work demonstrates the successful execut...
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Article
Immune profiling analysis of double-negative T cells in patients with systemic sclerosis
To construct a molecular immune map of patients with systemic sclerosis (SSc) by mass flow cytometry, and compare the number and molecular expression of double-negative T (DNT) cell subsets between patients an...
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Article
Iterative unsupervised deep bilateral texture filtering
Texture filtering attempts to retain salient structures and remove insignificant textures. In this paper, we propose a highly effective iterative unsupervised deep bilateral texture filtering neural network fo...
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Article
Open AccessPotential of niacin skin flush response in adolescent depression identification and severity assessment: a case-control study
The diagnosis of adolescent Depressive Disorder (DD) lacks specific biomarkers, posing significant challenges. This study investigates the potential of Niacin Skin Flush Response (NSFR) as a biomarker for iden...
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Article
Open AccessCell membrane vesicles derived from hBMSCs and hUVECs enhance bone regeneration
Bone tissue renewal can be enhanced through co-transplantation of bone mesenchymal stem cells (BMSCs) and vascular endothelial cells (ECs). However, there are apparent limitations in stem cell-based therapy wh...
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Article
In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential
Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea and high mortality in neonatal suckling piglets, leading to significant economic losses to the swine industry. Panax notoginseng saponins (PNS) are bi...
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Article
Open AccessA negative feedback loop between TET2 and leptin in adipocyte regulates body weight
Ten-eleven translocation (TET) 2 is an enzyme that catalyzes DNA demethylation to regulate gene expression by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine, functioning as an essential epigenetic regul...
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Article
Biodeterioration of polyethylene by Bacillus cereus and Rhodococcus equi isolated from soil
Polyethylene (PE), a non-biodegradable plastic, is widely used in agriculture as a mulch material, which causes serious plastic pollution when it is discarded. Recent studies have described the biodeterioratio...
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Article
Umbilical cord mesenchymal stem cells transplantation in patients with systemic sclerosis: a 5-year follow-up study
To assess the long-term safety and efficacy of umbilical cord mesenchymal stem cells transplantation (UMSCT) in patients with systemic sclerosis (SSc).
