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    Article

    Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2

    Dai Zhang and colleagues report a genome-wide association study for schizophrenia in the Han Chinese population. They identify a new susceptibility locus at 11p11.2 and also identify a locus at 6p21-22.1 in th...

    Wei-Hua Yue, Hai-Feng Wang, Liang-Dan Sun, Fu-Lei Tang, Zhong-Hua Liu in Nature Genetics (2011)

  2. No Access

    Article

    Joint analysis of three genome-wide association studies of esophageal squamous cell carcinoma in Chinese populations

    Dongxin Lin, Philip Taylor, Li-Dong Wang and colleagues have now pooled three genome-wide association analyses of esophageal squamous cell carcinoma, finding two new risk loci at genome-wide significance and a...

    Chen Wu, Zhaoming Wang, **n Song, **ao-Shan Feng, Christian C Abnet in Nature Genetics (2014)

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    Article

    Long noncoding RNA MALAT1 suppresses breast cancer metastasis

    MALAT1 has previously been described as a metastasis-promoting long noncoding RNA (lncRNA). We show here, however, that targeted inactivation of the Malat1 gene in a transgenic mouse model of breast cancer, witho...

    Jongchan Kim, Hai-Long Piao, Beom-Jun Kim, Fan Yao, Zhenbo Han in Nature Genetics (2018)

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    Article

    Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the...

    Anubha Mahajan, Cassandra N. Spracklen, Weihua Zhang, Maggie C. Y. Ng in Nature Genetics (2022)

  5. No Access

    Article

    Genomic innovation and regulatory rewiring during evolution of the cotton genus Gossypium

    Phenotypic diversity and evolutionary innovation ultimately trace to variation in genomic sequence and rewiring of regulatory networks. Here, we constructed a pan-genome of the Gossypium genus using ten represent...

    Maojun Wang, Jianying Li, Zhengyang Qi, Yuexuan Long, Liuling Pei in Nature Genetics (2022)

  6. Article

    Open Access

    Genome assemblies of 11 bamboo species highlight diversification induced by dynamic subgenome dominance

    Polyploidy (genome duplication) is a pivotal force in evolution. However, the interactions between parental genomes in a polyploid nucleus, frequently involving subgenome dominance, are poorly understood. Here...

    Peng-Fei Ma, Yun-Long Liu, Cen Guo, Guihua **, Zhen-Hua Guo, Ling Mao in Nature Genetics (2024)