102 Result(s)

Article

Revealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression

The human brain has been implicated in the pathogenesis of several complex diseases. Taking advantage of single-cell techniques, genome-wide association studies (GWAS) have taken it a step further and revealed...

Ruo-Han Hao, Tian-Pei Zhang, Feng Jiang, Jun-Hui Liu… in Nature Communications (2024)

Article

PD-1/CD80⁺ small extracellular vesicles from immunocytes induce cold tumours featured with enhanced adaptive immunosuppression

Only a minority of cancer patients benefit from immune checkpoint blockade therapy. Sophisticated cross-talk among different immune checkpoint pathways as well as interaction pattern of immune checkpoint molec...

Lin-Zhou Zhang, Jie-Gang Yang, Gai-Li Chen, Qi-Hui **e, Qiu-Yun Fu… in Nature Communications (2024)

Article

Global fungal-host interactome map** identifies host targets of candidalysin

Candidalysin, a cytolytic peptide toxin secreted by the human fungal pathogen Candida albicans, is critical for fungal pathogenesis. Yet, its intracellular targets have not been extensively mapped. Here, we perfo...

Tian-Yi Zhang, Yao-Qi Chen, **g-Cong Tan, **-An Zhou… in Nature Communications (2024)

Article

Dynamic root microbiome sustains soybean productivity under unbalanced fertilization

Root-associated microbiomes contribute to plant growth and health, and are dynamically affected by plant development and changes in the soil environment. However, how different fertilizer regimes affect quanti...

Mingxing Wang, An-Hui Ge, **ngzhu Ma, **aolin Wang, Qiu** **e… in Nature Communications (2024)

Article

Camrelizumab and apatinib plus induction chemotherapy and concurrent chemoradiotherapy in stage N3 nasopharyngeal carcinoma: a phase 2 clinical trial

The antiangiogenic agent apatinib has been shown to clinically improve responses to immune checkpoint inhibitors in several cancer types. Patients with N3 nasopharyngeal carcinoma have a high risk of distant m...

Hu Liang, Yao-Fei Jiang, Guo-Ying Liu, Lin Wang, Jian-Wei Wang… in Nature Communications (2024)

Article

Addendum: Cellular differentiation into hyphae and spores in halophilic archaea

Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova… in Nature Communications (2024)

Article

Electrical tuning of branched flow of light

Branched flows occur ubiquitously in various wave systems, when the propagating waves encounter weak correlated scattering potentials. Here we report the experimental realization of electrical tuning of the br...

Shan-shan Chang, Ke-Hui Wu, Si-jia Liu, Zhi-Kang Lin, **-bing Wu… in Nature Communications (2024)

Article

Intranasal mask for protecting the respiratory tract against viral aerosols

The spread of many infectious diseases relies on aerosol transmission to the respiratory tract. Here we design an intranasal mask comprising a positively-charged thermosensitive hydrogel and cell-derived micro...

**aoming Hu, Shuang Wang, Shaotong Fu, Meng Qin, Chengliang Lyu… in Nature Communications (2023)

Article

Diploid and tetraploid genomes of Acorus and the evolution of monocots

Monocots are a major taxon within flowering plants, have unique morphological traits, and show an extraordinary diversity in lifestyle. To improve our understanding of monocot origin and evolution, we generate...

Liang Ma, Ke-Wei Liu, Zhen Li, Yu-Yun Hsiao, Yiying Qi, Tao Fu… in Nature Communications (2023)

Article

Structure and proposed DNA delivery mechanism of a marine roseophage

Tailed bacteriophages (order, Caudovirales) account for the majority of all phages. However, the long flexible tail of siphophages hinders comprehensive investigation of the mechanism of viral gene delivery. Here...

Yang Huang, Hui Sun, Shuzhen Wei, Lanlan Cai, Liqin Liu… in Nature Communications (2023)

Article

Renal denervation reverses ventricular structural and functional remodeling in failing rabbit hearts

Renal denervation (RDN) suppresses the activity of the renin–angiotensin–aldosterone system and inflammatory cytokines, leading to the prevention of cardiac remodeling. Limited studies have reported the effect...

Ting-Chun Huang, Li-Wei Lo, Yu-Hui Chou, Wei-Lun Lin, Shih-Lin Chang… in Scientific Reports (2023)

Article

Self-wavelength shifting in two-dimensional perovskite for sensitive and fast gamma-ray detection

Lead halide perovskites have recently emerged as promising X/γ-ray scintillators. However, the small Stokes shift of exciton luminescence in perovskite scintillators creates problems for the light extraction e...

Tong **, Zheng Liu, Jiajun Luo, Jun-Hui Yuan, Hanqi Wang… in Nature Communications (2023)

Article

A randomized trial of Trendelenburg position for acute moderate ischemic stroke

We aim to explore the effect of head-down position (HDP), initiated within 24 hours of onset, in moderate anterior circulation stroke patients with probable large artery atherosclerosis (LAA) etiology. This in...

Hui-Sheng Chen, Nan-Nan Zhang, Yu Cui, **ao-Qiu Li, Cheng-Shu Zhou… in Nature Communications (2023)

Article

Cellular differentiation into hyphae and spores in halophilic archaea

Several groups of bacteria have complex life cycles involving cellular differentiation and multicellular structures. For example, actinobacteria of the genus Streptomyces form multicellular vegetative hyphae, aer...

Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova… in Nature Communications (2023)

Article

Lamella-heterostructured nanoporous bimetallic iron-cobalt alloy/oxyhydroxide and cerium oxynitride electrodes as stable catalysts for oxygen evolution

Develo** robust nonprecious-metal electrocatalysts with high activity towards sluggish oxygen-evolution reaction is paramount for large-scale hydrogen production via electrochemical water splitting. Here we ...

Shu-Pei Zeng, Hang Shi, Tian-Yi Dai, Yang Liu, Zi Wen… in Nature Communications (2023)

Article

Limitations of gene editing assessments in human preimplantation embryos

Range of DNA repair in response to double-strand breaks induced in human preimplantation embryos remains uncertain due to the complexity of analyzing single- or few-cell samples. Sequencing of such minute DNA ...

Dan Liang, Aleksei Mikhalchenko, Hong Ma, Nuria Marti Gutierrez… in Nature Communications (2023)

Article

Tracking westerly wind directions over Europe since the middle Holocene

The variability of the northern westerlies has been considered as one of the key elements for modern and past climate evolution. Their multiscale behavior and underlying control mechanisms, however, are incomp...

Hsun-Ming Hu, Valerie Trouet, Christoph Spötl, Hsien-Chen Tsai… in Nature Communications (2022)

Article

A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain

The effectiveness of a 3^rd dose of SARS-CoV-2 vaccines waned quickly in the Omicron-predominant period. In response to fast-waning immunity and the threat of Omicron variant of concern (VOC) to healthcare workers...

Ji Wang, Caiguangxi Deng, Ming Liu, Yihao Liu, Liubing Li… in Nature Communications (2022)

Article

The gut microbe Bacteroides fragilis ameliorates renal fibrosis in mice

Renal fibrosis is an inevitable outcome of various manifestations of progressive chronic kidney diseases (CKD). The need for efficacious treatment regimen against renal fibrosis can therefore not be overemphas...

Wei Zhou, Wen-hui Wu, Zi-lin Si, Hui-ling Liu, Hanyu Wang… in Nature Communications (2022)