477,568 Result(s)
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Medicine & Public Health
Internal Medicine
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Article
Open AccessMolecular circadian clock disruption in the leukocytes of individuals with type 2 diabetes and overweight, and its relationship with leukocyte–endothelial interactions
Alterations in circadian rhythms increase the likelihood of develo** type 2 diabetes and CVD. Circadian rhythms are controlled by several core clock genes, which are expressed in nearly every cell, including...
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Open AccessProsaposin hyperglycosylation: a novel tumor immune escape mechanism and implications for cancer immunotherapy
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Open AccessExtraskeletal osteosarcoma infiltrating pancreas, spleen, gastric, and left kidney: a case report
Extraskeletal osteosarcoma is an extremely rare malignancy that accounts for 1% of soft tissue sarcoma and 4.3% of all osteosarcoma. Extraskeletal osteosarcoma can develop in a patient between the ages of 48 a...
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Extrakorporale Erregerelimination mit biomimetischem Adsorber – eine neue Therapiestrategie für die Intensivmedizin
Die Weltgesundheitsorganisation (World Health Organization [WHO]) erklärte im Jahre 2019 die antimikrobielle Resistenz zu einer der zehn größten globalen Bedrohungen für die öffentliche Gesundheit. Im gleichen...
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Open AccessCentral nervous system involvement in chronic lymphocytic leukemia: a case report and review of literature
Central nervous system involvement in chronic lymphocytic leukemia rarely occurs, and there is no standard therapy for central nervous system involvement in chronic lymphocytic leukemia. This article aims to a...
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Open AccessHigh-resolution and highly accelerated MRI T2 map** as a tool to characterise renal tumour subtypes and grades
Clinical imaging tools to probe aggressiveness of renal masses are lacking, and T2-weighted imaging as an integral part of magnetic resonance imaging protocol only provides qualitative information. We develope...
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Open AccessZinc fever in a painter and varnisher: a case report
Zinc fever is well described in medical literature, particularly in workers after handling zinc-containing materials at high temperatures e.g., in the welding of hot-dip galvanized steel sheets. It is not know...
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The Association of Gabapentin Initiation with Cognitive and Behavioral Changes in Older Adults with Cognitive Impairment: A Retrospective Cohort Study
Although gabapentin has been increasingly prescribed to older adults, the relation between gabapentin initiation and longer-term neurocognitive changes is not well understood. Thus, this study aimed to examine...
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Open AccessPrevalence of key potentially inappropriate drugs use in pediatrics: a cross-sectional study
Appropriate drug prescribing in the pediatric population is challenging, given this age group’s unique pharmacokinetics. This has inevitably led to a high incidence of adverse drug reactions in this population...
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Open AccessSupporting Care Transformation Through a Comprehensive Graduate Medical Education Curricular Program in a Department of Internal Medicine
The imperative to train physicians in skills required to lead care transformation is increasingly recognized, yet few Graduate Medical Education (GME) programs exist to meet this need.
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Open AccessNovel associations between MTDH gene polymorphisms and invasive ductal breast cancer: a case–control study
To reveal the contributing effects of MTDH gene SNPs in the risk of invasive ductal breast cancer (IDC).
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Open AccessThe relationship between uric acid and bone mineral density in the intermediate stage of CKD 1–3
Some studies have suggested that uric acid has antioxidant properties that can prevent bone loss, but the relationship between uric acid and bone mineral density is controversial. The aim of this study was to ...
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Open AccessCan geroscience be translated into healthcare?
As an introduction to this special issue on geroscience, the present work focuses on the complexity of disentangling biomolecular mechanisms of aging from biopsychosocial causes of accelerated aging. Due to th...
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Article
Open AccessInvolvement of Kindlin-1 in cutaneous squamous cell carcinoma
Kindler syndrome (KS) is a rare genodermatosis resulting from loss-of-function mutations in FERMT1, the gene that encodes Kindlin-1. KS patients have a high propensity to develop aggressive and metastatic cutaneo...
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Association between hematological indices and blood glucose level among patients with type 2 diabetes
Diabetes mellitus is a major health problem with a variety of implications: cellular, metabolic, and hematological. Hematological alterations observed in type 2 diabetes are related to hyperglycemia and have a...
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Article
The evolving landscape of autoimmune hepatitis: an ambispective cohort study
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Open AccessSkin carotenoid scores and metabolic syndrome in a general Japanese population: the Hisayama study
Higher vegetable intake is being promoted as an initiative to prevent lifestyle-related diseases. Carotenoids are yellow or red pigment components and are widely present in vegetables. Since ingested carotenoi...
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Open AccessMR radiomics to predict microvascular invasion status and biological process in combined hepatocellular carcinoma-cholangiocarcinoma
To establish an MRI-based radiomics model for predicting the microvascular invasion (MVI) status of cHCC-CCA and to investigate biological processes underlying the radiomics model.
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Open AccessAssessment of three criteria to establish borrelial infection in suspected lyme neuroborreliosis
Diagnosis of (European) Lyme neuroborreliosis has been based on clinical presentation, cerebrospinal fluid (CSF) pleocytosis and demonstration of intrathecal borrelial antibody synthesis (ITBAS) to document Borre...
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Open AccessDermotoscope assisted diagnosis of adolescent bullous pilomatricoma: six case reports
Pilomatricoma (PM) is a cutaneous benign neoplasm derived from the hair matrix. It clinically presents as a solitary and firm nodule overlying normal epidermis and is usually not easy to be noticed at early st...
