2,488 Result(s)
within
**n Shou
-
Article
Open Access4-1BB-encoding CAR causes cell death via sequestration of the ubiquitin-modifying enzyme A20
CD28 and 4-1BB costimulatory endodomains included in chimeric antigen receptor (CAR) molecules play a critical role in promoting sustained antitumor activity of CAR-T cells. However, the molecular events assoc...
-
Article
An Investigation on the Thermal and Antibacterial Properties and Comprehensive Performance of New Graphene Knitted Fabrics
This paper investigates the new graphene fibre primary performance, taking the winter multifunctional knitted fabric with heat and antibacterial as the starting point. Using 150D graphene yarn, ordinary polyes...
-
Article
Open Access0.75% ropivacaine may be a suitable drug in pregnant women undergoing urgent cesarean delivery during labor analgesia period
3% chloroprocaine (CP) has been reported as the common local anesthetic used in pregnant women undergoing urgent cesarean delivery during labor analgesia period. However, 0.75% ropivacaine is considered a prom...
-
Article
Prenatal Inflammatory Exposure Predisposes Offspring to Chronic Kidney Diseases Via the Activation of the eIF2α-ATF4 Pathway
It has recently become more recognized that renal diseases in adults can originate from adverse intrauterine (maternal) environmental exposures. Previously, we found that prenatal lipopolysaccharide (LPS) expo...
-
Article
Non-Canonical STING-PERK Pathway Modulation of Cellular Senescence and Therapeutic Response in Sepsis-Associated Acute Kidney Injury
Abstract–This study explored the role of the non-canonical STING-PERK signaling pathway in sepsis-associated acute kidney injury (SA-AKI). Gene expression data from the GEO database and serum STING protein levels...
-
Article
Open AccessComparative transcriptomic and proteomic kinetic analysis of adeno-associated virus production systems
Recombinant adeno-associated virus (rAAV) is a major gene delivery vehicle. We have constructed a stable rAAV producer cell line by integrating essential rAAV genome, viral and helper genes into the genome of ...
-
Article
Open AccessLiouville irregular states of half-integer ranks
We conjecture a set of differential equations that characterizes the Liouville irregular states of half-integer ranks, which extends the generalized AGT correspondence to all the (A1, Aeven) and (A1, Dodd) types ...
-
Article
Open AccessNanomaterials-assisted gene editing and synthetic biology for optimizing the treatment of pulmonary diseases
The use of nanomaterials in gene editing and synthetic biology has emerged as a pivotal strategy in the pursuit of refined treatment methodologies for pulmonary disorders. This review discusses the utilization...
-
Article
Possibilities for the synthesis of superheavy element \(Z=121\) in fusion reactions
Based on the dinuclear system model, the calculated evaporation residue cross sections matched well with the current experimental results. The synthesis of superheavy elements
-
Article
Open AccessmiRNA-seq analysis of high glucose induced osteoblasts provides insight into the mechanism underlying diabetic osteoporosis
The present study aims to explore the etiology of Diabetic osteoporosis (DOP), a chronic complication associated with diabetes mellitus. Specifically, the research seeks to identify potential miRNA biomarkers ...
-
Article
Development and Evaluation on Thermoregulating Slee** Bags with Phase Change Viscose Fiber
Slee** bag can protect the human body kee** warm effectively in the cold environment. Among the many varieties slee** bags, phase change thermoregulating slee** bag is an innovative product, which can ...
-
Article
MSNSegNet: attention-based multi-shape nuclei instance segmentation in histopathology images
In clinical research, the segmentation of irregularly shaped nuclei, particularly in mesenchymal areas like fibroblasts, is crucial yet often neglected. These irregular nuclei are significant for assessing tis...
-
Article
A novel digital extraction approach of pore network models from carbonates inspired by quantum genetic optimization techniques
Estimating hydraulic properties of carbonate is challenging due to its wider range of porosity and complex pore structures. To investigate the hydraulic properties of carbonate rocks, a novel approach inspired...
-
Article
Open AccessFL-GUARD: A Holistic Framework for Run-Time Detection and Recovery of Negative Federated Learning
Federated learning (FL) is a promising approach for learning a model from data distributed on massive clients without exposing data privacy. It works effectively in the ideal federation where clients share hom...
-
Article
Trabecular bone mineral density as measured by thoracic vertebrae predicts incident hip and vertebral fractures: the multi-ethnic study of atherosclerosis
We evaluated the relationship of bone mineral density (BMD) by computed tomography (CT), to predict fractures in a multi-ethnic population. We demonstrated that vertebral and hip fractures were more likely in ...
-
Article
How Do Foreign SMEs Mitigate Violent Conflict Risk by Doing Good? An Instrumental Stakeholder Theory Perspective
Large foreign firms’ interventions in violent conflicts have drawn increasing research attention. Nonetheless, scant research has investigated how foreign small and medium-sized enterprises (SMEs), which have ...
-
Article
CT features combined with RECIST 1.1 criteria improve progression assessments of sunitinib-treated gastrointestinal stromal tumors
To explore the auxiliary value of combining CT features with existing response evaluation criteria in the prediction of progressive disease (PD) in gastrointestinal stromal tumors (GIST) patients treated with ...
-
Article
Open AccessEffect of cervical Bishop score on induction of labor at term in primiparas using Foley catheter balloon: a retrospective study
Previous studies had found that the mechanical methods were as effective as pharmacological methods in achieving vaginal delivery. However, whether balloon catheter induction is suitable for women with severe ...
-
Article
Machine Learning from Veno-Venous Extracorporeal Membrane Oxygenation Identifies Factors Associated with Neurological Outcomes
Neurological complications are common in patients receiving veno-venous extracorporeal membrane oxygenation (VV-ECMO) support. We used machine learning (ML) algorithms to identify predictors for neurological o...
-
Article
A Characterization of Graphs with Semitotal Domination Number One-Third Their Order
In an isolate-free graph G, a subset S of vertices is a semitotal dominating set of G if it is a dominating set of G and every vertex in S is within distance 2 of another vertex of S. The semitotal domination num...
