32 Result(s)

Article

Assessment of subclinical LV myocardial dysfunction in T2DM patients with diabetic peripheral neuropathy: a cardiovascular magnetic resonance study

Diabetic peripheral neuropathy (DPN) is the most prevalent complication of diabetes, and has been demonstrated to be independently associated with cardiovascular events and mortality. This aim of this study wa...

Xue-Ming Li, Ke Shi, Li Jiang, **g Wang, Wei-Feng Yan… in Cardiovascular Diabetology (2024)

Article

The Characteristics of the Influenza Virus Epidemic Around the SARS-CoV-2 Epidemic Period in the Pudong New Area of Shanghai

The concurrent impact of COVID-19 and influenza on disease burden is a topic of great concern. This discussion delves into the epidemiological characteristics of seasonal influenza activity in Shanghai within ...

Ge Zhang, Anran Zhang, Li Zhang, Aiqin Zhu… in Journal of Epidemiology and Global Health (2024)

Article

Physical frailty intensifies the positive association of oral frailty with poor global cognitive function and executive function among older adults especially for females: a cross-sectional study

Oral frailty is reported to increase the risk of new onset of mild cognitive impairment. Whereas, the association of oral frailty with cognition among older adults in both physical frail and non-physical frail...

Yang Fei, Shuzhen Niu, Xueru **, Wen** Tang, Yue Zhao, Ge Zhang… in BMC Geriatrics (2024)

Article

Glycemic control and clinical outcomes in diabetic patients with heart failure and reduced ejection fraction: insight from ventricular remodeling using cardiac MRI

Glycemic control, as measured by glycosylated hemoglobin (HbA1c), is an important biomarker to evaluate diabetes severity and is believed to be associated with heart failure development. Type 2 diabetes mellit...

Ke Shi, Ge Zhang, Hang Fu, Xue-Ming Li, Yue Gao, Rui Shi… in Cardiovascular Diabetology (2024)

Article

Abnormalities of retinal function in type 2 diabetes mellitus patients without clinical diabetic retinopathy detected by multifocal electroretinogram

To study the changes of retinal function in type 2 diabetes mellitus(DM) patients without apparently diabetic retinopathy via multifocal electroretinogram. Methods: Thirty-six type 2 DM patients (72 eyes) with...

Rong-Rong Li, Yang Yang, Meng-Ge Zhang, Jie Wang, Hong Chen, Shan Liu… in BMC Ophthalmology (2024)

Article

Reduced thoracic skeletal muscle size is associated with adverse outcomes in diabetes patients with heart failure and reduced ejection fraction: quantitative analysis of sarcopenia by using cardiac MRI

Sarcopenia is frequently found in patients with heart failure with reduced ejection fraction (HFrEF) and is associated with reduced exercise capacity, poor quality of life and adverse outcomes. Recent evidence...

Ke Shi, Ge Zhang, Hang Fu, Xue-Ming Li, Shi-Qin Yu, Rui Shi… in Cardiovascular Diabetology (2024)

Article

Association of insulin use with LV remodeling and clinical outcomes in diabetic patients with heart failure and reduced ejection fraction: assessed by cardiac MRI

Insulin is commonly used in type 2 diabetes mellitus (T2DM) to achieve glycemic control. However, recent evidence showed that insulin use is associated with poor outcomes in the context of heart failure (HF). ...

Ke Shi, Ge Zhang, Hang Fu, Shan Huang, Hua-Yan Xu, Yue Gao… in Cardiovascular Diabetology (2023)

Article

A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth

Preterm birth (PTB), defined as delivery before 37 gestational weeks, imposes significant public health burdens. A recent maternal genome-wide association study of spontaneous PTB identified a noncoding locus ...

Li Wang, Robert M. Rossi, **aoting Chen, **g Chen, Jilian Runyon… in BMC Medicine (2023)

Article

Reducing the incidence of stroke-associated pneumonia: an evidence-based practice

Pulmonary infection is a frequent complication among stroke patients and adversely affects clinical outcomes, increases the length of hospitalization stay and costs, and aggravates the financial burden of the ...

Zhu-Yun Liu, Lin Wei, Ri-Chun Ye, Jiao Chen, Dan Nie, Ge Zhang… in BMC Neurology (2022)

Article

Reproducibility and feasibility of optic nerve diffusion MRI techniques: single-shot echo-planar imaging (EPI), readout-segmented EPI, and reduced field-of-view diffusion-weighted imaging

Diffusion-weighted imaging (DWI) is an essential technique for optic nerve diseases. However, the image quality of optic nerve DWI is decreased by the distortions and artifacts associated with conventional tec...

Fanglu Zhou, Qing Li, **aohui Zhang, Hongli Ma, Ge Zhang, Silin Du… in BMC Medical Imaging (2022)

Article

Recombinant human erythropoietin ameliorates cognitive dysfunction of APP/PS1 mice by attenuating neuron apoptosis via HSP90β

Hua-Li Wan, Bing-Ge Zhang, Chongyang Chen… in Signal Transduction and Targeted Therapy (2022)

Article

Effects of diabetes mellitus on left ventricular function and remodeling in hypertensive patients with heart failure with reduced ejection fraction: assessment with 3.0 T MRI feature tracking

Heart failure with reduced ejection fraction (HFrEF) is a major health burden worldwide with high morbidity and mortality. Comorbidities of HFrEF complicate treatment and lead to poor prognosis, among which hy...

Ge Zhang, Ke Shi, Wei-Feng Yan, Xue-Ming Li, Yuan Li… in Cardiovascular Diabetology (2022)

Article

Learning to predict in-hospital mortality risk in the intensive care unit with attention-based temporal convolution network

Dynamic prediction of patient mortality risk in the ICU with time series data is limited due to high dimensionality, uncertainty in sampling intervals, and other issues. A new deep learning method, temporal co...

Yu-wen Chen, Yu-jie Li, Peng Deng, Zhi-yong Yang, Kun-hua Zhong… in BMC Anesthesiology (2022)

Article

Neurological and psychiatric presentations associated with COVID-19

The objective is to investigate coronavirus disease 2019 (COVID-19)-associated neurological and psychiatric effects and explore possible pathogenic mechanisms. This study included 77 patients with laboratory-c...

Xudong He, Dan Zhang, Lei Zhang, Xu Zheng… in European Archives of Psychiatry and Clinic… (2022)

Article

The role of Sphingomyelin synthase 2 (SMS2) in platelet activation and its clinical significance

Sphingomyelin (SM) is an essential component of biological lipid rafts, and it plays an indispensable role in maintaining plasma membrane stability and in mediating signal transduction. The ultimate biosynthes...

Yifan Guo, Lin Chang, Ge Zhang, Zhanyan Gao, Hao Lin, Yuting Zhang… in Thrombosis Journal (2021)

Article

Trans-scapular approach coil localization for scapular-blocked pulmonary nodules: a retrospective study

Preoperative computed tomography (CT)-guided coil localization (CL) is commonly used to facilitate video-assisted thoracoscopic surgery (VATS)-guided diagnostic wedge resection (WR) of pulmonary nodules (PNs)....

Juan Wu, Min-Ge Zhang, ** Chen, Wen-Bin Ji in Journal of Cardiothoracic Surgery (2021)

Article

STAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17

In tauopathies, memory impairment positively strongly correlates with the amount of abnormal tau aggregates; however, how tau accumulation induces synapse impairment is unclear. Recently, we found that human t...

**ao-Yue Hong, Hua-Li Wan, Ting Li… in Signal Transduction and Targeted Therapy (2020)

Article

Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice

In vertebrates, the type 1 parathyroid hormone receptor (PTH1R) is a critical regulator of skeletal development and homeostasis; however, how it is modulated is incompletely understood. Here we report that del...

Xuekun Fu, Bo Zhou, Qinnan Yan, Chu Tao… in Signal Transduction and Targeted Therapy (2020)

Article

Efficacy of closed reduction for developmental dysplasia of the hip: midterm outcomes and risk factors associated with treatment failure and avascular necrosis

The purpose of this study was to evaluate the efficacy of closed reduction (CR) in the treatment of developmental dysplasia of the hip (DDH) and to investigate risk factors associated with CR failure and avasc...

Ge Zhang, Ming Li, **angyang Qu, Yujiang Cao… in Journal of Orthopaedic Surgery and Research (2020)

Article

Ultrasonography-guided closed reduction in the treatment of displaced transphyseal fracture of the distal humerus

To evaluate the clinical and radiographic outcomes of ultrasonography-guided closed reduction in the treatment of displaced transphyseal fracture of the distal humerus (TFDH).

Hai Zhou, Ge Zhang, Ming Li, **angyang Qu… in Journal of Orthopaedic Surgery and Research (2020)