8 Result(s)
within
**n Ge Zhang
Medicine & Public Health
Internal Medicine
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Article
Open AccessRecombinant human erythropoietin ameliorates cognitive dysfunction of APP/PS1 mice by attenuating neuron apoptosis via HSP90β
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Article
Open AccessLearning to predict in-hospital mortality risk in the intensive care unit with attention-based temporal convolution network
Dynamic prediction of patient mortality risk in the ICU with time series data is limited due to high dimensionality, uncertainty in sampling intervals, and other issues. A new deep learning method, temporal co...
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Article
Open AccessSTAT3 ameliorates cognitive deficits by positively regulating the expression of NMDARs in a mouse model of FTDP-17
In tauopathies, memory impairment positively strongly correlates with the amount of abnormal tau aggregates; however, how tau accumulation induces synapse impairment is unclear. Recently, we found that human t...
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Article
Open AccessKindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice
In vertebrates, the type 1 parathyroid hormone receptor (PTH1R) is a critical regulator of skeletal development and homeostasis; however, how it is modulated is incompletely understood. Here we report that del...
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Article
Open AccessAntimicrobial susceptibilities of aerobic and facultative gram-negative bacilli isolated from Chinese patients with urinary tract infections between 2010 and 2014
The objective of this study was to investigate the distribution and susceptibility of aerobic and facultative Gram-negative bacilli isolated from Chinese patients with UTIs collected within 48 h (community acq...
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Article
Genetic Architecture of Complex Human Traits: What Have We Learned from Genome-Wide Association Studies?
Genome-wide association studies have identified thousands of genetic variants associated with various complex human traits and diseases. These results opened a window to the genetic architecture of complex hum...
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Article
Open AccessFei-Liu-** ointment inhibits lung cancer growth and invasion by suppressing tumor inflammatory microenvironment
Lung cancer is one of the leading causes of cancer-related mortality worldwide. Conventional chemotherapy and radiotherapy are the primary therapeutic methods for lung cancer with the use of combination therap...
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Article
Regulation of apoptosis proteins in cancer cells by ubiquitin
Ubiquitin inhibitors act at many levels to enhance apoptosis signaling. For TNF-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis signaling, there are at least five mechanisms by which apoptosis are...
