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127 Result(s)
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Article
COVID-19 Vaccine Hesitancy Among People Living with HIV: A Systematic Review and Meta-Analysis
Vaccine hesitancy is one of the top 10 threats to global health, which affects the prevalence and fatality of vaccine-preventable diseases over the world. During the COVID-19 pandemic, people living with HIV (...
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Response Mechanism of Dynamic Tensile Mechanics in Granite Under Microwave Irradiation: Insights from Experiments and Simulations
Microwave-assisted mechanical rock-breaking can effectively solve the problems of low efficiency of hard rock-breaking and severe wear and tear of equipment. This study used granite as the research object and ...
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Open AccessSMAD4 depletion contributes to endocrine resistance by integrating ER and ERBB signaling in HR + HER2− breast cancer
Endocrine resistance poses a significant clinical challenge for patients with hormone receptor-positive and human epithelial growth factor receptor 2-negative (HR + HER2−) breast cancer. Dysregulation of estro...
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Experimental Study on Mechanical Behavior, Fracture Characteristics, and Acoustic Emission Damage Characteristics of Sandstone Under Triaxial Multistage Stress Disturbance
The instability failure of engineering rock mass is caused by the full development of cracks under the combined action of the surrounding rock stress environment and frequent stress disturbance. The developmen...
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Rate-dependent shear behaviors of rock discontinuities with different joint wall strengths
Understanding the shear responses of discontinuities with different joint wall strengths (DDJS) under varying shear rates is crucial for evaluating slope dynamic stability in the Three Gorges Reservoir region,...
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Optimized air-ground data fusion method for mine slope modeling
Refined 3D modeling of mine slopes is pivotal for precise prediction of geological hazards. Aiming at the inadequacy of existing single modeling methods in comprehensively representing the overall and localize...
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Article
Open AccessPrediction of carbapenem-resistant gram-negative bacterial bloodstream infection in intensive care unit based on machine learning
Predicting whether Carbapenem-Resistant Gram-Negative Bacterial (CRGNB) cause bloodstream infection when giving advice may guide the use of antibiotics because it takes 2–5 days conventionally to return the re...
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Open AccessCAV3 alleviates diabetic cardiomyopathy via inhibiting NDUFA10-mediated mitochondrial dysfunction
The progression of diabetic cardiomyopathy (DCM) is noticeably influenced by mitochondrial dysfunction. Variants of caveolin 3 (CAV3) play important roles in cardiovascular diseases. However, the potential rol...
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Introducing N2-fixing tree species into Eucalyptus plantations increases organic phosphorus transformation but decreases its accumulation within aggregates in subtropical China
Soil organic phosphorus (Po) fractions were deemed as potentially significant reservoirs of plant-available phosphorus, profoundly influenced by the physiochemical and biological characteristics of soil. Here ...
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Article
Effects of dark tea soup on rheological, thermal and microstructure characteristics of dough
In order to study the influence of dark tea soup on processing characteristics of dough, texture, thermo-dynamic and rheological properties and microstructure were measured. The dough with tea soup gets better...
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Article
Utilizing metagenomic next-generation sequencing for pathogen detection and diagnosis in lower respiratory tract infections in real-world clinical practice
Infectious etiologies of lower respiratory tract infections (LRTIs) by the conventional microbiology tests (CMTs) can be challenging. Metagenomic next-generation sequencing (mNGS) has great potential in clinic...
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Article
Correction to: Gamma-band-based dynamic functional connectivity in pigeon entopallium during sample presentation in a delayed color matching task
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Article
Gamma-band-based dynamic functional connectivity in pigeon entopallium during sample presentation in a delayed color matching task
Birds have developed visual cognitions, especially in discriminating colors due to their four types of cones in the retina. The entopallium of birds is thought to be involved in the processing of color informa...
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Article
Open AccessPublic discourses and government interventions behind China’s ambitious carbon neutrality goal
Mobilizing the public supports on ambitious climate change goals is crucial for climate action. Here we examine what public discourses have emerged in China around its ambitious carbon neutrality goal and how ...
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Open AccessHIV-related stigma, depression and suicidal ideation among HIV-positive MSM in China: a moderated mediation model
As the HIV epidemic among MSM in China continues, Chinese men who have sex with men (MSM) face various mental health difficulties, including suicide ideation, depression, and stigma. The current study aims to ...
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Open AccessAberrant differentiation of epithelial progenitors is accompanied by a hypoxic microenvironment in the paraquat-injured human lung
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Rapid molecular response to dasatinib in Ph-like acute lymphoblastic leukemia patients with ABL1 rearrangements: case series and literature review
Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a high-risk subtype with a poor prognosis under conventional chemotherapy. Ph-like ALL has a similar gene expression profile to Philad...
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Whole genome sequencing and evolution analyses of Human metapneumovirus
Human metapneumovirus (HMPV) is a major pathogen of acute respiratory tract infections (ARTIs) in children. Whole genome sequence analyses could help understand the evolution and transmission events of this virus...
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Article
Open AccessVAPB-mediated ER-targeting stabilizes IRS-1 signalosomes to regulate insulin/IGF signaling
The scaffold protein IRS-1 is an essential node in insulin/IGF signaling. It has long been recognized that the stability of IRS-1 is dependent on its endomembrane targeting. However, how IRS-1 targets the intr...
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Article
Using neural-genetic hybrid systems for complex decision support
We propose a hybrid system for supporting complex decisions through integrating neural networks (NNs) and genetic algorithms (GAs). We investigate the feasibility of leveraging the synergistic effect of integr...