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  1. No Access

    Article

    Association of the serum levels of saturated fatty acids and mild cognitive impairment: a cross-sectional study

    To investigate the association of serum saturated fatty acids (SFAs) and prevalent mild cognitive impairment (MCI) among middle-aged and elderly Chinese.

    Yuanyuan Li, Qing **ao, LiangKai Chen, Guang Li in European Journal of Clinical Nutrition (2024)

  2. Article

    Open Access

    Overtone photothermal microscopy for high-resolution and high-sensitivity vibrational imaging

    Photothermal microscopy is a highly sensitive pump-probe method for map** nanostructures and molecules through the detection of local thermal gradients. While visible photothermal microscopy and mid-infrared...

    Le Wang, Haonan Lin, Yifan Zhu, **aowei Ge, Mingsheng Li in Nature Communications (2024)

  3. No Access

    Article

    Exploring the relationship between institutional legitimacy and teachers’ innovative behavior: the serial mediating effects of psychological empowerment and normative commitment

    Teachers play a pivotal role in advancing student learning outcomes and nurturing creativity by continuously innovating their practices. Based on the conservation of resources theory and social exchange theory...

    Yun Qu, Ziluo Yan, Kai Chen, Lu Zhou in Current Psychology (2024)

  4. Article

    Open Access

    MiR-223 enhances lipophagy by suppressing CTSB in microglia following lysolecithin-induced demyelination in mice

    Lipid droplet (LD)-laden microglia is a key pathological hallmark of multiple sclerosis. The recent discovery of this novel microglial subtype, lipid-droplet-accumulating microglia (LDAM), is notable for incre...

    Hao Ma, Zhi-lin Ou, Nima Alaeiilkhchi, Yong-quan Cheng in Lipids in Health and Disease (2024)

  5. No Access

    Article

    Nonlinearity optimization for the lattice of SPPC collider ring

    The proposed super proton–proton collider (SPPC) is an energy frontier machine that will possess the capability to explore a significantly broader range of new physics models. The nonlinearity optimization of ...

    Haocheng Xu, Yiwei Wang, Jie Gao, Yukai Chen in Radiation Detection Technology and Methods (2024)

  6. No Access

    Article

    Ti4+ functionalized zirconium metal-organic frameworks with polymer brushes for specific identification of phosphopeptides in human serum and skimmed milk

    In the present study, click chemistry and Schiff base reactions were simultaneously applied to prepare polymer brush (PEG)–functionalized MOF materials (UiO-66-NH2) and immobilized with Ti4+ (MOF-Brush-THBA-Ti4+)...

    Jiakai Chen, Danni Wang, Bing Wang, Chengwei Zhou in Analytical and Bioanalytical Chemistry (2024)

  7. Article

    Open Access

    Spaceflight induces changes in gene expression profiles linked to insulin and estrogen

    Organismal adaptations to spaceflight have been characterized at the molecular level in model organisms, including Drosophila and C. elegans. Here, we extend molecular work to energy metabolism and sex hormone si...

    Begum Aydogan Mathyk, Marshall Tabetah, Rashid Karim in Communications Biology (2024)

  8. No Access

    Article

    Complexin-1 enhances ultrasound neurotransmission in the mammalian auditory pathway

    Unlike megabats, which rely on well-developed vision, microbats use ultrasonic echolocation to navigate and locate prey. To study ultrasound perception, here we compared the auditory cortices of microbats and ...

    Meiling Liu, Changliang Wang, Lifang Huo, Jie Cao, **uguang Mao in Nature Genetics (2024)

  9. Article

    Open Access

    Integration of deep learning and habitat radiomics for predicting the response to immunotherapy in NSCLC patients

    The non-invasive biomarkers for predicting immunotherapy response are urgently needed to prevent both premature cessation of treatment and ineffective extension. This study aimed to construct a non-invasive mo...

    Weimin Caii, **ao Wu, Kun Guo, Yongxian Chen, Yubo Shi in Cancer Immunology, Immunotherapy (2024)

  10. Article

    Open Access

    Risk factors for bloodstream infection among patients admitted to an intensive care unit of a tertiary hospital of Shanghai, China

    Blood flow infections (BSIs) is common occurrences in intensive care units (ICUs) and are associated with poor prognosis. The study aims to identify risk factors and assess mortality among BSI patients admitte...

    Yingchao Cui, Changlin Yi, Chaomin Zhang, Chihui Yang, **nyi Wang in Scientific Reports (2024)

  11. Article

    Open Access

    Diffusion-based deep learning method for augmenting ultrastructural imaging and volume electron microscopy

    Electron microscopy (EM) revolutionized the way to visualize cellular ultrastructure. Volume EM (vEM) has further broadened its three-dimensional nanoscale imaging capacity. However, intrinsic trade-offs betwe...

    Chixiang Lu, Kai Chen, Heng Qiu, **aojun Chen, Gu Chen in Nature Communications (2024)

  12. Article

    Open Access

    Engineering natural microbiomes toward enhanced bioremediation by microbiome modeling

    Engineering natural microbiomes for biotechnological applications remains challenging, as metabolic interactions within microbiomes are largely unknown, and practical principles and tools for microbiome engine...

    Zhepu Ruan, Kai Chen, Weimiao Cao, Lei Meng, Bingang Yang in Nature Communications (2024)

  13. No Access

    Article

    Potassium isotopic evidence for recycling of surface water into the mantle transition zone

    Global water cycling involves interactions between Earth’s interior and its surface environment. Geophysical and mineral physics studies have suggested that the mantle transition zone is hydrous, at least loca...

    Kai-Chen **ng, Feng Wang, Fang-Zhen Teng, Wen-Liang Xu, Yi-Ni Wang in Nature Geoscience (2024)

  14. No Access

    Article

    Semaglutide attenuates pathological electrophysiological remodeling in diabetic cardiomyopathy via restoring Cx43 expression

    Semaglutide is a relatively new anti-hyperglycemic agent that was shown to carry cardioprotective potentials. However, the exact effects of semaglutide on diabetic cardiomyopathy (DCM) and their underlining me...

    Meiling Yan, Kaibin Lin, Dong Huang, **gbo Li, **nkai Qu, Kankai Chen in Endocrine (2024)

  15. No Access

    Article

    Physical insights into non-fullerene organic photovoltaics

    Boosted by the fast development of non-fullerene acceptors, organic photovoltaics (OPVs) have achieved breakthrough power conversion efficiencies — in excess of 20% and approaching those of state-of-the-art cr...

    Jiayu Wang, Yuan **e, Kai Chen, Hongbin Wu, Justin M. Hodgkiss in Nature Reviews Physics (2024)

  16. Article

    Open Access

    A Novel Method to Repair Thin Endometrium and Restore Fertility Based on Menstruation-Derived Stem Cell

    Thin endometrium (TE), which mainly occurs as a result of severe damage to the endometrial basalis, is one of the prominent etiologies of menstrual abnormalities, infertility, and recurrent miscarriage in wome...

    Kai Chen, Huiru Wang, **n Zhao, **gxin Wang, Qi ** in Reproductive Sciences (2024)

  17. No Access

    Article

    Narrow gap welding of 316L thick-section steel with cold metal transition pulsed arc swing

    Narrow gap welding of 316L stainless steel thick plate was carried out using the cold metal transition pulsed wire-arc swing method. The effects of heat input, arc swing, and shielding mode on weld sha** and...

    Wei Meng, Kai Chen, Qinyue Pan, Kai Ye in The International Journal of Advanced Manu… (2024)

  18. No Access

    Article

    The implications of lipid mobility, drug-enhancers (surfactants)-skin interaction, and TRPV1 activation on licorice flavonoid permeability

    Licorice flavonoids (LFs) are derived from perennial herb licorice and have been attaining a considerable interest in cosmetic and skin ailment treatments. However, some LFs compounds exhibited poor permeation...

    Zhuxian Wang, Hongkai Chen, Tao Liang, Yi Hu in Drug Delivery and Translational Research (2024)

  19. Article

    Open Access

    Association between serum vitamin E and bacterial vaginitis in women: a cross-sectional study

    Bacterial vaginitis (BV) is a common vaginal disease. Vitamin E has been shown to reduce BV by enhancing immune function, but no studies have analyzed the relationship between vitamin E and BV at different BMI...

    En-Hui Liu, Wan-Zhe Liao, Hao-Kai Chen, **ao-Ye Huang, Rui-Xuan Li in BMC Women's Health (2024)

  20. No Access

    Article

    Self-adaptive interval dominance-based feature selection for monotonic classification of interval-valued attributes

    Dominance rough set theory is a key mathematical tool for addressing monotonic classification tasks (MCTs). However, current dominance rough set models for feature selection are highly sensitive to noise. Furt...

    Jiankai Chen, Zhongyan Li, Han Su in International Journal of Machine Learning … (2024)

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