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1,918 Result(s)
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Article
Mitigating gut immune adverse effects in CTLA-4 blockade for antitumor efficacy
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Decreasing mitochondrial fission ameliorates HIF-1α-dependent pathological retinal angiogenesis
Angiogenesis plays a critical role in many pathological processes, including irreversible blindness in eye diseases such as retinopathy of prematurity. Endothelial mitochondria are dynamic organelles that unde...
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On the use of VMD-LSTM neural network for approximate earthquake prediction
Earthquake prediction has been widely studied in many fields using various technologies, including machine learning, which is able to explore the underlying information of data. This study adopts machine learn...
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Van der Waals epitaxy of type-II band alignment CsPbI3/TMDC heterostructure for optoelectronic applications
Van der Waals epitaxy allows heterostructure formation without considering the lattice match requirement, thus is a promising method to form 2D/2D and 2D/3D heterojunction. Considering the unique optical prope...
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Open AccessGenetic diversity analysis and core germplasm bank construction in cold resistant germplasm of rubber trees (Hevea brasiliensis)
The rubber tree, Hevea brasiliensis (Willd. ex Adr. de Juss.) Muell. Arg., is the sole plant worldwide utilized for the commercial production of natural rubber. Following years of breeding, there exists a wide ar...
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Analysis of Energy Absorption Characteristics of Corrugated/Windowed Double-Tube Composite Structure Filled with Shear Thickening Fluid
Corrugated tubes with a unique corrugated surface are widely used in various engineering applications due to their ability to reduce impact forces. However, the energy absorption capacity of these tubes is lim...
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Open AccessSuccinate promotes pulmonary fibrosis through GPR91 and predicts death in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is believed to be associated with a notable disruption of cellular energy metabolism. By detecting the changes of energy metabolites in the serum of patients with pulmonary ...
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Application of unmanned aerial vehicle tilt photography technology in geological hazard investigation in China
A major threat is posed to both human society and the environment by geological hazards, necessitating the need for accurate and comprehensive investigation and application in this field. Traditional geologica...
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Personal, external, and psychological factors influencing adherence to nutrition and diet in patients undergoing metabolic/bariatric surgery: a systematic synthesis of mixed methods research
To offer a holistic view of the personal, external, and psychological factors influencing adherence to nutrition and diet in patients undergoing metabolic/bariatric surgery.
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Open AccessThe high expression of ADRM1 in hepatocellular carcinoma is closely related to tumor immune infiltration and is regulated by miR-891a-5p
Liver cancer is one of the most common malignant tumors worldwide. Although some progress has been made in the diagnosis and treatment of Hepatocellular carcinoma (HCC), the diagnosis and treatment of HCC is s...
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Open AccessRapid reconstitution of ubiquitinated nucleosome using a non-denatured histone octamer ubiquitylation approach
Histone ubiquitination modification is emerging as a critical epigenetic mechanism involved in a range of biological processes. In vitro reconstitution of ubiquitinated nucleosomes is pivotal for elucidating t...
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The Effect of Thermosonication Treatment on the Inactivation of Clostridium perfringens Spores
Clostridium perfringens spores, which are extremely resistant and difficult to kill, can easily cause food spoilage and foodborne diseases. In this study, the effect of simultaneous ultrasound and heat (thermoso...
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Open AccessEnantioselective copper-catalyzed azidation/click cascade reaction for access to chiral 1,2,3-triazoles
Chiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challeng...
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Policy measures mitigate the adoption of crop diversification strategies by farmers: insights from the Tibetan Plateau
Crop diversification is a critical adaptation strategy for farmers to cope with climate change, but with the protection of policy measures, farmers might forego pursuing crop diversification. Nevertheless, few...
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Open AccessHematuria after inguinal hernia repair in a child: a case report
Inguinal hernia repair is one of the most common surgical procedures in the pediatric population. While a rare complication, bladder injury can impose a significant burden on patients. This study outlined a ca...
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Open AccessInfluenza virus uses mGluR2 as an endocytic receptor to enter cells
Influenza virus infection is initiated by the attachment of the viral haemagglutinin (HA) protein to sialic acid receptors on the host cell surface. Most virus particles enter cells through clathrin-mediated e...
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Open AccessUnraveling the treatment effects of huanglian jiedu decoction on drug-induced liver injury based on network pharmacology, molecular docking and experimental validation
Huanglian Jiedu Decoction (HJD) is a well-known Traditional Chinese Medicine formula that has been used for liver protection in thousands of years. However, the therapeutic effects and mechanisms of HJD in tre...
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Open AccessRole of lipid metabolism in hepatocellular carcinoma
Hepatocellular carcinoma (HCC), an aggressive malignancy with a dismal prognosis, poses a significant public health challenge. Recent research has highlighted the crucial role of lipid metabolism in HCC develo...
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Optimizing growth and antioxidant function in heat-stressed broilers with vitamin C and betaine supplementation
This study investigates the potential of vitamin C (VC) and/or betaine (Bet) to enhance growth performance, regulate serum metabolism, and bolster antioxidant function aiming to mitigate the impact of heat str...
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Numerical Simulation Study of Co-injection of Pulverized Coal and Hydrogen in the Tuyere-Raceway
Hydrogen can replace partially pulverized coal in the blast furnace injection as the clean and high-calorific energy, which can reduce energy consumption and carbon emission in molten iron production. In this ...