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159 Result(s)
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Article
Open AccessUnveiling the mysteries of HvANS: a study on anthocyanin biosynthesis in qingke (hordeum vulgare L. var. Nudum hook. f.) seeds
Based on our previous research, a full-length cDNA sequence of HvANS gene was isolated from purple and white Qingke. The open reading frame (ORF) in the purple variety Nierumuzha was 1320 base pairs (bp), encodin...
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Article
Open AccessGenetic diversity analysis and DNA fingerprinting of primary Qingke (Hordeum vulgare L. var. nudum Hook. f.) cultivars
To assess the genetic diversity of the primary Qingke cultivars and establish their unique genetic profiles, 837 barley simple sequence repeat (SSR) primers were screened across 12 cultivars. The selection pro...
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Article
Dietary tryptophan effectively decreases the behavioral impacts of handling stresses on the sea cucumber Apostichopus japonicas
Handling stresses have detrimental effects on sea cucumbers, highlighting the importance of finding an effective solution to mitigate these challenges in aquaculture. The present study examined the effects of ...
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Article
The beneficial and pathogenic flora, environmental drivers, and community assembly mechanism of perennial poplar plantation
Soil microorganisms play a crucial role in promoting growth and development, nutrient absorption, and disease resistance in poplar plantations. Long-term planting decays soil nutrient contents and changes the ...
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Article
AMBRA1 promotes intestinal inflammation by antagonizing PP4R1/PP4c mediated IKK dephosphorylation in an autophagy-independent manner
IκB kinase (IKK) complex is central regulators of the NF-κB pathway, and dysregulation of IKK phosphorylation leads to hyperactivation of proinflammatory response in various chronic inflammatory diseases, incl...
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Article
Matching root water uptake patterns to fine root and soil water distributions
Exploring the relationships between water uptake, fine root, and soil water is essential for many fields, such as plant physiology, ecological hydrology, and water conservancy.
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Article
Microbial α-L-arabinofuranosidases: diversity, properties, and biotechnological applications
Arabinoxylans (AXs) are hemicellulosic polysaccharides consisting of a linear backbone of β-1,4-linked xylose residues branched by high content of α-L-arabinofuranosyl (Araf) residues along with other side-chain ...
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Article
Effect of autologous bone marrow stem cells-scaffold transplantation on the ongoing pregnancy rate in intrauterine adhesion women: a randomized, controlled trial
Intrauterine adhesion is a major cause of female reproductive disorders. Although we and others uncontrolled pilot studies showed that treatment with autologous bone marrow stem cells made a few patients with ...
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Chapter
Multimodal Methods for Knowledge Discovery from Bulk and Single-Cell Multi-Omics Data
Multi-omics measurements (bulk and single-cell) are essential to depict the cellular states comprehensively and thus could derive a deep understanding of underlying mechanisms for cellular state changes in man...
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Article
Open AccessTranscriptome analysis reveals core lncRNA-mRNA networks regulating melanization and biomineralization in Patinopecten yessoensis shell-infested by Polydora
Patinopecten yessoensis, a large and old molluscan group, has been one of the most important aquaculture shellfish in Asian countries because of its high economic value. However, the aquaculture of the species ha...
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Article
Open AccessPDK4 rescues high-glucose-induced senescent fibroblasts and promotes diabetic wound healing through enhancing glycolysis and regulating YAP and JNK pathway
During the process of wound healing, fibroblasts migrate to the wound site and perform essential functions in promoting cell proliferation, as well as synthesizing and secreting the extracellular matrix (ECM)....
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Article
Small molecular organic acid potassium promotes rice (Oryza sativa L.) photosynthesis by regulating CBC and TCA cycle
Small molecular organic acids have been found to stimulate plant growth. However, limitition has investigated whether these acids combined with potassium (K) would be more effective in promoting plants growth ...
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Article
Open AccessOncometabolite D-2-hydroxyglutarate—dependent metabolic reprogramming induces skeletal muscle atrophy during cancer cachexia
Cancer cachexia is characterized by weight loss and skeletal muscle wasting. Based on the up-regulation of catabolism and down-regulation of anabolism, here we showed genetic mutation-mediated metabolic reprog...
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Article
Simultaneous profiling of chromatin architecture and transcription in single cells
The three-dimensional structure of chromatin plays a crucial role in development and disease, both of which are associated with transcriptional changes. However, given the heterogeneity in single-cell chromati...
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Article
Natural restoration of degraded karst vegetation shifts soil microbial phosphorus acquisition strategies
Soil phosphorus (P) cycling in karst regions is mainly regulated by microbial activities. Natural restoration has been widely adopted in the degraded karst regions of southwest China. However, the response of ...
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Article
Open AccessHigh temperature influences DNA methylation and transcriptional profiles in sea urchins (Strongylocentrotus intermedius)
DNA methylation plays an important role in life processes by affecting gene expression, but it is still unclear how DNA methylation is controlled and how it regulates gene transcription under high temperature ...
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Article
Open AccessLINC02015 modulates the cell proliferation and apoptosis of aortic vascular smooth muscle cells by transcriptional regulation and protein interaction network
Long intergenic nonprotein coding RNA 2015 (LINC02015) is a long non-coding RNA that has been found elevated in various cell proliferation-related diseases. However, the functions and interactive mechanism of ...
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Article
Opto-juxtacellular interrogation of neural circuits in freely moving mice
Neural circuits are assembled from an enormous variety of neuronal cell types. Although significant advances have been made in classifying neurons on the basis of morphological, molecular and electrophysiologi...
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Article
Granulosa cell mevalonate pathway abnormalities contribute to oocyte meiotic defects and aneuploidy
With aging, abnormalities during oocyte meiosis become more prevalent. However, the mechanisms of aging-related oocyte aneuploidy are not fully understood. Here we performed Hi-C and SMART-seq of oocytes from ...
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Article
Community Characteristics of Soil Ectomycorrhizal Fungi under Different Forests in the Sandy Areas of Northeastern China
Ectomycorrhizal fungal community composition and changes are crucial for evaluating ecological restoration. This study was conducted to reveal significant differences in the community structure and composition...