13 Result(s)

Article

Near-infrared fluorescent amphiphilic polycation wrapped magnetite nanoparticles as multimodality probes

Construction of multifunctional/multimodality nanoparticles for cancer diagnosis and therapy has become an attractive area of investigation. In this report, we designed a multimodality nanoprobe for cell label...

Dan Wang, HongYing Su, YanHong Liu, ChangQiang Wu, ChunChao **a… in Chinese Science Bulletin (2012)

Article

Addendum: Editorial Expression of Concern: DNA-guided genome editing using the Natronobacterium gregoryi Argonaute

Feng Gao, **ao Z Shen, Feng Jiang, Yongqiang Wu, Chunyu Han in Nature Biotechnology (2017)

Article

Retraction Note: DNA-guided genome editing using the Natronobacterium gregoryi Argonaute

Nat. Biotechnol. 34, 768–773 (2016); published online 2 May 2016; addendum published after print 28 November 2016; retracted 26 July 2017; 10.1038/nbt.3547 We are retracting our study because of the continued ...

Feng Gao, **ao Z Shen, Feng Jiang, Yongqiang Wu, Chunyu Han in Nature Biotechnology (2017)

Article

Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement

Random-pattern skin flaps are commonly used and valuable tools in reconstructive surgery, however, post-operative random skin flap necrosis remains a major and common complication. Previous studies have sugges...

Hongqiang Wu, Huanwen Chen, Zhilong Zheng, Jiafeng Li, Jian Ding… in Cell Death & Disease (2019)

Article

FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival

Random-pattern skin flap is commonly used for surgical tissue reconstruction due to its ease and lack of axial vascular limitation. However, ischemic necrosis is a common complication, especially in distal par...

Kailiang Zhou, Huanwen Chen, **ti Lin, Hui Xu, Hongqiang Wu… in Cell Death & Disease (2019)

Article

STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway

Damaged deoxyribonucleic acid (DNA) is a primary pathologic factor for osteoarthritis (OA); however, the mechanism by which DNA damage drives OA is unclear. Previous research demonstrated that the cyclic GMP-A...

Qiang Guo, **miao Chen, Jiaoxiang Chen, Gang Zheng, Chenglong **e… in Cell Death & Disease (2021)

Article

GBP2 facilitates the progression of glioma via regulation of KIF22/EGFR signaling

Identifying the mechanism of glioma progression is critical for diagnosis and treatment. Although studies have shown that guanylate-binding protein 2(GBP2) has critical roles in various cancers, its function i...

Yeqing Ren, Biao Yang, Geng Guo, Jian** Zhang, Yanqi Sun… in Cell Death Discovery (2022)

Article

MFG-E8 alleviates intervertebral disc degeneration by suppressing pyroptosis and extracellular matrix degradation in nucleus pulposus cells via Nrf2/TXNIP/NLRP3 axis

Intervertebral disc degeneration (IVDD) is a chronic age-related degenerative disease accompanied by complex pathophysiological mechanisms. Increasing evidence indicates that NLRP3 inflammasome mediated pyropt...

Haiwei Ma, Chenglong **e, Zhengtai Chen, Gaolu He, Zihan Dai… in Cell Death Discovery (2022)

Article

Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival

The random-pattern skin flap is a crucial technique in reconstructive surgery and flap necrosis caused by ischemia/reperfusion injury is a major postoperative complication. Herein, we investigated the mechanis...

Zhengtai Chen, Hongqiang Wu, Jianxin Yang, Baolong Li, Jian Ding… in Communications Biology (2022)

Article

High-quality chromosome-level de novo assembly of the Trifolium repens

White clover (Trifolium repens L.), an excellent perennial legume forage, is an allotetraploid native to southeastern Europe and southern Asia. It has high nutritional, ecological, genetic breeding, and medicinal...

Hongjie Wang, Yongqiang Wu, Yong He, Guoyu Li, Lichao Ma, Shuo Li… in BMC Genomics (2023)

Article

Stromal cells in the tumor microenvironment: accomplices of tumor progression?

The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cel...

Yan Zhao, Meili Shen, Liangqiang Wu, Haiqin Yang, Yixuan Yao… in Cell Death & Disease (2023)

Article

DTX2 promotes glioma development via regulation of HLTF

Human Deltex 2 (DTX2) is a ubiquitin E3 ligase that functions as an oncogene and has been shown to participate in many human cancers. However, the role of DTX2 in glioma progression has remained obscure. In th...

Ren Li, Yang Chen, Biao Yang, Ziao Li, Peize Li, Yu Chen, Jiayu Li… in Biology Direct (2024)

Article

Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma

Although CD19-specific chimeric antigen receptor (CAR) T cells are curative for patients with relapsed or refractory large B-cell lymphoma (R/R LBCL), disease relapse with tumor antigen-positive remains a chal...

Wen Lei, Ai Zhao, Hui Liu, Chunmei Yang, Cheng Wei, Shanshan Guo… in Cell Discovery (2024)