29 Result(s)

Article

Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) constitutes a rare and aggressive malignancy originating from plasmacytoid dendritic cells (pDCs) with a primarily cutaneous tropism followed by disseminati...

Axel Künstner, Julian Schwarting, Hanno M. Witte, Pengwei **ng… in Leukemia (2024)

Article

Study of the mandibular canal and its surrounding canals by multi-view cone-beam computed tomography

To determine the mandibular anatomical structures by observing cone-beam computed tomography (CBCT) from multiple angles.

Yingqi Chen, Qianting Liao, Yuexia Wu, Rui He, Nanxiang Zhang… in Insights into Imaging (2024)

Article

Association of interleukin-6, ferritin, and lactate dehydrogenase with venous thromboembolism in COVID-19: a systematic review and meta-analysis

Coronavirus disease 2019 (COVID-19) is frequntly accompanied by venous thromboembolism (VTE), and its mechanism may be related to the abnormal inflammation and immune status of COVID-19 patients. It has been p...

Haiyu Liu, Ning**g Guo, Qixian Zheng, Qianyuan Zhang… in BMC Infectious Diseases (2024)

Article

Preconception folic acid supplementation for the prevention of birth defects: a prospective, population-based cohort study in mainland China

Folic acid supplementation is recommended for reducing the risk of birth defects. We aimed to assess the protective association of periconception folic acid supplements with birth defects in real-world setting.

Qiongjie Zhou, Guiying Dong, Qiaomei Wang, Hai** Shen… in BMC Pregnancy and Childbirth (2024)

Article

Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma

Microsatellite instability-high (MSI-H) is a unique genomic status in many cancers. However, its role in the genomic features and immunotherapy in cholangiocarcinoma (CCA) is unclear. This study aimed to syste...

Xu Yang, Baofeng Lian, Nan Zhang, Junyu Long, Yiran Li, **gnan Xue… in BMC Medicine (2024)

Article

Baicalin inhibits IL-1β-induced ferroptosis in human osteoarthritis chondrocytes by activating Nrf-2 signaling pathway

Osteoarthritis (OA) is a common degenerative disease involving articular cartilage, in which ferroptosis of chondrocytes plays an important role. Baicalin (BAI) exerts regulatory effects in a wide range of ort...

Jiuxiang Liu, Hao Zhou, Jiangqi Chen… in Journal of Orthopaedic Surgery and Research (2024)

Article

Exogenous IL-25 ameliorates airway neutrophilia via suppressing macrophage M1 polarization and the expression of IL-12 and IL-23 in asthma

Severe asthma is associated with substantial mortality and has unmet therapeutic need. A subset of severe asthma is characterized by neutrophilic airway inflammation. Classically activated (or M1) macrophages ...

Chenli Chang, Gongqi Chen, Wenliang Wu, Dian Chen, Shengchong Chen… in Respiratory Research (2023)

Article

CACA guidelines for holistic integrative management of esophageal carcinoma

Esophageal carcinoma (EC) is a common malignant tumor of the upper digestive tract worldwide. An analysis of the latest data from cancer centers in China showed that the incidence of EC and the number of death...

Lei Gong, Ming Bai, Liang Dai, Xufeng Guo, Xuefeng Leng… in Holistic Integrative Oncology (2023)

Article

Comprehensive landscape of resistance mechanisms for neoadjuvant therapy in esophageal squamous cell carcinoma by single-cell transcriptomics

Yushang Yang, Yanguo Li, Haopeng Yu… in Signal Transduction and Targeted Therapy (2023)

Article

Attitudes and influencing factors of nursing assistants towards hospice and palliative care nursing in chinese nursing homes: a cross-sectional study

Hospice and palliative care nursing (HPCN) in China is mainly available at public primary care institutions, where nursing homes (NHs) are rarely involved. Nursing assistants (NAs) play an essential role in HP...

Zhuojun Ye, Limei **g, Haoyu Zhang, Yongfa Qin, Hangqi Chen… in BMC Palliative Care (2023)

Article

Construction and analysis of a nomogram prediction model for post-infectious bronchiolitis obliterans in children with adenovirus pneumonia after invasive mechanical ventilation

Post-infectious bronchiolitis obliterans (PIBO) is the most common sequelae in children with adenovirus pneumonia (ADVP). However, there are few studies on the risk factors for PIBO occurrence. This study aims...

Li Peng, Silan Liu, Tian **e, Yu Li, Zhuojie Yang, Yongqi Chen… in BMC Pediatrics (2023)

Article

KIF2A decreases IL-33 production and attenuates allergic asthmatic inflammation

The microtubule-dependent molecular motor protein Kinesin Family Member 2A (KIF2A) is down-regulated in asthmatic human airway epithelium. However, little is known about the roles of KIF2A as well as the possi...

Zhengxia Wang, **g**g Wu, **gxian Jiang… in Allergy, Asthma & Clinical Immunology (2022)

Article

Efficacy and safety of Elian Granules in treating chronic atrophic gastritis: study protocol for a randomized, double-blind, placebo-controlled, multicenter clinical trial

Multifocal atrophic gastritis and intestinal metaplasia are considered to be important links in the gastric precancerous cascade. However, there are no specific drugs for these conditions. Although many studie...

Zhijian Gu, Qingling Jia, Jun Cong, Rong Cen, Yongqi Chen, Chenheng Wu, Biao Gong… in Trials (2022)

Article

CENPO regulated proliferation and apoptosis of colorectal cancer in a p53-dependent manner

Colorectal cancer (CRC) is considered to be a leading cause of cancer-related death. Centromere protein O (CENPO) can prevent the separation of sister chromatids and cell death after spindle injury. Neverthele...

Zhicheng Liu, Chuangqi Chen, Mei Yan, **angtai Zeng, Yuchao Zhang… in Discover Oncology (2022)

Article

A comparison of the clinical effects of thinning and drilling on laser-assisted hatching

To systematically investigate the effects of two methods used for laser-assisted hatching (LAH) on clinical outcomes after day 4 (D4) on frozen-embryo-transfer (FET) cycles. Data from 11471 infertile patients ...

Yujiang Wang, Chuangqi Chen, Jiaying Liang, Lin Fan, Dun Liu… in Lasers in Medical Science (2022)

Article

Epithelial microRNA-30a-3p targets RUNX2/HMGB1 axis to suppress airway eosinophilic inflammation in asthma

Type 2-high asthma is a prominent endotype of asthma which is characterized by airway eosinophilic inflammation. Airway epithelial cells play a critical role in the pathogenesis of asthma. Our previous miRNA p...

Wenliang Wu, Jiali Gao, Dian Chen, Gongqi Chen, Yuchen Feng… in Respiratory Research (2022)

Article

Effect of acupuncture at Zusanli (ST36) point on antral contraction function under ultrasound guidance: study protocol of a randomized controlled trial

Although the relationship between deqi sensations and curative effect has always been controversial, deqi sensations has been regarded as the key indicator of clinical efficacy of acupuncture therapy. There is li...

Yingqi Chen, Yu Bian, Shanshan Li, Yuanyuan Zhao, Jiaying Li, Yuanyi Zheng… in Trials (2021)

Article

IL-36γ-armed oncolytic virus exerts superior efficacy through induction of potent adaptive antitumor immunity

In this study, we aimed to apply the cytokine IL-36γ to cancer immunotherapy by constructing new oncolytic vaccinia viruses (OV) expressing interleukin-36γ (IL-36γ-OVs), leveraging unique synergism between OV and...

Min Yang, Esther Giehl, Chao Feng, Mathilde Feist… in Cancer Immunology, Immunotherapy (2021)

Article

Combined effect of hypertension and hyperuricemia on ischemic stroke in a rural Chinese population

To investigate the combined effect of hypertension and hyperuricemia to the risk of ischemic stroke in a rural Chinese population.

Peng Sun, Mengqi Chen, **aofan Guo, Zhao Li, Ying Zhou, Shasha Yu… in BMC Public Health (2021)

Article

Successful birth after preimplantation genetic testing for a couple with two different reciprocal translocations and review of the literature

Preimplantation genetic testing for chromosomal structural rearrangements (PGT-SR) is widely applied in couples with single reciprocal translocation to increase the chance for a healthy live birth. However, li...

Dun Liu, Chuangqi Chen, **qian Zhang, Mei Dong… in Reproductive Biology and Endocrinology (2021)