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Article
Open AccessIdentification of subgroups and development of prognostic risk models along the glycolysis–cholesterol synthesis axis in lung adenocarcinoma
Lung cancer is one of the most dangerous malignant tumors affecting human health. Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Both glycolytic and cholesterogenic pathways play critica...
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Article
Open AccessARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation
Cancer expression of PD-L1 suppresses anti-tumor immunity. PD-L1 has emerged as a remarkable therapeutic target. However, the regulation of PD-L1 degradation is not understood. Here, we identify several compou...
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Article
Open AccessmTOR Signaling Upregulates CDC6 via Suppressing miR-3178 and Promotes the Loading of DNA Replication Helicase
mTOR signaling pathway is deregulated in most cancers and uncontrolled cell cycle progression is a hallmark of cancer cell. However, the precise molecular mechanisms of the regulation of DNA replication and ch...
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Article
Open AccessPhotoelectrochemical oxidation of organic substrates in organic media
There is a global effort to convert sunlight into fuels by photoelectrochemically splitting water to form hydrogen fuels, but the dioxygen byproduct bears little economic value. This raises the important quest...