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Article
A train bearing imbalanced fault diagnosis method based on extended CCR and multi-scale feature fusion network
The number of fault samples is much less than the normal samples in the actual operation of the train bearing, and the imbalanced characteristics of the fault data significantly decrease the performance of the...
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Article
Open AccessIdentification of subgroups and development of prognostic risk models along the glycolysis–cholesterol synthesis axis in lung adenocarcinoma
Lung cancer is one of the most dangerous malignant tumors affecting human health. Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Both glycolytic and cholesterogenic pathways play critica...
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Article
MOSS: An Open Conversational Large Language Model
Conversational large language models (LLMs) such as ChatGPT and GPT-4 have recently exhibited remarkable capabilities across various domains, capturing widespread attention from the public. To facilitate this ...
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Article
Vision-Aided Damage Detection Method with DIFun Model for Beam-Like Structures: A Novel Information Fusion of DOG Multi-Scale Space of Mode Shape
Structural Health Monitoring (SHM) plays a crucial role in maintaining the integrity and safety of aging infrastructures like bridges and buildings. Since the measurement noise is inevitable, structural damage...
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Article
Open AccessAnalysis of global gene expression using RNA-sequencing reveals novel mechanism of Yanghe **chuan decoction in the treatment of asthma
Yanghe **chuan decoction (YPD) has been used for asthma treatment for many years in China. We sought to understand the mechanism of YPD, and find more potential targets for YPD-based treatment of asthma.
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Article
Bactericidal bissulfone B7 targets bacterial pyruvate kinase to impair bacterial biology and pathogenicity in plants
The prevention and control of rice bacterial leaf blight (BLB) disease has not yet been achieved due to the lack of effective agrochemicals and available targets. Herein, we develop a series of novel bissulfon...
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Article
Open AccessOral microbiota disorder in GC patients revealed by 2b-RAD-M
Microbiota alterations are linked with gastric cancer (GC). However, the relationship between the oral microbiota (especially oral fungi) and GC is not known. In this study, we aimed to apply 2b-RAD sequencing...
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Article
Train bearing fault diagnosis based on multi-sensor data fusion and dual-scale residual network
As one of the vital components of trains, the condition of train bearings is closely related to the safe operation of trains. Traditional bearing fault diagnosis methods based on single sensors are incapable o...
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Article
Coordinately unsaturated nickel single atom electrocatalyst for efficient CO2 conversion
Single-atom catalysts (SACs) have shown unexpected catalytic activity due to their unique electronic structure and coordination environment. Nonetheless, the synthesis of an atomically precise low-coordination...
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Article
Recent advances in regulating the local environment of M-N4 structure for tailored chemical reactions
Single-atom catalysts (SACs) with M-N4 structure have drawn significant attention due to the facile preparation, maximum atom efficiency, unique electronic properties, uniform active sites, and excellent activity...
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Article
Open AccessGenetic associations between circulating metabolic biomarkers and lung cancer in East Asians and Europeans
Metabolic biomarkers are reported to be associated with the risk of lung cancer (LC). However, the observed associations from epidemiological studies are either inconsistent or inconclusive.
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Article
Open AccessThe role of LINC01419 in regulating the cell stemness in lung adenocarcinoma through recruiting EZH2 and regulating FBP1 expression
Recent years have witnessed a growing academic interest in the effects of lncRNAs on tumors. LINC01419 is found to facilitate proliferation and metastasis of lung adenocarcinoma (LUAD) cells, but there is a gr...
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Article
Electrolyzer and Catalysts Design from Carbon Dioxide to Carbon Monoxide Electrochemical Reduction
Electrochemical CO2 reduction reaction (CO2RR) has attracted considerable attention in the recent decade for its critical role in the storage of renewable energy and fulfilling of the carbon cycle, and catalysts ...
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Article
High mass-specific reactivity of a defect-enriched Ru electrocatalyst for hydrogen evolution in harsh alkaline and acidic media
A reasonable design strategy to improve the utilization of noble metal electrocatalysts for the hydrogen evolution reaction (HER) is crucial to simplify the process flow and accelerate the future renewable ene...
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Article
Open AccessARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation
Cancer expression of PD-L1 suppresses anti-tumor immunity. PD-L1 has emerged as a remarkable therapeutic target. However, the regulation of PD-L1 degradation is not understood. Here, we identify several compou...
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Chapter and Conference Paper
Improvement of RPL Routing Strategy Based on 6LoWPAN
The routing protocol for low-power and lossy networks (RPL) has become the standard routing protocol for the Internet of things (IoT). This paper studies the application of RPL in the 6LoWPAN. In the topology ...
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Article
Cullin 3 overexpression inhibits lung cancer metastasis and is associated with survival of lung adenocarcinoma
Cullin 3 (CUL3), a molecular scaffold of Cullin-RING ubiquitin ligase, plays an important role in regulating biological processes through modulating the ubiquitylation and degradation of various protein substr...
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Article
Open AccessCircRNA-ENO1 promoted glycolysis and tumor progression in lung adenocarcinoma through upregulating its host gene ENO1
Lung adenocarcinoma (LUAD) has long been one of the predominant reasons for the global cancer-linked mortality. The tumor progression is shown by several studies to be promoted by increased glycolysis. Enolase...
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Article
A new local density and relative distance based spectrum clustering
A novel local density and relative distance-based spectrum clustering (LDRDSC) algorithm is proposed for multidimensional data clustering. The density spectra consider both redefined local densities and relati...
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Article
Open AccessmTOR Signaling Upregulates CDC6 via Suppressing miR-3178 and Promotes the Loading of DNA Replication Helicase
mTOR signaling pathway is deregulated in most cancers and uncontrolled cell cycle progression is a hallmark of cancer cell. However, the precise molecular mechanisms of the regulation of DNA replication and ch...
