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  1. No Access

    Article

    Evaluation of fragility fracture risk using deep learning based on ultrasound radio frequency signal

    It was essential to identify individuals at high risk of fragility fracture and prevented them due to the significant morbidity, mortality, and economic burden associated with fragility fracture. The quantitat...

    Wenqiang Luo, Jionglin Wu, Zhiwei Chen, Peidong Guo, Qi Zhang, Baiying Lei in Endocrine (2024)

  2. Article

    Open Access

    Threshold of hyperglycaemia associated with mortality in critically ill patients: a multicentre, prospective, observational study using continuous glucose monitoring

    Continuous glucose monitoring (CGM) provides comprehensive information on the exposure to dysglycaemia. This study aimed to investigate the threshold of hyperglycaemia related to mortality risk in critically i...

    Yaxin Wang, Siwan Li, **gyi Lu, Kaixuan Feng, **aoli Huang, Fangbao Hu in Diabetologia (2024)

  3. Article

    Open Access

    Structural deviations of the posterior fossa and the cerebellum and their cognitive links in a neurodevelopmental deletion syndrome

    High-impact genetic variants associated with neurodevelopmental disorders provide biologically-defined entry points for mechanistic investigation. The 3q29 deletion (3q29Del) is one such variant, conferring a ...

    Esra Sefik, Kuaikuai Duan, Yiheng Li, Brittney Sholar in Molecular Psychiatry (2024)

  4. No Access

    Article

    Evaluation of tumor microvasculature with 3D ultrasound localization microscopy based on 2D matrix array

    Evaluation of tumor microvascular morphology is of great significance in tumor diagnosis, therapeutic effect prediction, and surgical planning. Recently, two-dimensional ultrasound localization microscopy (2DU...

    Changlu Zhang, Shuang Lei, Aiqing Ma, Bing Wang, Shuo Wang in European Radiology (2024)

  5. Article

    Open Access

    Correction: NOD2 attenuates osteoarthritis via reprogramming the activation of synovial macrophages

    Changchuan Li, Zhuji Ouyang, Yuhsi Huang, Sipeng Lin in Arthritis Research & Therapy (2024)

  6. Article

    Open Access

    NOD2 attenuates osteoarthritis via reprogramming the activation of synovial macrophages

    Synovial inflammation, which precedes other pathological changes in osteoarthritis (OA), is primarily initiated by activation and M1 polarization of macrophages. While macrophages play a pivotal role in the in...

    Changchuan Li, Zhuji Ouyang, Yuhsi Huang, Sipeng Lin in Arthritis Research & Therapy (2023)

  7. Article

    Open Access

    The combination of lactate level, lactate clearance and APACHE II score better predicts short-term outcomes in critically Ill patients: a retrospective cohort study

    The mortality rate is high in critically ill patients due to the difficulty of diagnosis and treatment. Thus, it is very important to explore the predictive value of different indicators related to prognosis i...

    Yongmei Cao, Sijia Yao, Jiawei Shang, Feng **, Qin Tan, Zijun Tian in BMC Anesthesiology (2022)

  8. Article

    Accuracy of the intermittently scanned continuous glucose monitoring system in critically ill patients: a prospective, multicenter, observational study

    Continuous glucose monitoring (CGM) has the potential to improve glucose control in the intensive care unit (ICU) setting. We sought to evaluate the accuracy of the intermittently scanned CGM (isCGM) system in...

    Weifeng Huang, Siwan Li, **gyi Lu, Yun Shen, Yaxin Wang, Yufei Wang in Endocrine (2022)

  9. Article

    Open Access

    Comparative efficacy of 5 suture configurations for arthroscopic rotator cuff tear repair: a network meta-analysis

    Rotator cuff tear is one of the most common complaint with shoulder pain, disability, or dysfunction. So far, different arthroscopic techniques including single row (SR), double row (DR), modified Mason–Allen ...

    Wei Wang, Hui Kang, Hongchuan Li, Jian Li in Journal of Orthopaedic Surgery and Research (2021)

  10. No Access

    Article

    Dual Locking Plate Osteosynthesis for 3- or 4-Part Proximal Humeral Fractures Combined with Multiple Fractures of the Greater Tuberosity

    This retrospective study was conducted to evaluate the efficacy of dual locking plate osteosynthesis for treating 3- or 4-part proximal humeral fractures combined with multiple fractures of the greater tuberos...

    Yongchuan Li, Nan Lu, Fan Zhang, Zhibin Zhou in Indian Journal of Orthopaedics (2021)

  11. Article

    Open Access

    Locking plate combined with titanium cable for Neer type II distal clavicle fractures

    There is controversy about the optimal strategy treatment of unstable distal clavicle fractures. We explored use of a surgical strategy: combination of a distal clavicle locking plate and a titanium cable. The...

    Fan Zhang, Qiang Fu, Yongchuan Li, Nan Lu, Aimin Chen in BMC Musculoskeletal Disorders (2021)

  12. No Access

    Article

    Intratumor δ-catenin heterogeneity driven by genomic rearrangement dictates growth factor dependent prostate cancer progression

    Only a small number of genes are bona fide oncogenes and tumor suppressors such as Ras, Myc, β-catenin, p53, and APC. However, targeting these cancer drivers frequently fail to demonstrate sustained cancer remiss...

    Mingchuan Li, Jongdee Nopparat, Byron J. Aguilar, Yan-hua Chen, Jiao Zhang in Oncogene (2020)

  13. Article

    Open Access

    Long-term oncologic outcomes of radiotherapy combined with maximal androgen blockade for localized, high-risk prostate cancer

    To assess the oncologic outcomes of radiation therapy (RT) combined with maximal androgen blockade (MAB) and prostate-specific antigen (PSA) kinetics in patients with localized, high-risk prostate carcinoma (P...

    Yong Luo, Mingchuan Li, Hengzhi Qi, Jiahui Zhao in World Journal of Surgical Oncology (2018)

  14. Article

    Open Access

    Study protocol for The Emory 3q29 Project: evaluation of neurodevelopmental, psychiatric, and medical symptoms in 3q29 deletion syndrome

    3q29 deletion syndrome is caused by a recurrent hemizygous 1.6 Mb deletion on the long arm of chromosome 3. The syndrome is rare (1 in 30,000 individuals) and is associated with mild to moderate intellectual d...

    Melissa M. Murphy, T. Lindsey Burrell, Joseph F. Cubells in BMC Psychiatry (2018)

  15. No Access

    Article

    All-arthroscopic anatomical reconstruction of anterior talofibular ligament using semitendinosus autografts

    We introduced a new technique of all-arthroscopic anatomical anterior talofibular ligament (ATFL) reconstruction using semitendinosus autografts.

    Bin Song, Changchuan Li, Na Chen, Zhong Chen, Yan Zhang in International Orthopaedics (2017)

  16. Article

    Open Access

    Pure retroperitoneal natural orifice translumenal endoscopic surgery (NOTES) transvaginal nephrectomy using standard laparoscopic instruments: a safety and feasibility study in a porcine model

    Among the different organs used for NOTES (natural orifice translumenal endoscopic surgery) technique, the transvaginal approach may be the optimal choice because of a simple and secure closure of colpotomy si...

    Dechao Wei, Yili Han, Mingchuan Li, Yongxing Wang, Yatong Chen, Yong Luo in BMC Urology (2016)

  17. Article

    Open Access

    Comparison of transverse and modified subtrochanteric femoral shortening osteotomy in total hip arthroplasty for developmental dysplasia of hip: a meta-analysis

    Subtrochanteric femoral shortening osteotomy is a crucial procedure to prevent nerve injury in total hip arthroplasty for severe developmental dysplasia of the hip. Transverse osteotomy was first applied, and ...

    Changchuan Li, Chi Zhang, Maolin Zhang, Yue Ding in BMC Musculoskeletal Disorders (2014)

  18. No Access

    Article

    Treatment of distal tibial shaft fractures by three different surgical methods: a randomized, prospective study

    A few studies focused on the methods of treatment for displaced distal tibial shaft fractures have been published, all of which compared two different methods. In this randomized, prospective study, we aimed t...

    Yongchuan Li, ** Jiang, Qinghe Guo, Lei Zhu, Tianwen Ye in International Orthopaedics (2014)

  19. No Access

    Article

    Locally activity-released bifunctional fusion protein enhances antithrombosis and alleviates bleeding risk

    Despite the fact that lytic therapy of thromboembolic disorder has been achieved, reocclusion of the damaged vessels and bleeding complication frequently reduce the therapeutic effect. In order to prevent the ...

    Bingxing Shi, Ai** Yu, Yuying Liu, **gchuan Li in Journal of Thrombosis and Thrombolysis (2007)