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Article
Open AccessSingle-cell transcriptome atlas of testes from mice with high-fat diets
Obesity is accompanied by multiple known health risks and increased morbidity, and obese men display reduced reproductive health. However, the impact of obesity on the testes at the molecular levels remain ina...
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Article
Open AccessEffective delivery of miR-150-5p with nucleus pulposus cell-specific nanoparticles attenuates intervertebral disc degeneration
The use of gene therapy to deliver microRNAs (miRNAs) has gradually translated to preclinical application for the treatment of intervertebral disc degeneration (IDD). However, the effects of miRNAs are hindere...
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Article
Interaction mechanisms of ACE inhibitory peptides: molecular docking and molecular dynamics simulation studies on five wheat gluten derived peptides
The angiotensin I-converting enzyme (ACE) inhibitory activity of five wheat gluten-derived peptides Ala-Pro-Ser-Tyr (APSY), Leu-Val-Ser (LVS), Leu-Tyr (LY), Arg-Gly-Gly-Tyr (RGGY), and Tyr-Gln (YQ) was investi...
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Article
Open AccessResponse of laterally loaded finned piles in sand
This paper investigates the response of finned piles in sand subjected to static lateral load through laboratory tests and full-scale field tests. Firstly, model tests were carried out on free headed single pi...
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Article
Open AccessAn analysis of differences in Carbapenem-resistant Enterobacterales in different regions: a multicenter cross-sectional study
This study aimed to explore the characteristics of carbapenem-resistant Enterobacterales (CRE) patients in the intensive care unit (ICU) in different regions of Henan Province to provide evidence for the targeted...
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Article
Open AccessOdontoid incidence: a constant cervical anatomical feature evident in standing plain radiographs and supine magnetic resonance images
To assess whether there is a difference between measurements of odontoid incidence (OI) and other cervical sagittal parameters by X-ray radiography and those by supine magnetic resonance imaging (MRI).
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Chapter and Conference Paper
Research on Structure Optimization of Axial Magnetic Bearing for Magnetic Levitation System
Axial magnet bearing has the advantages of adjustable stiffness and strong adaptability. However, when it is integrated into the magnetic levitation system of high-speed, the length of axial and radial often l...
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Chapter and Conference Paper
Research on the Reasons for Abnormal Changes in the Operation Status of Domino’s Pizza
The spread of COVID-19 in 2020 had a huge negative impact on the catering industry, with the stocks of almost all catering companies falling. However, Domino’s Pizza shares rose sharply in the early days of th...
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Article
Open AccessTherapeutic effects of isoquercetin on ovariectomy-induced osteoporosis in mice
Bone marrow mesenchymal stem cells (BMSCs) are non-hematopoietic multipotent stem cells capable of differentiating into mature cells. Isoquercetin, an extract from natural sources, has shown promise as a poten...
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Article
Upgrading the accumulation of ginsenoside Rd in Panax notoginseng by a novel glycosidase-producing endophytic fungus G11-7
A novel endophytic fungus producing beta-glucosidase was isolated and characterized from pigeon pea (Cajanus cajan [L.] Millsp.), which has excellent properties in converting ginsenoside Rb1 to ginsenoside Rd in
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Article
Publisher Correction: Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction
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Article
Downregulation of glycoprotein non-metastatic melanoma protein B prevents high glucose-induced angiogenesis in diabetic retinopathy
Diabetic retinopathy (DR), a microvascular complication characterized by abnormal angiogenesis, is the most common reason for irreversible blindness. Glycoprotein non-metastatic melanoma protein B (GPNMB), as ...
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Article
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction
Membrane dynamics are important to the integrity and function of mitochondria. Defective mitochondrial fusion underlies the pathogenesis of multiple diseases. The ability to target fusion highlights the potent...
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Article
Smart ionic liquid/water mixture system with dual stimuli-response to temperature and CO2
Stimuli-responsive materials have important applications in chemistry and chemical engineering. Here, we synthesized five different polyetheramine-fatty acids (PEFA) ionic liquids (ILs), possessing the dual st...
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Article
Open AccesscircFLNA promotes intestinal injury during abdominal sepsis through Fas-mediated apoptosis pathway by sponging miR-766-3p
Intra-abdominal infections are the second most common cause of sepsis in the intensive care unit. Intestinal epithelial injury due to abdominal sepsis results in a variety of pathological changes, such as inte...
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Chapter and Conference Paper
A Simple and Effective Identification Method for Transient Pulse Wave Propagation Resulted from Overhead Transmission Line Fault
This paper presents a simple and effective method for extracting the identification quantity of transient pulse waveform produced by the overhead transmission line fault. This method employs the second-order t...
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Chapter and Conference Paper
Approximate Simulation of Low Frequency Magnetic Shielding of a Rectangular Shielding Box Composed of Perforated Walls
The low frequency magnetic shielding of a rectangular metallic box, with all walls perforated periodical holes, is studied. The finite conductivity box with holes and the perfect conductivity box with holes ar...
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Chapter and Conference Paper
A Finite-Time Posture Control Strategy for the Swarm Underactuated Robots
Under the background of industrial machinery automation. The swarm robots are required to cooperate to complete complex and accurate works in finite-time and create more relative residual value. Based on the i...
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Article
Tumor-derived exosomes drive pre-metastatic niche formation in lung via modulating CCL1+ fibroblast and CCR8+ Treg cell interactions
Since the lung is one of the most common sites for cancer metastasis, it could provide a suitable microenvironment for pre-metastatic niche (PMN) formation to facilitate tumor cell colonization. Regulatory T c...
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Article
Concentrations, distribution, and risk assessment of endosulfan residues in the cotton fields of northern **njiang, China
In the current study, surface soil samples were collected from cotton fields in Shawan and Shihezi areas in northern **njiang and tested for endosulfan residues using gas chromatography-mass spectrometry. Resu...
