11 Result(s)

Article

HMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis

Chemotherapy is a primary treatment for esophageal squamous cell carcinoma (ESCC). Resistance to chemotherapeutic drugs is an important hurdle to effective treatment. Understanding the mechanisms underlying ch...

**g-Yu Yang, **n-Yuan Lei, Kai-Yue He, **-Rong Guo, Meng-Jie Liu… in Cell Death & Disease (2024)

Article

Correction: Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development

Wan-jun Yang, Rong-chang Cao, Wang **ao, **ao-lou Zhang, Hao Xu… in Cell Death & Disease (2022)

Article

Retraction Note: Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway

Hong-li Jiao, Bin-shu Weng, Shan-shan Yan, Zi-mo Lin, Shu-yang Wang… in Cell Death & Disease (2022)

Article

Elevated nuclear localization of glycolytic enzyme TPI1 promotes lung adenocarcinoma and enhances chemoresistance

Increased glycolysis is a hallmark of tumor, which can provide tumor cells with energy and building blocks to promote cell proliferation. Recent studies have shown that not only the expression of glycolytic ge...

Peng Liu, Si-Jia Sun, Ying-Jie Ai, Xu Feng, Yi-Min Zheng, Yun Gao… in Cell Death & Disease (2022)

Article

Cancer-associated fibroblast-derived CXCL11 modulates hepatocellular carcinoma cell migration and tumor metastasis through the circUBAP2/miR-4756/IFIT1/3 axis

Cancer-associated fibroblasts (CAFs) are commonly acquired activated extracellular matrix (ECM)-producing myofibroblasts, a phenotypes with multiple roles in hepatic fibrogenesis and carcinogenesis via crossta...

Gao Liu, Jian Sun, Zhang-Fu Yang, Cheng Zhou, Pei-Yun Zhou… in Cell Death & Disease (2021)

Article

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing

ZD55-IL-24 is similar but superior to the oncolytic adenovirus ONYX-015, yet the exact mechanism underlying the observed therapeutic effect is still not well understood. Here we sought to elucidate the underly...

Hai-Jun Hu, **u Liang, Hai-Lang Li, Chun-Ming Du, Jia-Li Hao… in Cell Death & Disease (2020)

Article

RETRACTED ARTICLE: Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway

Oxysterol-binding protein like protein 3 (OSBPL3) has been shown involving in the development of several human cancers. However, the relationship between OSBPL3 and colorectal cancer (CRC), particularly the ro...

Hong-li Jiao, Bin-shu Weng, Shan-shan Yan, Zi-mo Lin, Shu-yang Wang… in Cell Death & Disease (2020)

Article

Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer

Regulatory T cells (Tregs) represent an important contributor to cancer immune escape, but the molecular mechanism responsible for Treg expansion in tumors is heterogeneous and unclear. Here, we investigated t...

Yi-Na Liu, Han Zhang, Lin Zhang, Ting-Ting Cai, Dai-Jia Huang… in Cell Death & Disease (2019)

Article

BAP1 acts as a tumor suppressor in intrahepatic cholangiocarcinoma by modulating the ERK1/2 and JNK/c-Jun pathways

Current therapeutic options for intrahepatic cholangiocarcinoma (ICC) are very limited, which is largely attributed to poor understanding of molecular pathogenesis of ICC. Breast cancer type 1 susceptibility p...

Xu-**ao Chen, Yue Yin, Jian-Wen Cheng, Ao Huang, Bo Hu, **n Zhang… in Cell Death & Disease (2018)

Article

Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration

Treatment of intervertebral disc degeneration (IDD) seeks to prevent senescence and death of nucleus pulposus (NP) cells. Previous studies have shown that sirt6 exerts potent anti-senescent and anti-apoptotic ...

Jian Chen, Jun-Jun **e, Meng-Yun **, Yun-Tao Gu, Cong-Cong Wu… in Cell Death & Disease (2018)

Article

Upregulation of B7-H4 promotes tumor progression of intrahepatic cholangiocarcinoma

Recent reports show that B7-H4 is highly expressed in a variety of tumor cells, functions as a negative regulator of T cells and then promotes tumor progression. However, its expression and role in intrahepati...

Nan **e, Jia-Bin Cai, Lu Zhang, Peng-Fei Zhang, Ying-Hao Shen… in Cell Death & Disease (2017)