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The role of CYP2C19 in amitriptyline N-demethylation in Chinese subjects

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  1. Article

    Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine

    Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).Methods: The data of patie...

    Zou **-pan, Hua Bao-**, Chen Chang-huai in Chinese Journal of Integrative Medicine (2003)

  2. Article

    The role of water channel proteins and nitric oxide signaling in rice seed germination

    Previous studies have demonstrated the possible role of several aquaporins in seed germination. But systematic investigation of the role of aquaporin family members in this process is lacking. Here, the develo...

    Hong-Yan Liu, **n Yu, Da-Yong Cui, Mei-Hao Sun, Wei-Ning Sun in Cell Research (2007)

  3. Article

    Nitroglycerin enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via nitric oxide pathway

    To investigate the effect of nitroglycerin (NTG) on cell proliferation and osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells (HBMSC) and its mechanisms.

    Li Huang, Ni Qiu, Che Zhang, Hong-yan Wei, Ya-lin Li in Acta Pharmacologica Sinica (2008)

  4. Article

    Open Access

    A reporter gene system for screening inhibitors of Wnt signaling pathway

    Abnormal activation of canonical Wnt signaling has been associated with various types of cancer. Inhibitory reagents targeting the Wnt signaling have great potential to inhibit the growth of relevant tumors. H...

    **ng-Yao Li, Yuan-Yuan Wang, Chun-Mao Yuan in Natural Products and Bioprospecting (2013)

  5. Article

    Open Access

    Diversity of endophytic fungi from roots of Panax ginseng and their saponin yield capacities

    Endophytes of medicinal plants have the capacity to synthesis same or similar active substances with their hosts. To investigate the diversity and capacity to produce saponins of endophytic fungi of Panax ginseng

    Hao Wu, Hong-Yan Yang, **ang-Lin You, Yu-Hua Li in SpringerPlus (2013)

  6. Article

    Open Access

    Glycemic control among patients in China with type 2 diabetes mellitus receiving oral drugs or injectables

    The prevalence of type 2 diabetes mellitus (T2DM) is increasing rapidly among Chinese adults, and limited data are available on T2DM management and the status of glycemic control in China. We assessed the effi...

    Li-Nong Ji, Ju-Ming Lu, **ao-Hui Guo, Wen-Ying Yang, Jian-** Weng in BMC Public Health (2013)

  7. Article

    Development of Anxiety-Like Behavior via Hippocampal IGF-2 Signaling in the Offspring of Parental Morphine Exposure: Effect of Enriched Environment

    Opioid addiction is a major social, economic, and medical problem worldwide. Long-term adverse consequences of chronic opiate exposure not only involve the individuals themselves but also their offspring. Adol...

    Chang-Qi Li, Yan-Wei Luo, Fang-Fang Bi, Tao-Tao Cui, Ling Song in Neuropsychopharmacology (2014)

  8. Article

    Open Access

    Number of negative lymph nodes can predict survival of breast cancer patients with four or more positive lymph nodes after postmastectomy radiotherapy

    This study was conducted to assess the prognostic value of the number of negative lymph nodes (NLNs) in breast cancer patients with four or more positive lymph nodes after postmastectomy radiotherapy (PMRT).

    San-Gang Wu, Jia-Yuan Sun, Juan Zhou, Feng-Yan Li, Hao Zhou, Qin Lin in Radiation Oncology (2014)

  9. Article

    Open Access

    Folate intake, serum folate levels, and prostate cancer risk: a meta-analysis of prospective studies

    Studies have reported inconsistent results concerning the existence of associations of folate intake and serum folate levels with prostate cancer risk. This study sought to summarise the evidence regarding the...

    Rong Wang, Yan Zheng, **g-Yang Huang, Ai-Qin Zhang, Yu-Hao Zhou in BMC Public Health (2014)

  10. Article

    Open Access

    Transcriptome analysis of Panax vietnamensis var. fuscidicus discovers putative ocotillol-type ginsenosides biosynthesis genes and genetic markers

    P. vietnamensis var. fuscidiscus, called “Yesanqi” in Chinese, is a new variety of P. vietnamensis, which was first found in **** County, the southern part of Yunnan Province, China. Compare...

    Guang-Hui Zhang, Chun-Hua Ma, Jia-** Zhang, Jun-Wen Chen, Qing-Yan Tang in BMC Genomics (2015)

  11. Article

    Open Access

    The endophytic fungi of Salvia miltiorrhiza Bge.f. alba are a potential source of natural antioxidants

    Salvia miltiorrhiza Bge. f. alba is a traditional Chinese herbal drug with special pharmacological effect on thromboangiitis obliterans. However, the nature source of S.miltiorrhiza Bge.f.alba is now in short sup...

    Yan-Ling Li, **ao-Ming **n, Zheng-Yao Chang, Ren-Jiu Shi in Botanical Studies (2015)

  12. Article

    Erratum to: Fungal diversity notes 111–252—taxonomic and phylogenetic contributions to fungal taxa

    Hiran A. Ariyawansa, Kevin D. Hyde, Subashini C. Jayasiri, Bart Buyck in Fungal Diversity (2015)

  13. Article

    Open Access

    The impact of the cumulative dose of cisplatin during concurrent chemoradiotherapy on the clinical outcomes of patients with advanced-stage nasopharyngeal carcinoma in an era of intensity-modulated radiotherapy

    The impact of cumulative dose of cisplatin on clinical outcomes of nasopharyngeal carcinoma (NPC) patients who received intensity-modulated radiotherapy (IMRT) was evaluated.

    Shan-Shan Guo, Lin-Quan Tang, Lu Zhang, Qiu-Yan Chen, Li-Ting Liu, Ling Guo in BMC Cancer (2015)

  14. Article

    Open Access

    Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population

    Congenital heart defects (CHDs) are one of the most common human birth defects worldwide. TBX20 is a crucial transcription factor for the development of embryonic cardiovascular system. Previous studies have d...

    Li-Wei Yu, Feng Wang, Xue-Yan Yang, Shu-Na Sun, Yu-Fang Zheng in Scientific Reports (2016)

  15. Article

    Dexamethasone suppresses the growth of human non-small cell lung cancer via inducing estrogen sulfotransferase and inactivating estrogen

    Dexamethasone (DEX) is a widely used synthetic glucocorticoid, which has shown anti-cancer efficacy and anti-estrogenic activity. In this study we explored the possibility that DEX might be used as an endocrin...

    Li-jie Wang, Jian Li, Fang-ran Hao, Yin Yuan, **g-yun Li in Acta Pharmacologica Sinica (2016)

  16. Article

    Open Access

    Surgery Combined with Radiotherapy Improved Survival in Metastatic Esophageal Cancer in a Surveillance Epidemiology and End Results Population-based Study

    This retrospective study used a population-based national registry to determine the impact of local treatment modalities on survival in patients with metastatic esophageal cancer (EC). The Surveillance Epidemi...

    San-Gang Wu, Wei-Hao **e, Zhao-Qiang Zhang, Jia-Yuan Sun, Feng-Yan Li in Scientific Reports (2016)

  17. Article

    Open Access

    Effect of caesarean section on maternal and foetal outcomes in acute fatty liver of pregnancy: a systematic review and meta-analysis

    Several studies have reported a positive association between caesarean section for expeditious pregnancy termination and perinatal outcomes in acute fatty liver of pregnancy (AFLP); however, the risks remain u...

    Hong-Yan Wang, Qing Jiang, Hao Shi, Yun-Qing Xu, Ai-Chao Shi in Scientific Reports (2016)

  18. Article

    Open Access

    Functional characterization of GmBZL2 (AtBZR1 like gene) reveals the conserved BR signaling regulation in Glycine max

    Brassinosteroids (BRs) play key roles in plant growth and development, and regulate various agricultural traits. Enhanced BR signaling leads to increased seed number and yield in Arabidopsis bzr1-1D (AtBZR1P234L,...

    Yu Zhang, Yan-Jie Zhang, Bao-Jun Yang, **an-**an Yu, Dun Wang in Scientific Reports (2016)

  19. Article

    Open Access

    Economic burden and its associated factors of hospitalized patients infected with A (H7N9) virus: a retrospective study in Eastern China, 2013–2014

    H7N9 continues to cause human infections and remains a pandemic concern. Understanding the economic impacts of this novel disease is important for making decisions on health resource allocation, including infe...

    **ang Huo, Li-Ling Chen, Lei Hong, Lun-Hui **ang in Infectious Diseases of Poverty (2016)

  20. Article

    Open Access

    Prediction of phosphothreonine sites in human proteins by fusing different features

    Phosphorylation is one of the most important protein post-translation modifications. With the rapid development of high-throughput mass spectrometry, phosphorylation site data is rapidly accumulating, which pr...

    Ya-Wei Zhao, Hong-Yan Lai, Hua Tang, Wei Chen, Hao Lin in Scientific Reports (2016)

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