38 Result(s)
within
**g-Yan Hao
English
Science, Humanities and Social Sciences, multidisciplinary
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Article
Identification of a novel GNAS mutation for pseudohypoparathyroidism in a Chinese family
Pseudohypoparathyroidism (PHP) is a heterogeneous group of diseases characterized by hormone resistance to receptors that stimulate adenylate cyclase. PHP-Ia patients show specific Gs-alpha protein deficiency,...
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The influence of the genetic and non-genetic factors on bone mineral density and osteoporotic fractures in Chinese women
To investigate the effects of genetic and non-genetic factors on bone mineral densities (BMDs) and osteoporotic fractures. This was a cross-sectional study to investigate the relationships between 18 SNPs and ...
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Article
Open AccessDiversity of endophytic fungi from roots of Panax ginseng and their saponin yield capacities
Endophytes of medicinal plants have the capacity to synthesis same or similar active substances with their hosts. To investigate the diversity and capacity to produce saponins of endophytic fungi of Panax ginseng
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Article
The bone-preserving effects of exendin-4 in ovariectomized rats
Exendin-4 was found to be beneficial to the skeleton in diabetic rodents. In this study, we assessed the changes of bone mineral densities (BMDs) and quality in non-diabetic ovariectomized (OVX) rats after tre...
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Article
Open AccessMild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population
Congenital heart defects (CHDs) are one of the most common human birth defects worldwide. TBX20 is a crucial transcription factor for the development of embryonic cardiovascular system. Previous studies have d...
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Article
Open AccessSurgery Combined with Radiotherapy Improved Survival in Metastatic Esophageal Cancer in a Surveillance Epidemiology and End Results Population-based Study
This retrospective study used a population-based national registry to determine the impact of local treatment modalities on survival in patients with metastatic esophageal cancer (EC). The Surveillance Epidemi...
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Article
Open AccessEffect of caesarean section on maternal and foetal outcomes in acute fatty liver of pregnancy: a systematic review and meta-analysis
Several studies have reported a positive association between caesarean section for expeditious pregnancy termination and perinatal outcomes in acute fatty liver of pregnancy (AFLP); however, the risks remain u...
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Article
Open AccessFunctional characterization of GmBZL2 (AtBZR1 like gene) reveals the conserved BR signaling regulation in Glycine max
Brassinosteroids (BRs) play key roles in plant growth and development, and regulate various agricultural traits. Enhanced BR signaling leads to increased seed number and yield in Arabidopsis bzr1-1D (AtBZR1P234L,...
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Article
Open AccessPrediction of phosphothreonine sites in human proteins by fusing different features
Phosphorylation is one of the most important protein post-translation modifications. With the rapid development of high-throughput mass spectrometry, phosphorylation site data is rapidly accumulating, which pr...
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Article
Open AccessGenomic and oncogenic preference of HBV integration in hepatocellular carcinoma
Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration detection and RNA sequencing, we ...
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Article
Open AccessErratum: Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma
Nature Communications 7: Article number: 12992 (2016); Published: 5 October 2016; Updated: 8 November 2016 The original version of this Article contained an error in the spelling of the author Tin-Lap Lee, whi...
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Article
Open AccessRealizing a facile and environmental-friendly fabrication of high-performance multi-crystalline silicon solar cells by employing ZnO nanostructures and an Al2O3 passivation layer
Nowadays, the multi-crystalline silicon (mc-Si) solar cells dominate the photovoltaic industry. However, the current acid etching method on mc-Si surface used by firms can hardly suppress the average reflectance ...
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Article
Open AccessPlant toxin β-ODAP activates integrin β1 and focal adhesion: A critical pathway to cause neurolathyrism
Neurolathyrism is a unique neurodegeneration disease caused by β-N-oxalyl-L-α, β- diaminopropionic (β-ODAP) present in grass pea seed (Lathyrus stativus L.) and its pathogenetic mechanism is unclear. This issue h...
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Article
Open AccessBilirubin augments Ca2+ load of develo** bushy neurons by targeting specific subtype of voltage-gated calcium channels
Neonatal brain is particularly vulnerable to pathological levels of bilirubin which elevates and overloads intracellular Ca2+, leading to neurotoxicity. However, how voltage-gated calcium channels (VGCCs) are fun...
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Open AccessCalcium ion regulation by BAPTA-AM and ruthenium red improved the fertilisation capacity and developmental ability of vitrified bovine oocytes
Vitrification reduces the fertilisation capacity and developmental ability of mammalian oocytes; this effect is closely associated with an abnormal increase of cytoplasmic free calcium ions ([Ca2+]i). However, li...
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Article
The relationship among serum lipocalin 2, bone turnover markers, and bone mineral density in outpatient women
We aimed to investigate associations among serum levels of LCN2, bone resorption marker carboxy-terminal cross-linking telopeptide of type-1 collagen (CTx), bone formation marker osteocalcin (OCN), and bone mi...
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Article
Open AccessmiR-27b regulates myogenic proliferation and differentiation by targeting Pax3 in goat
This study found that miR-27 is expressed in muscle and regulates muscle proliferation and differentiation. We explored the function and regulatory mechanism of miR-27b in goat muscle proliferation and differe...
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Open AccessImproved NO2 Gas Sensing Properties of Graphene Oxide Reduced by Two-beam-laser Interference
We report on the fabrication of a NO2 gas sensor from room-temperature reduction of graphene oxide(GO) via two-beam-laser interference (TBLI). The method of TBLI gives the distribution of periodic dissociation en...
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Article
Open AccessResveratrol significantly improves the fertilisation capacity of bovine sex-sorted semen by inhibiting apoptosis and lipid peroxidation
The aim of this study was to test the effects of five different concentrations (0, 10−3, 10−4, 10−5, and 10−6 M) of resveratrol (Res) supplementation in bull sperm washing and fertilisation medium on levels of re...
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Article
Open AccessRhodanine-based Knoevenagel reaction and ring-opening polymerization for efficiently constructing multicyclic polymers
Cyclic polymers have a number of unique physical properties compared with those of their linear counterparts. However, the methods for the synthesis of cyclic polymers are very limited, and some multicyclic po...
