6 Result(s)

Article

Osteocalcin ameliorates cognitive dysfunctions in a mouse model of Alzheimer’s Disease by reducing amyloid β burden and upregulating glycolysis in neuroglia

Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by the accumulation of amyloid β peptides (Aβ) and impaired glucose metabolism in the brain. Osteocalcin (OCN), an osteoblast...

Chang Shan, Deng Zhang, Dong-ni Ma, Yan-fang Hou, Qian-qian Zhuang… in Cell Death Discovery (2023)

Article

Correction to: BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis

**g-zun Xu, Yan-man Zhou, Lin-lin Zhang, **ao-**g Chen… in Cell Death Discovery (2022)

Article

Correction: FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3β-related pathways

Yan-Feng Huang, Wen-Bo Niu, Rong Hu, Ling-Jun Wang, Zeng-Yan Huang… in Oncogenesis (2022)

Article

BMP9 reduces age-related bone loss in mice by inhibiting osteoblast senescence through Smad1-Stat1-P21 axis

Age-related osteoporosis is characterized by the accumulation of senescent osteoblastic cells in bone microenvironment and significantly reduced osteogenic differentiation. Clearing of the senescent cells is h...

**g-zun Xu, Yan-man Zhou, Lin-lin Zhang, **ao-**g Chen… in Cell Death Discovery (2022)

Article

NLK is required for Ras/ERK/SRF/ELK signaling to tune skeletal muscle development by phosphorylating SRF and antagonizing the SRF/MKL pathway

Serum response factor (SRF) regulates differentiation and proliferation by binding to RhoA-actin-activated MKL or Ras-MAPK-activated ELK transcriptional coactivators, but the molecular mechanisms responsible f...

Shang-Ze Li, Ze-Yan Zhang, Jie Chen, Ming-You Dong, Xue-Hua Du… in Cell Death Discovery (2022)

Article

FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3β-related pathways

Colorectal cancer stem cells (CSCs), characterized by self-renewal ability and high expression of proliferative genes, contribute to the chemoresistance of colorectal cancer (CRC). We aimed to identify the mol...

Yan-Feng Huang, Wen-Bo Niu, Rong Hu, Ling-Jun Wang, Zeng-Yan Huang… in Oncogenesis (2018)