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The role of water channel proteins and nitric oxide signaling in rice seed germination
Previous studies have demonstrated the possible role of several aquaporins in seed germination. But systematic investigation of the role of aquaporin family members in this process is lacking. Here, the develo...
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Article
Is a new invasive herb emerging? Molecular confirmation and preliminary evaluation of natural hybridization between the invasive Sphagneticola trilobata (Asteraceae) and its native congener S. calendulacea in South China
Sphagneticola trilobata is an invasive herb in South China. Here, we reported some morphological intermediates between S. trilobata and the indigenous congener S. calendulacea in the field for th...
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Article
Open AccessA reporter gene system for screening inhibitors of Wnt signaling pathway
Abnormal activation of canonical Wnt signaling has been associated with various types of cancer. Inhibitory reagents targeting the Wnt signaling have great potential to inhibit the growth of relevant tumors. H...
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Article
Celastrol exerts synergistic effects with PHA-665752 and inhibits tumor growth of c-Met-deficient hepatocellular carcinoma in vivo
PHA665752 (PHA), a selective small molecule c-Met Inhibitor, potently inhibited HGF-stimulated and constitutive c-Met phosphorylation, as well as HGF and c-Met-driven phenotypes of a variety of tumor cells inc...
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Article
Development of InDel markers linked to Fusarium wilt resistance in cabbage
Cabbage Fusarium wilt (CFW) is a destructive disease causing great losses to cabbage (Brassica oleracea L. var. capitata L.) production worldwide. At present, there are few reports concerning molecular marker res...
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Breeding of cabbage (Brassica oleracea L. var. capitata) with fusarium wilt resistance based on microspore culture and marker-assisted selection
Cabbage Fusarium wilt (CFW), caused by Fusarium oxysporum f. sp. conglutinans, is one of the most devastating diseases of cabbage worldwide. In recent years, CFW has been spreading across northern Chinad. Thus, d...
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Article
Open AccessTranscriptome analysis of Panax vietnamensis var. fuscidicus discovers putative ocotillol-type ginsenosides biosynthesis genes and genetic markers
P. vietnamensis var. fuscidiscus, called “Yesanqi” in Chinese, is a new variety of P. vietnamensis, which was first found in **** County, the southern part of Yunnan Province, China. Compare...
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Article
Open AccessThe endophytic fungi of Salvia miltiorrhiza Bge.f. alba are a potential source of natural antioxidants
Salvia miltiorrhiza Bge. f. alba is a traditional Chinese herbal drug with special pharmacological effect on thromboangiitis obliterans. However, the nature source of S.miltiorrhiza Bge.f.alba is now in short sup...
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Article
Erratum to: Fungal diversity notes 111–252—taxonomic and phylogenetic contributions to fungal taxa
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Fungal diversity notes 111–252—taxonomic and phylogenetic contributions to fungal taxa
This paper is a compilation of notes on 142 fungal taxa, including five new families, 20 new genera, and 100 new species, representing a wide taxonomic and geographic range. The new families, Ascocylindricaceae,
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Article
Highly selective and efficient biotransformation of linarin to produce tilianin by naringinase
To develop a practical method to prepare tilianin by highly selective and efficient hydrolysis of the C-7 rhamnosyl group from linarin.
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Article
Sirtuin-3 (SIRT3) protects pancreatic β-cells from endoplasmic reticulum (ER) stress-induced apoptosis and dysfunction
Insufficient insulin produced by pancreatic β-cells in the control of blood sugar is a central feature of the etiology of diabetes. Reports have shown that endoplasmic reticulum (ER) stress is fundamentally in...
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Article
Distinct expression patterns of the GDP dissociation inhibitor protein gene (OsRhoGDI2) from Oryza sativa during development and abiotic stresses
Guanine nucleotide dissociation inhibitor (GDI) plays an essential role in regulating the forms of Rac/Rop between GDP-bound inactivity and GTP-bound activity in plants. In this paper, we reported a stress-res...
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Article
8′-epimer of herbicidin F and its congeners from Streptomyces sp. YIM 66142
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Article
Open AccessMicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion
Impaired synaptic plasticity and neuron loss are hallmarks of Alzheimer’s disease and vascular dementia. Here, we found that chronic brain hypoperfusion (CBH) by bilateral common carotid artery o...
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Open AccessA TBX5 3′UTR variant increases the risk of congenital heart disease in the Han Chinese population
TBX5 is a vital transcription factor involved in cardiac development in a dosage-dependent manner. But little is known about the potential association of TBX5 3′ untranslated region (UTR) variations with congenit...
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Article
Photosynthesis and growth responses of Fraxinus mandshurica Rupr. seedlings to a gradient of simulated nitrogen deposition
During an N-deposition simulation experiment, we showed that low to medium addition of N had beneficial effects on growth and photosynthetic rates of Fraxinus mandshurica Rupr. seedlings, whi...
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Open AccessPlumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling
Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers, and it requires novel treatment approaches and effective drugs. In the present study, we found that treatment with plumbagin, a natura...
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Article
Ca2+-CaMKKβ pathway is required for adiponectin-induced secretion in rat submandibular gland
Adiponectin functions as a promoter of saliva secretion in rat submandibular gland via activation of adenosine monophosphate-activated protein kinase (AMPK) and increased paracellular permeability. Ca2+ mobilizat...
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A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo
DNA origami-based nanorobot presents thrombin to cause tumor infarction after specific recognition of a tumor vessel marker.