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  1. No Access

    Article

    A 60-s postconditioning protocol by percutaneous coronary intervention inhibits myocardial apoptosis in patients with acute myocardial infarction

    Different postconditioning (Postcon) methods have been demonstrated to protect heart from ischemia/reperfusion injury. The relationship between Postcon by percutaneous coronary intervention (PCI) and apoptosis...

    Wen-Shu Zhao, Lin Xu, Le-Feng Wang, Li Zhang, Zhi-Yong Zhang, Yu Liu… in Apoptosis (2009)

  2. No Access

    Article

    Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells

    Increasing evidence has shown that a fraction of the wild-type (wt) form of the tumor suppressor p53, can translocate to mitochondria due to genotoxic stress. The mitochondrial targets of wt p53 have also been...

    Fei Wang, Jianfeng Liu, Delira Robbins, Kerri Morris, Amos Sit, Yong-Yu Liu… in Apoptosis (2011)

  3. No Access

    Article

    Albumin prevents reactive oxygen species-induced mitochondrial damage, autophagy, and apoptosis during serum starvation

    Aberrant levels of reactive oxygen species (ROS) rapidly generated from NADPH oxidase (NOX) activation can be cytotoxic due to activating pro-apoptotic signals. However, ROS also induce pro-survival autophagy ...

    Shu-Yu Liu, Chia-Ling Chen, Tsan-Tzu Yang, Wei-Ching Huang, Chia-Yuan Hsieh… in Apoptosis (2012)

  4. No Access

    Article

    Inhibition of 12/15 lipoxygenase by baicalein reduces myocardial ischemia/reperfusion injury via modulation of multiple signaling pathways

    12/15-Lipoxygenase (LOX) is a member of the LOX family that catalyzes the step from arachidonic acid to hydroxy-eicosatetraenoic acids (HETEs). Previous studies demonstrated that 12/15-LOX plays a critical rol...

    Lina Song, Hui Yang, Hong-**a Wang, Cui Tian, Yu Liu, **ang-Jun Zeng, Erhe Gao… in Apoptosis (2014)

  5. No Access

    Article

    AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis

    Angiogenic factor with G patch and FHA domains 1 (AGGF1) is a newly identified proangiogenic protein, which plays an important role in vascular disease and angiogenesis. However, its role in myocardial ischemi...

    Yu Liu, Hui Yang, Lina Song, Nan Li, Qiu-Yue Han, Cui Tian, Erhe Gao, Jie Du… in Apoptosis (2014)

  6. No Access

    Article

    The cardioprotective effect of salidroside against myocardial ischemia reperfusion injury in rats by inhibiting apoptosis and inflammation

    The main purpose of this study was to investigate effect of salidroside (Sal) on myocardial ischemia reperfusion injury in rats and the underlying mechanism. Myocardial ischemia reperfusion injury (MI/RI) mode...

    Lingpeng Zhu, Tingting Wei, ** Gao, **ayun Chang, He He, Fen Luo, Rui Zhou… in Apoptosis (2015)

  7. No Access

    Article

    Diallyl trisulfide ameliorates myocardial ischemia–reperfusion injury by reducing oxidative stress and endoplasmic reticulum stress-mediated apoptosis in type 1 diabetic rats: role of SIRT1 activation

    Diallyl trisulfide (DATS) protects against apoptosis during myocardial ischemia-reperfusion (MI/R) injury in diabetic state, although the underlying mechanisms remain poorly defined. Previously, we and others ...

    Liming Yu, Shu Li, **nlong Tang, Zhi Li, Jian Zhang, **aodong Xue, **song Han… in Apoptosis (2017)

  8. No Access

    Article

    Protodioscin ameliorates oxidative stress, inflammation and histology outcome in Complete Freund’s adjuvant induced arthritis rats

    Protective effect of protodioscin or methyl protodioscin against inflammation had been reported in various inflammation diseases. This study aimed to investigate the effect of protodioscin against Complete Fre...

    Jia-Yu Liu, Ya-Ling Hou, Rong Cao, Hong **a Qiu, Guo-Hua Cheng, Ran Tu… in Apoptosis (2017)

  9. Article

    Correction to: AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis

    Yu Liu, Hui Yang, Lina Song, Nan Li, Qiu-Yue Han, Cui Tian, Erhe Gao, Jie Du… in Apoptosis (2021)

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  10. No Access

    Article

    Ambra1 regulates apoptosis and chemosensitivity in breast cancer cells through the Akt-FoxO1-Bim pathway

    The sensitivity of cells to chemotherapeutic agents has a major effect on disease outcome in breast cancer patients. Unfortunately, there are numerous factors involved in the regulation of chemosensitivity, an...

    Wei-liang Sun, Ling-yan He, Li Liang, Si-yu Liu, Jie Luo, Mei-ling Lv… in Apoptosis (2022)

  11. No Access

    Article

    Ambra1 in cancer: implications for clinical oncology

    Activating molecule in Beclin-1-regulated autophagy protein 1 (Ambra1) is well known to mediate the autophagy process and promote the formation of autophagosomes. In addition, Ambra1 is involved in the executi...

    Yan-qiu Qin, Si-yu Liu, Mei-ling Lv, Wei-liang Sun in Apoptosis (2022)