120 Result(s)
within
**g Yu Liu
Life Sciences
Cell Biology
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Article
Involvement of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm
Cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP-activated chloride channel expressed in a wide variety of epithelial cells, mutations of which are responsible for the hallmark defective ch...
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Characterization of rtSH3p13 gene encoding a development protein involved in vesicular traffic in spermiogenesis
A cDNA, designated as rtSH3p13, was isolated from a rat testis cDNA library. It consists of 1463 bp nuclear acids, which encodes a protein of 312 amino acids and was assigned the GenBank accession number ...
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A new chromosome fluorescence banding technique combining DAPI staining with image analysis in plants
In this study, a new chromosome fluorescence banding technique was developed in plants. The technique combined 4′,6-diamidino-2-phenylindole (DAPI) staining with software analysis including three-dimensional i...
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Cx31 is assembled and trafficked to cell surface by ER-Golgi pathway and degraded by proteasomal or lysosomal pathways
Gap junctions, consisting of connexins, allow the exchange of small molecules (<1 kD) between adjacent cells, thus providing a mechanism for synchronizing the responses of groups of cells to environmental stim...
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Myosin X regulates netrin receptors and functions in axonal path-finding
Netrins regulate axon path-finding during development, but the underlying mechanisms are not well understood. Here, we provide evidence for the involvement of the unconventional myosin X (Myo X) in netrin-1 fu...
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Gene expression variation increase in trisomy 21 tissues
Congenital development disorders with variable severity occur in trisomy 21. However, how these phenotypic abnormalities develop with variations remains elusive. We hypothesize that the differences in euploid ...
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Article
Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B
Netrins, a family of secreted molecules, have critical functions in axon guidance and cell migration during neuronal development1,2. In addition to its role as a chemotropic molecule, netrin-1 also acts as a surv...
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The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling
Viral infection initiates a series of signaling cascades that activate the transcription factors nuclear factor kappa B and interferon regulatory factor 3, which collaborate to induce transcription of genes fo...
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Molecular analysis of a type III polyketide synthase gene in Fallopia multiflora
A type III polyketide synthase (PKS) cDNA and the corresponding gene (FmPKS) were isolated from the rhizomes of Fallopia multiflora (Thunb.) (Polygonaceae). The full-length FmPKS cDNA was 1,228 bp, containing an ...
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Article
Phytochelatin synthase of Thlaspi caerulescens enhanced tolerance and accumulation of heavy metals when expressed in yeast and tobacco
Phytochelatin synthase (PCS) is key enzyme for heavy metal detoxification and accumulation in plant. In this study, we isolated the PCS gene TcPCS1 from the hyperaccumulator Thlaspi caerulescens. Overexpression o...
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Astrocyte-like glia associated with the embryonic development of the central complex in the grasshopper Schistocerca gregaria
In this study we employed the expression of the astrocyte-specific enzyme glutamine synthetase, in addition to the glia-specific marker Repo, to characterize glia cell types associated with the embryonic devel...
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A cellular network of dye-coupled glia associated with the embryonic central complex in the grasshopper Schistocerca gregaria
The central complex of the grasshopper (Schistocerca gregaria) brain comprises a modular set of neuropils, which develops after mid-embryogenesis and is functional on hatching. Early in embryogenesis, Repo-positi...
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ApoE genotypes are associated with age at natural menopause in Chinese females
Ages at natural menarche and menopause are influenced by several genetic factors. This study aimed to investigate the possible relationship between the apolipoprotein E (ApoE) genotype and the age at menarche ...
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Effect of aging on islet beta-cell function and its mechanisms in Wistar rats
Type 2 diabetes mellitus is characterized by islet β-cell dysfunction and its incidence increases with age. However, the mechanisms underlying the effect of aging on islet β-cell function are not fully underst...
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Article
USP2a positively regulates TCR-induced NF-κB activation by bridging MALT1-TRAF6
The paracaspase MALT1 is essential for the activation of NF-κB in response to T cell receptor (TCR) stimulation. It recruits downstream TRAF6 and activates the E3 ligase activity of TRAF6 to polyubiquitinate s...
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Article
A Novel Peptide Can Mimic Extracellular Fibrinogen-Binding Protein to Block the Activation of Complement System
Extracellular fibrinogen-binding protein (Efb) of Staphylococcus aureus (S. aureus) is a bi-functional protein, which can specifically bind fibrinogen with its N terminus and inhibit deposition of C3b on the surf...
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Glia associated with central complex lineages in the embryonic brain of the grasshopper Schistocerca gregaria
We have investigated the pattern of glia associated with central complex lineages in the embryonic brain of the grasshopper Schistocerca gregaria. Using the glia-specific marker Repo, we identified glia associate...
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Article
Impaired autophagic function in rat islets with aging
Type 2 diabetes is characterized by a deficit in β-cell function and mass, and its incidence increases with age. Autophagy is a highly regulated intracellular process for degrading cytoplasmic components, part...
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Chondrogenic differentiation and three dimensional chondrogenesis of human adipose-derived stem cells induced by engineered cartilage-derived conditional media
Due to lack of optimal inductive protocols, how to effectively improve chondrogenesis of adiposederived stem cells (ASCs) is still a great challenge. Our previous studies demonstrated that the culture media de...
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Timelines in the insect brain: fates of identified neural stem cells generating the central complex in the grasshopper Schistocerca gregaria
This study employs labels for cell proliferation and cell death, as well as classical histology to examine the fates of all eight neural stem cells (neuroblasts) whose progeny generate the central complex of t...
