21 Result(s)

Article

Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC

Inflammasome activity is important for the immune response and is instrumental in numerous clinical conditions. Here we identify a mechanism that modulates the central Caspase-1 and NLR (Nod-like receptor) ada...

Danfeng Dong, Yuzhang Du, Xuefeng Fei, Hao Yang, **aofang Li… in Nature Communications (2023)

Article

A scATAC-seq atlas of chromatin accessibility in axolotl brain regions

Axolotl (Ambystoma mexicanum) is an excellent model for investigating regeneration, the interaction between regenerative and developmental processes, comparative genomics, and evolution. The brain, which serves a...

Weimin Feng, Shuai Liu, Qiuting Deng, Sulei Fu, Yunzhi Yang, ** Dai… in Scientific Data (2023)

Article

Author Correction: SpG and SpRY variants expand the CRISPR toolbox for genome editing in zebrafish

Fang Liang, Yu Zhang, Lin Li, Yexin Yang, Ji-Feng Fei, Yanmei Liu… in Nature Communications (2023)

Article

Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration

There are major differences in duration and scale at which limb development and regeneration proceed, raising the question to what extent regeneration is a recapitulation of development. We address this by ana...

Marketa Kaucka, Alberto Joven Araus, Marketa Tesarova… in Nature Communications (2022)

Article

Construction of the axolotl cell landscape using combinatorial hybridization sequencing at single-cell resolution

The Mexican axolotl (Ambystoma mexicanum) is a well-established tetrapod model for regeneration and developmental studies. Remarkably, neotenic axolotls may undergo metamorphosis, a process that triggers many dra...

Fang Ye, Guodong Zhang, Weigao E., Haide Chen, Chengxuan Yu… in Nature Communications (2022)

Article

SpG and SpRY variants expand the CRISPR toolbox for genome editing in zebrafish

Precise genetic modifications in model organisms are essential for biomedical research. The recent development of PAM-less base editors makes it possible to assess the functional impact and pathogenicity of nu...

Fang Liang, Yu Zhang, Lin Li, Yexin Yang, Ji-Feng Fei, Yanmei Liu… in Nature Communications (2022)

Article

Serum ErbB2 concentration positively correlated to the glycemic variations in newly diagnosed Type 2 diabetic patients

Evidences indicate that elevated levels of circulating ErbB2 are closely associated with increased incidence of diabetes. However, the relationship between ErbB2 concentration and glycemic variations (GV) in t...

Yan Huang, **a Han, Ting Chang, Feng-fei Li, Xuan Chen, Yu-qing She in Scientific Reports (2022)

Article

Author Correction: EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Lingling Jiang, Yingying Shen, Danfeng Guo, Diya Yang, Jiajun Liu… in Nature Communications (2020)

Article

Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse

Orderly chromosome segregation is enabled by crossovers between homologous chromosomes in the first meiotic division. Crossovers arise from recombination-mediated repair of programmed DNA double-strand breaks ...

Anastasiia Bondarieva, Kavya Raveendran, Vladyslav Telychko… in Nature Communications (2020)

Article

Author Correction: The axolotl genome and the evolution of key tissue formation regulators

In the originally published version of this Article, the sequenced axolotl strain (the homozygous white mutant) was denoted as ‘D/D’ rather than ‘d/d’ in Fig. 1a and the accompanying legend, the main text and ...

Sergej Nowoshilow, Siegfried Schloissnig, Ji-Feng Fei, Andreas Dahl… in Nature (2018)

Article

Metformin add-on continuous subcutaneous insulin infusion on precise insulin doses in patients with type 2 diabetes

To investigate whether metformin add-on to the continuous subcutaneous insulin infusion (Met + CSII) therapy leads to a significant reduction in insulin doses required by type 2 diabetes (T2D) patients to main...

Feng-fei Li, Bing-li Liu, Guo-** Yin, Reng-na Yan, Dan-feng Zhang… in Scientific Reports (2018)

Article

Management of glycemic variation in diabetic patients receiving parenteral nutrition by continuous subcutaneous insulin infusion (CSII) therapy

To compare the continuous subcutaneous insulin infusion (CSII) or insulin glargine based multiple injections (MDI) therapy on glycemic variations in diabetic patients receiving PN outside of intensive care set...

Feng-fei Li, Wen-li Zhang, Bing-li Liu, Dan-feng Zhang, Wei Chen… in Scientific Reports (2018)

Article

The axolotl genome and the evolution of key tissue formation regulators

Salamanders serve as important tetrapod models for developmental, regeneration and evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma mexicanum) a key representative salaman...

Sergej Nowoshilow, Siegfried Schloissnig, Ji-Feng Fei, Andreas Dahl… in Nature (2018)

Article

Young onset type 2 diabetic patients might be more sensitive to metformin compared to late onset type 2 diabetic patients

It is unknown whether YOD (young onset diabetes) and LOD (late onset diabetes) require similar insulin doses for intensive insulin therapy with a metformin add-on to achieve glycemic control. We analyzed data ...

Feng-fei Li, Bing-li Liu, Guo-** Yin, Dan-feng Zhang… in Scientific Reports (2017)

Article

Correction: Corrigendum: EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance

Nature Communications 7: Article number: 13045 (2016); Published: 10 October 2016; Updated: 14 June 2017 This Article contains an error in Fig. 8a, for which we apologize. In Fig. 8a, the control 3 image for p...

Lingling Jiang, Yingying Shen, Danfeng Guo, Diya Yang, Jiajun Liu… in Nature Communications (2017)

Article

Improving Spatiotemporal Breast Cancer Assessment and Prediction in Hangzhou City, China

Breast cancer (BC) is the main cause of death of female cancer patients in China. Mainstream map** techniques, like spatiotemporal ordinary kriging (STOK), generate disease incidence maps that improve our un...

Zhaohan Lou, Xufeng Fei, George Christakos, Jianbo Yan, Jia** Wu in Scientific Reports (2017)

Article

Features of glycemic variations in drug naïve type 2 diabetic patients with different HbA_1c values

To define the features of glycemic variations in drug naïve type 2 diabetic (T2D) patients with different HbA_1c values using continuous glucose monitoring (CGM), a total of 195 drug naïve T2D patients were admitt...

Feng-fei Li, Bing-li Liu, Reng-na Yan, Hong-hong Zhu, Pei-hua Zhou… in Scientific Reports (2017)

Article

EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance

How the intestinal tract develops a tolerance to foreign antigens is still largely unknown. Here we report that extracellular vesicles (EVs) with TGF-β1-dependent immunosuppressive activity are produced by int...

Lingling Jiang, Yingying Shen, Danfeng Guo, Diya Yang, Jiajun Liu… in Nature Communications (2016)

Article

Direct TEM observations of growth mechanisms of two-dimensional MoS₂ flakes

A microscopic understanding of the growth mechanism of two-dimensional materials is of particular importance for controllable synthesis of functional nanostructures. Because of the lack of direct and insightfu...

Linfeng Fei, Shui** Lei, Wei-Bing Zhang, Wei Lu, Ziyuan Lin… in Nature Communications (2016)

Article

Spatiotemporal Co-existence of Female Thyroid and Breast Cancers in Hangzhou, China

Thyroid and breast cancers (TC, BC) are common female malignant tumors worldwide. Studies suggest that TC patients have a higher BC risk, and vice versa. However, it has not been investigated quantitatively if...

Xufeng Fei, George Christakos, Zhaohan Lou, Yanjun Ren, Qingmin Liu… in Scientific Reports (2016)