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DNMT1 driven by mouse amniotic fluid mesenchymal stem cell exosomes improved corneal cryoinjury via inducing microRNA-33 promoter DNA hypermethylation modification in corneal epithelium cells
Severe corneal cryoinjury can cause permanent corneal swelling and bullous keratopathy, one of the main reason for loss of sight. Mouse amniotic fluid mesenchymal stem cells (mAF-MSCs) can repair corneal damag...
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Article
Open AccessStructural Engineering of Anode Materials for Low-Temperature Lithium-Ion Batteries: Mechanisms, Strategies, and Prospects
The working principles and limitations of current anode materials at low temperatures are elucidated.
Advantages and emphas...
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Article
Open AccessInflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC
Inflammasome activity is important for the immune response and is instrumental in numerous clinical conditions. Here we identify a mechanism that modulates the central Caspase-1 and NLR (Nod-like receptor) ada...
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Article
Open AccessA scATAC-seq atlas of chromatin accessibility in axolotl brain regions
Axolotl (Ambystoma mexicanum) is an excellent model for investigating regeneration, the interaction between regenerative and developmental processes, comparative genomics, and evolution. The brain, which serves a...
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Article
Influence of diamine moieties on the gas permeation performances of polyimide: perspectives from experiment and simulation
This work reported the gas permeation performances of three 6FDA-based polyimides, including 6FDA-DABA, 6FDA-ODA and 6FDA-TFDB, which contain polar amide, flexible ether, and bulky –CF3 groups in diamine units, r...
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Article
Scale optimization of urban agglomerations based on the connection strength between cities under the framework of sustainable development
Sustainable development is a common goal across the world. As the core force to promote economic growth and enhance national competitiveness, the sustainable development of urban agglomeration is a key compone...
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Article
Contamination and Health Risk Assessment of Heavy Metal Pollution in Soils Developed from Different Soil Parent Materials
Accurate risk assessment of heavy metal pollution in soil is a prerequisite for environmental and human health protection. Due to the spatial heterogeneity in the environment, biased results can be obtained wh...
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Article
Growth of single-crystal black phosphorus and its alloy films through sustained feedstock release
Black phosphorus (BP), a fascinating semiconductor with high mobility and a tunable direct bandgap, has emerged as a candidate beyond traditional silicon-based devices for next-generation electronics and optoe...
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Article
Open AccessAuthor Correction: SpG and SpRY variants expand the CRISPR toolbox for genome editing in zebrafish
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Chapter
Explore the Project of Smart Education to Promote Teacher Professional Development
Since its establishment in 2012, Lantian Road Primary School in Bengbu has always been actively exploring smart education with “building smart campus as a paradise for teachers and students” as school manageme...
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Applying a Knock-In Strategy to Create Reporter-Tagged Knockout Alleles in Axolotls
Tetrapod species axolotls exhibit the powerful capacity to fully regenerate their tail and limbs upon injury, hence serving as an excellent model organism in regenerative biology research. Develo** proper mo...
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Article
Open AccessAltered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration
There are major differences in duration and scale at which limb development and regeneration proceed, raising the question to what extent regeneration is a recapitulation of development. We address this by ana...
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Article
Open AccessA cluster of mesopontine GABAergic neurons suppresses REM sleep and curbs cataplexy
Physiological rapid eye movement (REM) sleep termination is vital for initiating non-REM (NREM) sleep or arousal, whereas the suppression of excessive REM sleep is promising in treating narcolepsy. However, th...
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Article
Open AccessSynergistic strain engineering of perovskite single crystals for highly stable and sensitive X-ray detectors with low-bias imaging and monitoring
Although three-dimensional metal halide perovskite (ABX3) single crystals are promising next-generation materials for radiation detection, state-of-the-art perovskite X-ray detectors include methylammonium as A-s...
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Article
Open AccessConstruction of the axolotl cell landscape using combinatorial hybridization sequencing at single-cell resolution
The Mexican axolotl (Ambystoma mexicanum) is a well-established tetrapod model for regeneration and developmental studies. Remarkably, neotenic axolotls may undergo metamorphosis, a process that triggers many dra...
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Article
Open AccessRegulatory roles of alternative splicing at Ezh2 gene in mouse oocytes
Enhancer of zeste homologue 2 (EZH2), the core member of polycomb repressive complex 2 (PRC2), has multiple splicing modes and performs various physiological functions. However, function and mechanism of alte...
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Article
Estimating the spatial distribution of soil available trace elements by combining auxiliary soil property data through the Bayesian maximum entropy technique
Trace elements are essential nutrients for plant growth. An accurate prediction of soil available trace elements is necessary for scientifically based fertilization and soil environmental protection. In total,...
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Article
Open AccessSpG and SpRY variants expand the CRISPR toolbox for genome editing in zebrafish
Precise genetic modifications in model organisms are essential for biomedical research. The recent development of PAM-less base editors makes it possible to assess the functional impact and pathogenicity of nu...
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Article
Retraction Note: Overexpression of CAV3 facilitates bone formation via the Wnt signaling pathway in osteoporotic rats
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Article
Letter to the editor regarding “Predictors for second-stage posterior direct decompression after lateral lumbar interbody fusion: a review of five hundred fifty-seven patients in the past five years”
