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  1. Article

    Open Access

    Telomere-to-telomere Citrullus super-pangenome provides direction for watermelon breeding

    To decipher the genetic diversity within the cucurbit genus Citrullus, we generated telomere-to-telomere (T2T) assemblies of 27 distinct genotypes, encompassing all seven Citrullus species. This T2T super-pangeno...

    Yilin Zhang, Mingxia Zhao, **gsheng Tan, Minghan Huang, **ao Chu… in Nature Genetics (2024)

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  2. No Access

    Article

    Transforming toxins into treatments: the revolutionary role of α-amanitin in cancer therapy

    Amanita phalloides is the primary species responsible for fatal mushroom poisoning, as its main toxin, α-amanitin, irreversibly and potently inhibits eukaryotic RNA polymerase II (RNAP II), leading to cell death....

    Deyuan Ning, **fang Xue, **ran Lou, Ruifei Shao, Yu Liu… in Archives of Toxicology (2024)

  3. No Access

    Article

    Highly stable, stretchable, and transparent electrodes based on dual-headed Ag@Au core-sheath nanomatchsticks for non-enzymatic glucose biosensor

    Stretchable and transparent electrodes (STEs) based on silver nanowires (AgNWs) have garnered considerable attention due to their unique optoelectronic features. However, the low oxidation resistance of AgNWs ...

    Yangyang Wang, **gyi Kong, Ruifang Xue, Jian** Wang, Min Gong… in Nano Research (2023)

  4. No Access

    Article

    Mechanism and treatment of α-amanitin poisoning

    Amanita poisoning has a high mortality rate. The α-amanitin toxin in Amanita is the main lethal toxin. There is no specific detoxification drug for α-amanitin, and the clinical treatment mainly focuses on symp...

    **fang Xue, **ran Lou, Deyuan Ning, Ruifei Shao, Guobing Chen in Archives of Toxicology (2023)

  5. Article

    Open Access

    An automated COVID-19 triage pipeline using artificial intelligence based on chest radiographs and clinical data

    While COVID-19 diagnosis and prognosis artificial intelligence models exist, very few can be implemented for practical use given their high risk of bias. We aimed to develop a diagnosis model that addresses no...

    Chris K. Kim, Ji Whae Choi, Zhicheng Jiao, Dongcui Wang, **g Wu… in npj Digital Medicine (2022)

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  6. Article

    Open Access

    Optimizing the timing of diagnostic testing after positive findings in lung cancer screening: a proof of concept radiomics study

    The timeliness of diagnostic testing after positive screening remains suboptimal because of limited evidence and methodology, leading to delayed diagnosis of lung cancer and over-examination. We propose a radi...

    Zixing Wang, Ning Li, Fuling Zheng, **n Sui, Wei Han… in Journal of Translational Medicine (2021)

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  7. Article

    Open Access

    Is exposure to tobacco associated with extrahepatic cholangiocarcinoma epidemics? A retrospective proportional mortality study in China

    Extrahepatic cholangiocarcinoma (ECC) has become one of the most rapidly increasing malignancies in China during recent decades. The relationship between tobacco exposure and ECC epidemics is unclear; this stu...

    Lei Hou, **gmei Jiang, Boqi Liu, Wei Han, Yan** Wu, **aonong Zou, Fang Xue… in BMC Cancer (2019)

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  8. No Access

    Article

    Effects of active, passive, and combined smoking on cervical cancer mortality: a nationwide proportional mortality study in Chinese urban women

    To determine whether smoking, in any form, is a risk factor in the development of cervical cancer (CC) among urban Chinese women.

    **gmei Jiang, Haiyu Pang, Boqi Liu, Philip C. Nasca, Biao Zhang… in Cancer Causes & Control (2015)