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**chang Chen
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Article
Open AccessPedigree analysis exploring the inconsistency between diverse phenotypes and testing criteria for germline TP53 mutations in Chinese women with breast cancer
In the present study, we addressed the inconsistency between the testing criteria and diverse phenotypes for germline TP53 mutation in patients with breast cancer in the Chinese population.
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Resveratrol ameliorates cyprodinil-induced zebrafish cardiac developmental defects as an aryl hydrocarbon receptor antagonist
Cyprodinil, a globally utilized broad-spectrum pyrimidine amine fungicide, has been observed to elicit cardiac abnormality. Resveratrol (RSV), a naturally occurring polyphenolic compound, showcases remarkable ...
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Article
Robotic versus laparoscopic pelvic lateral lymph node dissection in locally advanced rectal cancer: a systemic review and meta-analysis
There are few available studies that compare the feasibility, efficacy, and safety of robotic pelvic lateral lymph node dissection compared to laparoscopic pelvic lateral lymph node dissection (LPLND) in advan...
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Extracellular histones promote TWIK2-dependent potassium efflux and associated NLRP3 activation in alveolar macrophages during sepsis-induced lung injury
Sepsis-induced acute lung injury (ALI) is a complex and life-threatening condition lacking specific and efficient clinical treatments. Extracellular histones, identified as a novel type of damage-associated mo...
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Asking alternative identity for help: how and why the multiple-identity perspective impacts compensatory consumption behavior
Experiences of negative self-discrepancies can give rise to threats to one’s identity, thus increasing or decreasing approach behaviors directed toward the primed identity. Although previous researchers have i...
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Open AccessLearning and depicting lobe-based radiomics feature for COPD Severity staging in low-dose CT images
Chronic obstructive pulmonary disease (COPD) is a prevalent and debilitating respiratory condition that imposes a significant healthcare burden worldwide. Accurate staging of COPD severity is crucial for patie...
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Open AccessContactless vital signs monitoring in macaques using a mm-wave FMCW radar
Heart rate (HR) and respiration rate (RR) play an important role in the study of complex behaviors and their physiological correlations in non-human primates (NHPs). However, collecting HR and RR information i...
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Open AccessPlasma 25-hydroxyvitamin D deficiency in the peri-operative period is associated with survival outcome in colorectal cancer patients: a meta-analysis
Surgery had a significant impact on 25-hydroxyvitamin D (25-(OH)D) levels. Uncertainty still existed regarding the effects of peri-operative 25(OH)D deficiency on colorectal cancer (CRC) patients’ prognosis. T...
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Open AccessQuorum sensing gene lasR promotes phage vB_Pae_PLY infection in Pseudomonas aeruginosa
Quorum sensing (QS) is a cell density-based intercellular communication system that controls virulence gene expression and biofilm formation. In Pseudomonas aeruginosa (P. aeruginosa), the LasR system sits at the...
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Article
Gambling culture, corporate risk preference and bond risk premium
In this paper, utilizing the Chinese context, we investigate whether and how the regional gambling culture affects bond risk premiums. Using a lottery-based measure of the local gambling culture, our empirical...
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Open AccessImpact of Online Video Game-Based Dichoptic Training on Binocular Vision Rehabilitation in Post-surgical Patients with Intermittent Exotropia
Dichoptic training has emerged as a promising rehabilitation approach for improving binocular visual function in patients with strabismus. A prospective observational study design was employed to assess the ef...
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Synthesis of hollow platelet polymer particles by spontaneous precision fragmentation
The creation of anisotropic core–shell nanoparticles using the living crystallization-driven self-assembly method results in colloidally stable solid particles. The fragmentation or degradation of crystallizat...
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Open AccessIFI16 promotes the progression of clear cell renal cell carcinoma through the IL6/PI3K/AKT axis
Clear cell renal cell carcinoma (ccRCC) is a common disease in the urinary system, with a high incidence and poor prognosis in advanced stages. Although γ-interferon-inducible protein 16 (IFI16) has been repor...
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Anthraquinone/activated carbon electrochemical sensor and its application in acetaminophen analysis
Acetaminophen (AC) can inhibit the synthesis of prostaglandins in the body, and has antipyretic and analgesic effects. In this paper, a two-step microwave impregnation method was used to prepare anthraquinone ...
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Article
Depth distribution and depth adaptation of microbiomes in juvenile and adult scleractinian corals (Pocillopora verrucosa) in the central South China Sea
Environmental conditions at different water depths on tropical atolls are substantially different, but few studies have investigated the depth distribution and adaptation in the microbiomes of juvenile and adu...
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Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis
Severe asthma, characterized by inflammation and airway remodeling, involves fibroblast differentiation into myofibroblasts expressing α-SMA. This process leads to the production of fibronectin and connective ...
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COPD stage detection: leveraging the auto-metric graph neural network with inspiratory and expiratory chest CT images
Chronic obstructive pulmonary disease (COPD) is a common lung disease that can lead to restricted airflow and respiratory problems, causing a significant health, economic, and social burden. Detecting the COPD...
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A novel nomogram integrated with preablation stimulated thyroglobulin and thyroglobulin/thyroid-stimulating hormone ratio to predict the therapeutic response of intermediate‑ and high‑risk differentiated thyroid cancer patients: a bi-center retrospective study
To investigate the factors influencing the outcome of radioactive iodine (RAI) treatment in intermediate- to high-risk patients with differentiated thyroid carcinoma (DTC).
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Article
Resonance Analysis in a High-Rise Building: Combined Translational and Rotational Measurements
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GSNOR negatively regulates the NLRP3 inflammasome via S-nitrosation of MAPK14
Hyperactivation of the NLRP3 inflammasome has been implicated in the pathogenesis of numerous diseases. However, the precise molecular mechanisms that modulate the transcriptional regulation of NLRP3 remain large...
