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Article
Open AccessMulti-objective Bayesian active learning for MeV-ultrafast electron diffraction
Ultrafast electron diffraction using MeV energy beams(MeV-UED) has enabled unprecedented scientific opportunities in the study of ultrafast structural dynamics in a variety of gas, liquid and solid state syste...
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Article
Open AccessResearch on trajectory control technology for L-shaped horizontal exploration wells in coalbed methane
Horizontal wells have significant advantages in coal bed methane exploration and development blocks. However, its application in new exploration and development blocks could be challenging. Limited geological ...
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Article
Open AccessExploring the effects of AI literacy in teacher learning: an empirical study
As most practitioners (including teachers) do not know how AI functions and cannot make full use of AI in education, there is an urgent need to investigate teachers’ intentions to learn AI and related determin...
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Article
Open AccessSystematic investigation of chemo-immunotherapy synergism to shift anti-PD-1 resistance in cancer
Chemo-immunotherapy combinations have been regarded as one of the most practical ways to improve immunotherapy response in cancer patients. In this study, we integrate the transcriptomics data from anti-PD-1-t...
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Open AccessExpression of USP25 associates with fibrosis, inflammation and metabolism changes in IgG4-related disease
IgG4-related disease (IgG4-RD) has complex clinical manifestations ranging from fibrosis and inflammation to deregulated metabolism. The molecular mechanisms underpinning these phenotypes are unclear. In this ...
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Open AccessMap** the urban and rural planning response paths to pandemics of infectious diseases
Modern urban and rural planning has a long history in terms of epidemics. However, contemporary urban and rural planning lacks a comprehensive response map for the prevention and control of infectious diseases...
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Article
Open AccessCan green finance policy promote ecosystem product value realization? Evidence from a quasi-natural experiment in China
This study takes the Green Finance Pilot Zones (GFPZ) policy in China as a quasi-natural experiment and employs the synthetic control method to test the policy effect of GFPZ on ecosystem product value realiza...
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Open AccessA dicarbonate solvent electrolyte for high performance 5 V-Class Lithium-based batteries
Rechargeable lithium batteries using 5 V positive electrode materials can deliver considerably higher energy density as compared to state-of-the-art lithium-ion batteries. However, their development remains pl...
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Article
Open AccessInhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy
The multifaceted chemo-immune resistance is the principal barrier to achieving cure in cancer patients. Identifying a target that is critically involved in chemo-immune-resistance represents an attractive stra...
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Open AccessAnalysis of audiological outcomes of children referred from a universal newborn hearing screening program over 9 years in Bei**g, China
Universal newborn hearing screening (UNHS) and audiological diagnosis are crucial for children with congenital hearing loss (HL). The objective of this study was to analyze hearing screening techniques, audiol...
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Article
Open AccessGlobal transcontinental power pools for low-carbon electricity
The transition to low-carbon electricity is crucial for meeting global climate goals. However, given the uneven spatial distribution and temporal variability of renewable resources, balancing the supply and de...
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Open AccessPrecise synthesis and photovoltaic properties of giant molecule acceptors
Series of giant molecule acceptors DY, TY and QY with two, three and four small molecule acceptor subunits are synthesized by a stepwise synthetic method and used for systematically investigating the influence...
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Article
Open AccessLocal control of superconductivity in a NbSe2/CrSBr van der Waals heterostructure
Two-dimensional magnets and superconductors are emerging as tunable building-blocks for quantum computing and superconducting spintronic devices, and have been used to fabricate all two-dimensional versions of...
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Article
Cascaded compression of size distribution of nanopores in monolayer graphene
Monolayer graphene with nanometre-scale pores, atomically thin thickness and remarkable mechanical properties provides wide-ranging opportunities for applications in ion and molecular separations1, energy storage
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Open AccessAuthor Correction: Ultrafast non-radiative dynamics of atomically thin MoSe2
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Spin-mediated shear oscillators in a van der Waals antiferromagnet
Understanding how microscopic spin configuration gives rise to exotic properties at the macroscopic length scale has long been pursued in magnetic materials1–5. One seminal example is the Einstein–de Haas effect ...
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Article
Open AccessFunctional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates
Delivering genes to and across the brain vasculature efficiently and specifically across species remains a critical challenge for addressing neurological diseases. We have evolved adeno-associated virus (AAV9)...
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Article
Open AccessGIS model for geothermal advantageous target selection
As the particularly popular green energy, geothermal resources are gradually favored by countries around the world, and the development model centered on geothermal dew point cannot meet the increasing geother...
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Open AccessWhole-genome sequencing identifies potential candidate genes for egg production traits in laying ducks (Anas platyrhynchos)
Egg production traits are economically important in laying ducks. Genetic molecular mechanisms and candidate genes underlying these traits remain unclear. In this study, whole genome variants were identified t...
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Open AccessCRISPR-based targeted haplotype-resolved assembly of a megabase region
Constructing high-quality haplotype-resolved genome assemblies has substantially improved the ability to detect and characterize genetic variants. A targeted approach providing readily access to the rich infor...