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  1. Article

    Open Access

    RBPsuite: RNA-protein binding sites prediction suite based on deep learning

    RNA-binding proteins (RBPs) play crucial roles in various biological processes. Deep learning-based methods have been demonstrated powerful on predicting RBP sites on RNAs. However, the training of deep learni...

    **aoyong Pan, Yi Fang, **anfeng Li, Yang Yang, Hong-Bin Shen in BMC Genomics (2020)

  2. No Access

    Article

    Identification of the copy number variant biomarkers for breast cancer subtypes

    Breast cancer is a common and threatening malignant disease with multiple biological and clinical subtypes. It can be categorized into subtypes of luminal A, luminal B, Her2 positive, and basal-like. Copy numb...

    **aoyong Pan, **aoHua Hu, Yu-Hang Zhang, Lei Chen in Molecular Genetics and Genomics (2019)

  3. Article

    Open Access

    Prediction of RNA-protein sequence and structure binding preferences using deep convolutional and recurrent neural networks

    RNA regulation is significantly dependent on its binding protein partner, known as the RNA-binding proteins (RBPs). Unfortunately, the binding preferences for most RBPs are still not well characterized. Interd...

    **aoyong Pan, Peter Rijnbeek, Junchi Yan, Hong-Bin Shen in BMC Genomics (2018)

  4. No Access

    Article

    Discriminating cirRNAs from other lncRNAs using a hierarchical extreme learning machine (H-ELM) algorithm with feature selection

    As non-coding RNAs, circular RNAs (cirRNAs) and long non-coding RNAs (lncRNAs) have attracted an increasing amount of attention. They have been confirmed to participate in many biological processes, including ...

    Lei Chen, Yu-Hang Zhang, Guohua Huang, **aoyong Pan in Molecular Genetics and Genomics (2018)

  5. Article

    Open Access

    IPMiner: hidden ncRNA-protein interaction sequential pattern mining with stacked autoencoder for accurate computational prediction

    Non-coding RNAs (ncRNAs) play crucial roles in many biological processes, such as post-transcription of gene regulation. ncRNAs mainly function through interaction with RNA binding proteins (RBPs). To understa...

    **aoyong Pan, Yong-**an Fan, Junchi Yan, Hong-Bin Shen in BMC Genomics (2016)