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Article
Open AccessHeat shock protein 90α reduces CD8+ T cell exhaustion in acute lung injury induced by lipopolysaccharide
CD8+ T-cell exhaustion is a promising prognostic indicator of sepsis-induced acute respiratory distress syndrome (ARDS). Patients with sepsis-related ARDS had reduced levels of HSP90AA1. However, whether the chan...
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Article
The Single-Ended Protection of Flexible HVDC Transmission Line Based on Traveling Wave Power Amplitude Ratios Using S-Transform
The fast and reliable protection is one key technology of flexible HVDC transmission system. The traditional flexible DC line protection is mainly based on single-ended fault characteristics, whose reliability...
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Article
Open AccessA decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection
Acute type A aortic dissection (AAAD) is a devastating disease. Human aortic smooth muscle cells (HASMCs) exhibit decreased proliferation and increased apoptosis, and integrin α5β1 and FAK are important proang...
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Article
Open AccessEu-MOF-Based Fluorescent Ratiometric Sensor by Detecting 3,4,5-Trihydroxybenzoic for Fingerprint Visualization on Porous Objects
Latent fingerprints (LFPs) at the crime scene are served as important clues to locate the trajectory of criminal behavior and portray the characteristics of the suspect. Therefore, visualizing LFPs is of consi...
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Article
A signal-off photoelectrochemical sandwich-type immunosensor based on WO3/TiO2 Z-scheme heterojunction
A sandwich “signal-off” type photoelectrochemical (PEC) immunosensor was fabricated based on a composite heterojunction of tungsten oxide/titanium oxide microspheres (WO3/TiO2) acting as signal amplification pla...
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Article
Open AccessPECSS: Pulmonary Embolism Comprehensive Screening Score to safely rule out pulmonary embolism among suspected patients presenting to emergency department
Pulmonary embolism is a severe cardiovascular disease and can be life-threatening if left untreated. However, the detection rate of pulmonary embolism using existing pretest probability scores remained relativ...
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Article
Open AccessRole of CD8+ T cell exhaustion in the progression and prognosis of acute respiratory distress syndrome induced by sepsis: a prospective observational study
CD8+ T cells are important for protective immunity against intracellular pathogens. Excessive amounts of antigen and/or inflammatory signals often lead to the gradual deterioration of CD8+ T cell function, a stat...
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Article
Open AccessAlbumin alleviated esketamine-induced neuronal apoptosis of rat retina through downregulation of Zn2+-dependent matrix metalloproteinase 9 during the early development
Esketamine upregulates Zn2+-dependent matrix metalloproteinase 9 (MMP9) and increases the neuronal apoptosis in retinal ganglion cell layer during the early development. We aimed to test whether albumin can allev...
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Article
Development and validation of a novel nomogram for postoperative pulmonary complications following minimally invasive esophageal cancer surgery
Postoperative pulmonary complications (PPCs) are the most common complications following minimally invasive esophagectomy (MIE) and can be associated with adverse outcomes. This study aims to construct a nomog...
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Article
Open AccessThe pathogens of secondary infection in septic patients share a similar genotype to those that predominate in the gut
Secondary nosocomial infections, which are commonly caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) and vancomycin-resistant Enterococcus faecium (VRE), often develop in septic patients. This study ai...
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Article
A highly sensitive electrochemiluminescence method for abrin detection by a portable biosensor based on a screen-printed electrode with a phage display affibody as specific labeled probe
Abrin is a highly toxic ribosome-inactivating protein, which could be used as a biological warfare agent and terrorist weapon, and thus needs to be detected efficiently and accurately. Affibodies are a new cla...
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Article
Causes, Risk Factors and Outcomes of Patients Readmitted to the Intensive Care Unit After Esophageal Cancer Surgery: A Retrospective Cohort Study
Readmission to intensive care unit (ICU) after esophageal cancer surgery is a major concern and can be associated with increased adverse outcomes. This study aims to explore causes, risk factors and early outc...
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Chapter and Conference Paper
A Self-adaptive Method for Identifying the Last Circuit Breakers in Hybrid AC/DC Power Grids
The last circuit breaker (LCB) is the key circuit breaker in the hybrid AC/DC power grids for avoiding severe overvoltage of AC/DC equipment caused by LCBs trip**. A self-adaptive LCBs identification scheme ...
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Article
Open AccessClinical characteristics, risk factors, immune status and prognosis of secondary infection of sepsis: a retrospective observational study
Secondary infection has a higher incidence in septic patients and affects clinical outcomes. This study aims to investigate the clinical characteristics, risk factors, immune status and prognosis of secondary ...
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Article
Open AccessGpr174-deficient regulatory T cells decrease cytokine storm in septic mice
G protein-coupled receptor 174 (GPR174) is mainly expressed in thymus, spleen, lymph nodes, and leukocytes, and genetic variation in GPR174 is associated with susceptibility to autoimmune diseases, indicating tha...
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Article
Open AccessUnified optimal power flow model for AC/DC grids integrated with natural gas systems considering gas-supply uncertainties
A unified optimal power flow (OPF) model for AC/DC grids integrated with natural gas systems is proposed for the real-time scheduling of power systems. Herein, the primary physical couplings underlying this co...
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Chapter and Conference Paper
Reconfigurable Compliant Unit Modeling and Compositions
This paper proposes a configuration changement method for the generation of the compliant units as compliant configuration building block. With the FEM analysis of the compliant properties, the compliant chara...
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Article
Open AccessDiagnostic and prognostic utility of tissue factor for severe sepsis and sepsis-induced acute lung injury
Tissue factor (TF) and tissue factor pathway inhibitor (TFPI) play a central role in the endothelial permeability regulation and dysfunction, which is associated with the development of sepsis and acute lung i...
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Article
Open AccessGenetic variation in the tissue factor gene is associated with clinical outcome in severe sepsis patients
Activation of inflammation and coagulation was closely related and mutually interdependent in sepsis. Tissue factor (TF) and its endogenous inhibitor, tissue factor pathway inhibitor (TFPI) was the main regula...
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Article
Open AccessGenetic variation in the TNF receptor-associated factor 6 gene is associated with susceptibility to sepsis-induced acute lung injury
Recent studies showed that overwhelming inflammatory response mediated by the toll-like receptor (TLR)-related pathway was important in the development of acute lung injury (ALI). The aim of this study was to ...
