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Article
Effect of Shear Angle on Microstructure and Mechanical Properties of AZ61 Mg Alloy During Extrusion-Shear Process
To enhance the strength and plasticity of the AZ61 Mg alloy, a process called extrusion-shear (ES) was proposed. The process is based on conventional extrusion with the addition of two equal extrusion channels...
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Article
Effect of Pre-homogenization Treatment on Microstructure, Mechanical Properties, and Corrosion Resistance of Hot Extruded AZ61 Magnesium Alloy
This paper studied the microstructure, mechanical properties, and corrosion resistance of AZ61 magnesium (Mg) alloy with and without homogenization treatment before extrusion. After homogenization treatment, t...
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Article
Computational modeling and simulation of bioinspired nacre-like composites
Inspired by design motifs driving the balanced combination of rigidity, strength, and toughness in biological materials, this paper presents 3D computational modeling and simulation of an interface-enriched hy...
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Article
Hierarchically porous carbon with pentagon defects as highly efficient catalyst for oxygen reduction and oxygen evolution reactions
Highly dispersed electrocatalysts and single-atom catalysts receive extensive attention in the field of multiple reactions involving water spitting, oxygen reduction, and CO2 reduction. Herein, we develop a Fe/N ...
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Article
Surface modification of paclitaxel-loaded tri-block copolymer PLGA-b-PEG-b-PLGA nanoparticles with protamine for liver cancer therapy
In order to enhance the therapeutic effect of chemotherapy on liver cancer, a biodegradable formulation of protamine-modified paclitaxel-loaded poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co
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Article
Doxorubicin-loaded star-shaped copolymer PLGA-vitamin E TPGS nanoparticles for lung cancer therapy
A doxorubicin-loaded mannitol-functionalized poly(lactide-co-glycolide)-b-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles (DOX-loaded M-PLGA-b-TPGS NPs) were prepared by a modified nanoprecipitat...
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Article
Open AccessSurface modification of TPGS-b-(PCL-ran-PGA) nanoparticles with polyethyleneimine as a co-delivery system of TRAIL and endostatin for cervical cancer gene therapy
The efficient delivery of therapeutic genes into cells of interest is a critical challenge to broad application of non-viral vector systems. In this research, a novel TPGS-b-(PCL-ran-PGA) nanoparticle modified wi...
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Article
Modeling and Simulation of Soft Contact and Adhesion of Stem Cells
In this paper, we briefly report our recent work on multiscale modeling and simulations of soft elasticity and focal adhesion of stem cells. In particular, our work is focused on modeling and simulation of con...
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Article
Open AccessOral Delivery of DMAB-Modified Docetaxel-Loaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy
Three types of nanoparticle formulation from biodegradable PLGA-TPGS random copolymer were developed in this research for oral administration of anticancer drugs, which include DMAB-modified PLGA nanoparticles...