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7 Result(s)

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  1. Article

    Open Access

    Mitochondria-associated endoplasmic reticulum membrane (MAM): a dark horse for diabetic cardiomyopathy treatment

    Diabetic cardiomyopathy (DCM), an important complication of diabetes mellitus (DM), is one of the most serious chronic heart diseases and has become a major cause of heart failure worldwide. At present, the pa...

    Yong Liu, **-Ling Huo, Kaidi Ren, Shaokang Pan, Hengdao Liu… in Cell Death Discovery (2024)

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  2. Article

    Open Access

    Diabetic cardiomyopathy: Early diagnostic biomarkers, pathogenetic mechanisms, and therapeutic interventions

    Diabetic cardiomyopathy (DCM) mainly refers to myocardial metabolic dysfunction caused by high glucose, and hyperglycemia is an independent risk factor for cardiac function in the absence of coronary atheroscl...

    **-Ling Huo, Qi Feng, Shaokang Pan, Wen-Jia Fu, Zhangsuo Liu… in Cell Death Discovery (2023)

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  3. Article

    Open Access

    The Road from AKI to CKD: Molecular Mechanisms and Therapeutic Targets of Ferroptosis

    Acute kidney injury (AKI) is a prevalent pathological condition that is characterized by a precipitous decline in renal function. In recent years, a growing body of studies have demonstrated that renal maladap...

    Runzhi Guo, Jiayu Duan, Shaokang Pan, Fei Cheng, Ying** Qiao… in Cell Death & Disease (2023)

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  4. Article

    Open Access

    HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis

    Diabetic nephropathy (DN) is a serious complication in type 1 and type 2 diabetes, and renal interstitial fibrosis plays a key role in DN progression. Here, we aimed to probe into the role and potential mechan...

    DongWei Liu, FengXun Liu, ZhengYong Li, ShaoKang Pan, JunWei **e… in Cell Death & Disease (2021)

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  5. Article

    Open Access

    Concise review: current trends on applications of stem cells in diabetic nephropathy

    Diabetic nephropathy, with high prevalence, is the main cause of renal failure in diabetic patients. The strategies for treating DN are limited with not only high cost but an unsatisfied effect. Therefore, the...

    Dongwei Liu, Wen Zheng, Shaokang Pan, Zhangsuo Liu in Cell Death & Disease (2020)

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  6. No Access

    Article

    Domain view: a web tool for protein domain visualization and analysis

    The identification of sequence-based protein domains and their boundaries is often a prelude to structure determination. An accurate prediction of disordered regions, secondary structures and low complexity se...

    **aokang Pan, Craig A. Bingman… in Journal of Structural and Functional Genom… (2010)

  7. No Access

    Article

    A graphical approach to tracking and reporting target status in structural genomics

    Determination of a protein structure requires a series of decisions and processes, starting with target selection, through cloning, expression, purification, and finally structure determination. Structural gen...

    **aokang Pan, Gary E. Wesenberg… in Journal of Structural and Functional Genom… (2007)