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Metformin-induced changes of the gut microbiota in patients with type 2 diabetes mellitus: results from a prospective cohort study

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  1. Article

    Open Access

    Heavy metal poisoning caused by Chinese folk remedies in psoriasis patients: a retrospective analysis

    Psoriasis, characterized as a chronic relapsing disease with a protracted course, often drives patients to seek relief through Chinese folk remedies (CFR). Nonetheless, the complex compositions of these remedi...

    Changjiang Xue, Xuqin Du, **aoli Zhu, Na Wu, Qiao Ye in Scientific Reports (2024)

  2. Article

    Open Access

    Electrochemically coupled CH4 and CO2 consumption driven by microbial processes

    The chemical transformations of methane (CH4) and carbon dioxide (CO2) greenhouse gases typically have high energy barriers. Here we present an approach of strategic coupling of CH4 oxidation and CO2 reduction in...

    Yue Zheng, Huan Wang, Yan Liu, Peiyu Liu, Baoli Zhu, Yanning Zheng in Nature Communications (2024)

  3. Article

    Open Access

    The reproduction process of Gram-positive protocells

    Protocells are believed to have existed on early Earth prior to the emergence of prokaryotes. Due to their rudimentary nature, it is widely accepted that these protocells lacked intracellular mechanisms to reg...

    Dheeraj Kanaparthi, Marko Lampe, Jan-Hagen Krohn, Baoli Zhu in Scientific Reports (2024)

  4. Article

    Open Access

    Lifestyle patterns influence the composition of the gut microbiome in a healthy Chinese population

    High-throughput sequencing allows for the comprehensive analysis of the human intestinal microbiota. However, extensive association analyses between the microbiome and lifestyle differences in the Chinese popu...

    Yi Ren, Jiawei Wu, Yilin Wang, Lanying Zhang, **g Ren, Zhiming Zhang in Scientific Reports (2023)

  5. Article

    Open Access

    Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice

    In mammals, the production of mature oocytes necessitates rigorous regulation of the discontinuous meiotic cell-cycle progression at both the transcriptional and post-transcriptional levels. However, the facto...

    Xue Jiang, Yu Cheng, Yuzhang Zhu, Caoling Xu, Qiaodan Li in Nature Communications (2023)

  6. Article

    Open Access

    Deep learning to automatically evaluate HER2 gene amplification status from fluorescence in situ hybridization images

    Human epidermal growth factor receptor 2 (HER2) gene amplification helps identify breast cancer patients who may respond to targeted anti-HER2 therapy. This study aims to develop an automated method for quanti...

    Tian Xue, Heng Chang, Min Ren, Haochen Wang, Yu Yang, Boyang Wang in Scientific Reports (2023)

  7. Article

    Open Access

    The interactive effects of extreme temperatures and PM2.5 pollution on mortalities in Jiangsu Province, China

    Exposure to extreme temperatures or fine particles is associated with adverse health outcomes but their interactive effects remain unclear. We aimed to explore the interactions of extreme temperatures and PM2.5 p...

    Lian Zhou, Yuning Wang, Qingqing Wang, Zhen Ding, Hui **, Ting Zhang in Scientific Reports (2023)

  8. Article

    Open Access

    Throwing and manipulating and cheating with a DNA nano-dice

    Artificial molecular machines have captured the imagination of researchers, given their clear potential to mimic and influence human life. Key to behavior simulation is to reproduce the specific properties of ...

    **aochen Tang, Tianshu Chen, Wenxing Li, Dongsheng Mao in Nature Communications (2023)

  9. Article

    Open Access

    Effects of short-term PM2.5 exposure on blood lipids among 197,957 people in eastern China

    Globally, air pollution is amongst the most significant causes of premature death. Nevertheless, studies on the relationship between fine particulate matter (PM2.5) exposure and blood lipids have typically not be...

    Qiao Liu, Zhan Wang, Junjie Lu, Zhongqi Li, Leonardo Martinez in Scientific Reports (2023)

  10. Article

    Open Access

    Lantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer

    mRNA delivery has shown high application value in the treatment of various diseases, but its effective delivery is still a major challenge at present. Herein, we propose a lantern-shaped flexible RNA origami f...

    Muren Hu, Chang Feng, Qianqin Yuan, Chenbin Liu, Bujun Ge in Nature Communications (2023)

  11. Article

    Open Access

    Nitrogen use aggravates bacterial diversity and network complexity responses to temperature

    Rising temperature affects microbial composition and function in agriculture field, especially under nitrogen fertilization. In this study, we investigated the bacterial community of paddy soil incubated at co...

    **aoyi **ng, Huifang Xu, Dou Wang, **anjun Yang, Hongling Qin in Scientific Reports (2022)

  12. Article

    Open Access

    CircSLC8A1 and circNFIX can be used as auxiliary diagnostic markers for sudden cardiac death caused by acute ischemic heart disease

    Sudden cardiac death (SCD) caused by acute ischemic heart disease (IHD) is a major cause of sudden death worldwide. Circular RNAs (circRNAs) are abundant in the heart and play important roles in cardiovascular...

    Meihui Tian, Jiajia Xue, Cuiyun Dai, Enzhu Jiang, Baoli Zhu, Hao Pang in Scientific Reports (2021)

  13. Article

    Open Access

    Potential role of endoplasmic reticulum stress is involved in the protection of fish oil on neonatal rats with necrotizing enterocolitis

    Neonatal necrotizing enterocolitis (NEC) is a serious gastrointestinal disease with high death rate in premature infants. Fish oil (FO) and its constituents have been shown to ameliorate intestinal inflammatio...

    **aoli Zhu, Ningxun Cui, Lingling Yu, ** Cheng, Mingling Cui in Scientific Reports (2020)

  14. Article

    Open Access

    Publisher Correction: Epidemiological characteristics of pesticide poisoning in Jiangsu Province, China, from 2007 to 2016

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Ning Wang, Qingtao Jiang, Lei Han, Hengdong Zhang, Baoli Zhu, **n Liu in Scientific Reports (2020)

  15. Article

    Open Access

    The Influence of Occupational Noise Exposure on Cardiovascular and Hearing Conditions among Industrial Workers

    This study was conducted to estimate the current prevalence of hypertension, cardiovascular condition and hearing difficulty of workers exposure to occupational noise, and to analyze any associations between t...

    **uting Li, Qiu Dong, Boshen Wang, Haiyan Song, Shizhi Wang in Scientific Reports (2019)

  16. Article

    Open Access

    Epidemiological characteristics of pesticide poisoning in Jiangsu Province, China, from 2007 to 2016

    To investigate the characteristics of pesticide poisoning in Jiangsu province and provide a scientific basis for measures for the prevention of pesticide poisoning. Information from pesticide poisoning report ...

    Ning Wang, Qingtao Jiang, Lei Han, Hengdong Zhang, Baoli Zhu, **n Liu in Scientific Reports (2019)

  17. Article

    Open Access

    The bile salt glycocholate induces global changes in gene and protein expression and activates virulence in enterotoxigenic Escherichia coli

    Pathogenic bacteria use specific host factors to modulate virulence and stress responses during infection. We found previously that the host factor bile and the bile component glyco-conjugated cholate (NaGCH, ...

    Enrique Joffre, Matilda Nicklasson, Sandra Álvarez-Carretero in Scientific Reports (2019)

  18. Article

    Open Access

    DNMT1 and DNMT3A haplotypes associated with noise-induced hearing loss in Chinese workers

    This study was conducted to explore the effects of DNMT1 and DNMT3A polymorphisms on susceptibility to noise-induced hearing loss (NIHL) in Chinese workers. A total of 2689 industrial workers from a single textil...

    Enmin Ding, **g Liu, Haoran Guo, Huanxi Shen, Hengdong Zhang in Scientific Reports (2018)

  19. Article

    Open Access

    Author Correction: A novel quantitative PCR mediated by high-fidelity DNA polymerase

    A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

    Mengling Zhang, Kyle Liu, Yihong Hu, Yi Lin, Yang Li, ** Zhong in Scientific Reports (2018)

  20. Article

    Open Access

    MiR-92a and miR-486 are potential diagnostic biomarkers for mercury poisoning and jointly sustain NF-κB activity in mercury toxicity

    Occupational and environmental exposure to mercury is a public health concern worldwide. Although the altered epigenetic regulatory features, such as microRNA, have been associated with mercury exposure, the u...

    Enmin Ding, Jun Guo, Ying Bai, Hengdong Zhang, **n Liu, Wenyan Cai in Scientific Reports (2017)

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