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Open AccessHeavy metal poisoning caused by Chinese folk remedies in psoriasis patients: a retrospective analysis
Psoriasis, characterized as a chronic relapsing disease with a protracted course, often drives patients to seek relief through Chinese folk remedies (CFR). Nonetheless, the complex compositions of these remedi...
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Article
Open AccessElectrochemically coupled CH4 and CO2 consumption driven by microbial processes
The chemical transformations of methane (CH4) and carbon dioxide (CO2) greenhouse gases typically have high energy barriers. Here we present an approach of strategic coupling of CH4 oxidation and CO2 reduction in...
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Article
Open AccessThe reproduction process of Gram-positive protocells
Protocells are believed to have existed on early Earth prior to the emergence of prokaryotes. Due to their rudimentary nature, it is widely accepted that these protocells lacked intracellular mechanisms to reg...
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Open AccessLifestyle patterns influence the composition of the gut microbiome in a healthy Chinese population
High-throughput sequencing allows for the comprehensive analysis of the human intestinal microbiota. However, extensive association analyses between the microbiome and lifestyle differences in the Chinese popu...
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Article
Open AccessMaternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice
In mammals, the production of mature oocytes necessitates rigorous regulation of the discontinuous meiotic cell-cycle progression at both the transcriptional and post-transcriptional levels. However, the facto...
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Open AccessDeep learning to automatically evaluate HER2 gene amplification status from fluorescence in situ hybridization images
Human epidermal growth factor receptor 2 (HER2) gene amplification helps identify breast cancer patients who may respond to targeted anti-HER2 therapy. This study aims to develop an automated method for quanti...
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Open AccessThe interactive effects of extreme temperatures and PM2.5 pollution on mortalities in Jiangsu Province, China
Exposure to extreme temperatures or fine particles is associated with adverse health outcomes but their interactive effects remain unclear. We aimed to explore the interactions of extreme temperatures and PM2.5 p...
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Article
Open AccessThrowing and manipulating and cheating with a DNA nano-dice
Artificial molecular machines have captured the imagination of researchers, given their clear potential to mimic and influence human life. Key to behavior simulation is to reproduce the specific properties of ...
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Article
Open AccessEffects of short-term PM2.5 exposure on blood lipids among 197,957 people in eastern China
Globally, air pollution is amongst the most significant causes of premature death. Nevertheless, studies on the relationship between fine particulate matter (PM2.5) exposure and blood lipids have typically not be...
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Article
Open AccessLantern-shaped flexible RNA origami for Smad4 mRNA delivery and growth suppression of colorectal cancer
mRNA delivery has shown high application value in the treatment of various diseases, but its effective delivery is still a major challenge at present. Herein, we propose a lantern-shaped flexible RNA origami f...
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Article
Open AccessNitrogen use aggravates bacterial diversity and network complexity responses to temperature
Rising temperature affects microbial composition and function in agriculture field, especially under nitrogen fertilization. In this study, we investigated the bacterial community of paddy soil incubated at co...
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Open AccessCircSLC8A1 and circNFIX can be used as auxiliary diagnostic markers for sudden cardiac death caused by acute ischemic heart disease
Sudden cardiac death (SCD) caused by acute ischemic heart disease (IHD) is a major cause of sudden death worldwide. Circular RNAs (circRNAs) are abundant in the heart and play important roles in cardiovascular...
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Article
Open AccessPotential role of endoplasmic reticulum stress is involved in the protection of fish oil on neonatal rats with necrotizing enterocolitis
Neonatal necrotizing enterocolitis (NEC) is a serious gastrointestinal disease with high death rate in premature infants. Fish oil (FO) and its constituents have been shown to ameliorate intestinal inflammatio...
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Open AccessPublisher Correction: Epidemiological characteristics of pesticide poisoning in Jiangsu Province, China, from 2007 to 2016
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessThe Influence of Occupational Noise Exposure on Cardiovascular and Hearing Conditions among Industrial Workers
This study was conducted to estimate the current prevalence of hypertension, cardiovascular condition and hearing difficulty of workers exposure to occupational noise, and to analyze any associations between t...
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Open AccessEpidemiological characteristics of pesticide poisoning in Jiangsu Province, China, from 2007 to 2016
To investigate the characteristics of pesticide poisoning in Jiangsu province and provide a scientific basis for measures for the prevention of pesticide poisoning. Information from pesticide poisoning report ...
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Open AccessThe bile salt glycocholate induces global changes in gene and protein expression and activates virulence in enterotoxigenic Escherichia coli
Pathogenic bacteria use specific host factors to modulate virulence and stress responses during infection. We found previously that the host factor bile and the bile component glyco-conjugated cholate (NaGCH, ...
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Open AccessDNMT1 and DNMT3A haplotypes associated with noise-induced hearing loss in Chinese workers
This study was conducted to explore the effects of DNMT1 and DNMT3A polymorphisms on susceptibility to noise-induced hearing loss (NIHL) in Chinese workers. A total of 2689 industrial workers from a single textil...
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Open AccessAuthor Correction: A novel quantitative PCR mediated by high-fidelity DNA polymerase
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
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Article
Open AccessMiR-92a and miR-486 are potential diagnostic biomarkers for mercury poisoning and jointly sustain NF-κB activity in mercury toxicity
Occupational and environmental exposure to mercury is a public health concern worldwide. Although the altered epigenetic regulatory features, such as microRNA, have been associated with mercury exposure, the u...