16 Result(s)
within
**aoJie Chen
Life Sciences
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Article
Restoration of degraded alpine meadows from the perspective of plant–soil feedbacks
Understanding the plant–soil feedbacks (PSFs) of dominant species of alpine meadow under different degradation status could provide insights into sustainable restoration. The direction, strength, and influenci...
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Article
Deletion of the cheZ gene results in the loss of swimming ability and the decrease of adhesion ability to Caco-2 cells in Escherichia coli Nissle 1917
The aim of this study was to elucidate the biological functions of the motility regulatory protein CheZ in the probiotic strain Escherichia coli Nissle 1917. A cheZ gene deletion strain Nissle 1917ΔcheZ was const...
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Correction to: Niche differentiation and higher uptake of available nitrogen maintained the productivity of alpine meadow at early degradation
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Niche differentiation and higher uptake of available nitrogen maintained the productivity of alpine meadow at early degradation
A short-term in situ 15 N labeling experiment was conducted to investigate whether the N uptake and preference for different forms of available soil N for dominant plant species and soil microorganisms relate to ...
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Open AccessNon-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7
Drug resistance is responsible for castration-resistant prostate cancer (CRPC)-associated mortality. While ATP binding cassette subfamily C member 5 (ABCC5) has been reported to regulate multiple drug resistan...
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Open AccessCorrection: Myocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy
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Open AccessHyperChIP: identification of hypervariable signals across ChIP-seq or ATAC-seq samples
Identifying genomic regions with hypervariable ChIP-seq or ATAC-seq signals across given samples is essential for large-scale epigenetic studies. In particular, the hypervariable regions across tumors from dif...
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Open AccessMyocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy
Upon vascular injury, vascular smooth muscle cells (VSMCs) change from a contractile phenotype to a synthetic phenotype, thereby leading to atherogenesis and arterial restenosis. Myocardin (MYOCD) is essential...
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Article
CDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway
Colorectal cancer (CRC) is the third most diagnosed cancer and the second leading cause of cancer-related deaths. However, there are few effective therapeutic targets for CRC patients. Here, we found that CDK1...
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Mesenchymal stem cells: ideal seeds for treating diseases
Mesenchymal stem cells (MSCs), a kind of multipotent stem cells with self-renewal ability and multi-differentiation ability, have become the “practical stem cells” for the treatment of diseases. MSCs have immu...
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Open AccessA systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks
Lung adenocarcinoma (LUAD) is a highly malignant and heterogeneous tumor that involves various oncogenic genetic alterations. Epigenetic processes play important roles in lung cancer development. However, the ...
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Open AccessMicroRNA-320d regulates tumor growth and invasion by promoting FoxM1 and predicts poor outcome in gastric cardiac adenocarcinoma
Recent evidences demonstrate that dysregulated expression of microRNA-320d (miR-320d) has been associated with several cancer development and progression. However the effect of miR-320d on gastric cardiac aden...
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Open AccessAntifungal activity of volatile compounds produced by endophytic Bacillus subtilis DZSY21 against Curvularia lunata
To screen endophytic Bacillus producing volatile organic compounds (VOCs) with antifungal activity, and to explore their biocontrol properties toward the growth and pathogenicity of Curvularia lunata.
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Article
Open AccessBehavioral heterogeneity in quorum sensing can stabilize social cooperation in microbial populations
Microbial communities are susceptible to the public goods dilemma, whereby individuals can gain an advantage within a group by utilizing, but not sharing the cost of producing, public goods. In bacteria, the d...
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Effect of dietary prickly ash (Zanthoxylum bungeanum) seeds (PAS) on growth, body composition, and health of juvenile Jian carp (Cyprinus carpio var. Jian)
Prickly ash seed (PAS) is composed of 27–31 % lipids and may be a potential lipid-rich ingredient for fish feed. In this study, we examined how the supplementation of four isonitrogenous (31.44 %) and isocalor...
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Article
Open AccessExpression of Wnt and Notch signaling pathways in inflammatory bowel disease treated with mesenchymal stem cell transplantation: evaluation in a rat model
The purpose of this study was to investigate the expression of Wnt and Notch signaling pathway-related genes in inflammatory bowel disease (IBD) treated with mesenchymal stem cell transplantation (MSCT).
