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Exploring the active components and potential mechanisms of Alpiniae oxyphyllae Fructus in treating diabetes mellitus with depression by UPLC-Q-Exactive Orbitrap/MS, network pharmacology and molecular docking

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  1. Article

    Open Access

    Fully automated assessment of the future liver remnant in a blood-free setting via CT before major hepatectomy via deep learning

    To develop and validate a deep learning (DL) model for automated segmentation of hepatic and portal veins, and apply the model in blood-free future liver remnant (FLR) assessments via CT before major hepatectomy.

    Tingting **e, **gyu Zhou, **aodong Zhang, Yaofeng Zhang in Insights into Imaging (2024)

  2. Article

    Open Access

    Comprehensive analysis of the expression, prognostic, and immune infiltration for COL4s in stomach adenocarcinoma

    Collagen (COL) genes, play a key role in tumor invasion and metastasis, are involved in tumor extracellular matrix (ECM)-receptor interactions and focal adhesion pathways. However, studies focusing on the diag...

    Ying Xu, Hangbin **, Yan Chen, Zhen Yang, Dongchao Xu in BMC Medical Genomics (2024)

  3. Article

    Open Access

    The value of IL-6, PCT, qSOFA, NEWS, and SIRS to predict septic shock after Percutaneous nephrolithotomy

    There are numerous methods available for predicting sepsis following Percutaneous Nephrolithotomy. This study aims to compare the predictive value of Quick Sequential Organ Failure Assessment (qSOFA), Systemic...

    Yuxin Liu, Qihao Sun, Houtao Long, Zhijian Qiu, Daofeng Zhang, Haiyang Zhang in BMC Urology (2024)

  4. Article

    Open Access

    Media frames and images of Chinese immigrants: analyzing European newspaper narratives from 2015 to 2022

    The influx of Chinese immigrants into Europe has spawned varied media frames, sha** public perceptions and attitudes towards this demographic. The portrayal of Chinese immigrants in European newspapers has b...

    Hao Gao, Li Peng, **aofeng Zhang in Humanities and Social Sciences Communications (2024)

  5. Article

    Correction to: Preparation of Plasma Sprayed GDC Electrolytes for Metal-Supported Solid Oxide Fuel Cells

    Mengting Zhang, Chen Song, Kaisheng Lin, Min Liu in Journal of Thermal Spray Technology (2024)

  6. Article

    Open Access

    Structural insights into human exon-defined spliceosome prior to activation

    Spliceosome is often assembled across an exon and undergoes rearrangement to span a neighboring intron. Most states of the intron-defined spliceosome have been structurally characterized. However, the structur...

    Wenyu Zhang, **aofeng Zhang, **echao Zhan, Rui Bai, Jianlin Lei in Cell Research (2024)

  7. Article

    Open Access

    Single-atom nanozymes shines diagnostics of gastrointestinal diseases

    Various clinical symptoms of digestive system, such as infectious, inflammatory, and malignant disorders, have a profound impact on the quality of life and overall health of patients. Therefore, the chase for ...

    Sijia Hua, **ulin Dong, Qiuxia Peng, Kun Zhang in Journal of Nanobiotechnology (2024)

  8. Article

    Open Access

    Construction and validation of a novel tumor morphology immune inflammatory nutritional score (TIIN score) for intrahepatic cholangiocarcinoma: a multicenter study

    Tumor morphology, immune function, inflammatory levels, and nutritional status play critical roles in the progression of intrahepatic cholangiocarcinoma (ICC). This multicenter study aimed to investigate the a...

    Haofeng Zhang, Guan Huang, Qingshan Li, Yanbo Wang, Zhenwei Yang, Pengyu Chen in BMC Cancer (2024)

  9. Article

    Open Access

    Ferroptosis exacerbates hyperlipidemic acute pancreatitis by enhancing lipid peroxidation and modulating the immune microenvironment

    Abnormal activation of ferroptosis worsens the severity of acute pancreatitis and intensifies the inflammatory response and organ damage, but the detailed underlying mechanisms are unknown. Compared with other...

    **nyi Gu, Zhicheng Huang, **uzhiye Ying, **aodie Liu, Kaiyi Ruan in Cell Death Discovery (2024)

  10. Article

    Open Access

    Efficacy and safety of robotic versus laparoscopic liver resection for hepatocellular carcinoma: a propensity score-matched retrospective cohort study

    Evidence concerning long-term outcome of robotic liver resection (RLR) and laparoscopic liver resection (LLR) for hepatocellular carcinoma (HCC) patients is scarce.

    He Li, Lingzhan Meng, Simiao Yu, Haocheng Zheng, Lingxiang Yu in Hepatology International (2024)

  11. Article

    Open Access

    A dynamic prediction model of landslide displacement based on VMD–SSO–LSTM approach

    Addressing the limitations of existing landslide displacement prediction models in capturing the dynamic characteristics of data changes, this study introduces a novel dynamic displacement prediction model for...

    Haiying Wang, Yang Ao, Chenguang Wang, Yingzhi Zhang, **aofeng Zhang in Scientific Reports (2024)

  12. Article

    Open Access

    Mechanistic study on the alleviation of postmenopausal osteoporosis by Lactobacillus acidophilus through butyrate-mediated inhibition of osteoclast activity

    In China, traditional medications for osteoporosis have significant side effects, low compliance, and high costs, making it urgent to explore new treatment options. Probiotics have demonstrated superiority in ...

    Junjie Dong, Guizhao Shu, ** Yang, Bing Wang, Lingqiang Chen in Scientific Reports (2024)

  13. Article

    Open Access

    PlaqueNet: deep learning enabled coronary artery plaque segmentation from coronary computed tomography angiography

    Cardiovascular disease, primarily caused by atherosclerotic plaque formation, is a significant health concern. The early detection of these plaques is crucial for targeted therapies and reducing the risk of ca...

    Linyuan Wang, **aofeng Zhang, Congyu Tian in Visual Computing for Industry, Biomedicine… (2024)

  14. Article

    Open Access

    Exploring the effect of different typical plant community on human stress reduction: a field experiment

    Research has demonstrated the positive effect of natural environment on human restoration and well-being. Time spent in nature can often alleviate both physiological and psychological stress. However, few stud...

    Wenfei Yao, Qingzi Luo, **aofeng Zhang, Chen Zhuo, Longfei Mi in Scientific Reports (2024)

  15. Article

    Open Access

    Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin

    Hemorrhagic toxin (TcsH) is a major virulence factor produced by Paeniclostridium sordellii, which is a non-negligible threat to women undergoing childbirth or abortions. Recently, Transmembrane Serine Protease 2...

    Ruoyu Zhou, Liuqing He, Jiahao Zhang, **aofeng Zhang, Yanyan Li in Nature Communications (2024)

  16. Article

    Open Access

    M2 Microglia-Derived Exosomes Protect Against Glutamate-Induced HT22 Cell Injury via Exosomal miR-124-3p

    As one of the most serious complications of sepsis, sepsis-associated encephalopathy has not been effectively treated or prevented. Exosomes, as a new therapeutic method, play a protective role in neurodegener...

    Lan Zhu, Limei Ma, **n Du, Yuhao Jiang, Jiake Gao, Zihao Fan in Molecular Neurobiology (2024)

  17. Article

    Open Access

    Changes in the characteristics and outcomes of high-risk pregnant women who delivered prior to and after China’s universal two-child policy: a real-world retrospective study, 2010–2021

    In 2016, the “universal two-child” policy, allowing each couple to have two children, was introduced in China. The characteristic change of the long-term period after the implementation of the universal two-ch...

    Caixia Zhu, Shaofeng Zhang, Lixia Shen, Lisha Ye, Min** Zhan in BMC Public Health (2024)

  18. Article

    Open Access

    Combination of clinical information and radiomics models for the differentiation of acute simple appendicitis and non simple appendicitis on CT images

    To investigate the radiomics models for the differentiation of simple and non-simple acute appendicitis. This study retrospectively included 334 appendectomy cases (76 simple and 258 non-simple cases) for acut...

    Yinming Zhao, **n Wang, Yaofeng Zhang, Tao Liu, Shuai Zuo, Lie Sun in Scientific Reports (2024)

  19. Article

    Open Access

    The usefulness of contrast echocardiography in the evaluation of cardiac masses: a multicenter study

    Cardiac masses can encompass a variety of conditions, such as tumors, thrombi, vegetations, calcific lesions, and other rare diseases. Treatment and management of these types of cardiac masses differ considera...

    Qingtao Wang, Bing Wang, **aofeng Zhang, **n Zhong in BMC Cardiovascular Disorders (2024)

  20. Article

    Open Access

    Predictive value of HTS grade in patients with intrahepatic cholangiocarcinoma undergoing radical resection: a multicenter study from China

    Intrahepatic cholangiocarcinoma (ICC) is a highly malignant tumor with a poor prognosis. This study aimed to investigate whether Hemoglobin, Albumin, Lymphocytes, and Platelets (HALP) score and Tumor Burden Sc...

    Guan Huang, Haofeng Zhang, Zhenwei Yang, Qingshan Li in World Journal of Surgical Oncology (2024)

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