6 Result(s)
within
**ao-wan Wang
Neurosciences
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Article
Open AccessKCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice
Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood. Here, we found that chronic constructive injury (CCI) in mi...
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Article
Open AccessArginine is neuroprotective through suppressing HIF-1α/LDHA-mediated inflammatory response after cerebral ischemia/reperfusion injury
Neuroinflammation is a secondary response following ischemia stroke. Arginine is a non-essential amino acid that has been shown to inhibit acute inflammatory reaction. In this study we show that arginine treat...
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Article
Open AccessTRPV1 mediates astrocyte activation and interleukin-1β release induced by hypoxic ischemia (HI)
Hypoxic-ischemic encephalopathy (HIE) is a serious birth complication with high incidence in both advanced and develo** countries. Children surviving from HIE often have severe long-term sequela including ce...
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Article
Open Access25th Annual Computational Neuroscience Meeting: CNS-2016
A1 Functional advantages of cell-type heterogeneity in neural circuits
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Article
Open AccessIntra-hippocampal administration of ZIP alleviates depressive and anxiety-like responses in an animal model of posttraumatic stress disorder
Given that impairment of fear extinction has been implicated in the pathogenesis of posttraumatic stress disorder (PTSD), effective pharmacological interventions that facilitate fear extinction may provide alt...
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Article
Open AccessOverweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation
Apoptosis, neuroinflammation and blood-brain barrier (BBB) damage affect the susceptibility of the develo** brain to hypoxic-ischemic (HI) insults. c-Jun N-terminal kinase (JNK) is an important mediator of i...
