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  1. No Access

    Article

    pp5644 Interacts with phosphatidylinositol-4-phosphate adaptor protein-1 associated protein-1

    The human novel gene pp5644 (GeneBank Accession No. AF289559) coding for 124 amino acids was recently cloned. Overexpression of pp5644 in Hela cells significantly inhibited the growth and colony formation. The pp...

    **ao-**a Ye, Hong Lu, Yao Yu, Ning Ding… in Molecular and Cellular Biochemistry (2005)

  2. No Access

    Article

    Liver-specific ZP domain-containing protein (LZP) as a new partner of Tamm-Horsfall protein harbors on renal tubules

    Liver-specific ZP domain-containing protein (LZP) was recently identified as a secreted protein that is specifically expressed in liver. However, the physiological effects of LZP are largely unknown. In this s...

    Hai-Lian Shen, Zhi-Gang Xu, Li-Yu Huang, Dong Liu… in Molecular and Cellular Biochemistry (2009)

  3. No Access

    Article

    Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein

    The Notch signaling pathway has been implicated in the development of several leukemia and lymphoma. In order to investigate the relationship between Notch signaling and acute myeloid leukemia (AML), in this s...

    Guo-Hui Li, Yu-Zhen Fan, **ao-Wei Liu… in Molecular and Cellular Biochemistry (2010)

  4. No Access

    Article

    PTP1B inhibitor improves both insulin resistance and lipid abnormalities in vivo and in vitro

    PTP1B is a negative regulator of insulin signaling pathway. This study investigated the effects of compound CCF06240, a PTP1B inhibitor, on insulin sensitivity and lipid metabolic abnormalities in vivo and in ...

    Yi-ming Ma, Rong-ya Tao, Qian Liu, Juan Li… in Molecular and Cellular Biochemistry (2011)

  5. No Access

    Article

    Activation of hypoxia-inducible factor-1 ameliorates postischemic renal injury via inducible nitric oxide synthase

    Hypoxia-inducible factor-1 (HIF-1) could ameliorate renal ischemia reperfusion injury (IRI), but the underlying mechanism remains elusive. In the current study, we aim to investigate the possible role of proly...

    **ao-Li Zhang, Zhen-Wen Yan, Wei-Wen Sheng… in Molecular and Cellular Biochemistry (2011)

  6. No Access

    Article

    Coordinated regulation of autophagy and apoptosis determines endothelial cell fate during Dengue virus type 2 infection

    Dengue is the most prevalent mosquito-borne viral disease in tropical regions. Severe cases may progress to Dengue hemorrhagic fever, suggesting vascular endothelial dysfunction in disease pathogenesis. In our...

    Junqi Huang, Ying Li, Yiming Qi, Yingke Zhang… in Molecular and Cellular Biochemistry (2014)

  7. No Access

    Article

    Bergapten promotes bone marrow stromal cell differentiation into osteoblasts in vitro and in vivo

    Many recent studies have suggested that bergapten (BP), a class of native compound with numerous biological activities such as anti-resorptive properties, may exert protective effects against postmenopausal bo...

    Ji-jie **ao, Wen-ji Zhao, **n-tao Zhang… in Molecular and Cellular Biochemistry (2015)

  8. No Access

    Article

    Vascular endothelial growth factor-C protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis

    VEGF-C is a newly identified proangiogenic protein playing an important role in vascular disease and angiogenesis. However, its role in myocardial ischemia/reperfusion (I/R) injury remains unknown. The objecti...

    Xu-guang Chen, Yan-xia Lv, Dan Zhao, Lei Zhang… in Molecular and Cellular Biochemistry (2016)

  9. No Access

    Article

    Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer

    The zinc-finger transcription factor Snail1 is inappropriately expressed in breast cancer and associated with poor prognosis. While interrogating human databases, we uncovered marked decreases in relapse-free ...

    Ting Ni, **ao-Yan Li, Na Lu, Teng An, Zhi-** Liu, Rong Fu… in Nature Cell Biology (2016)

  10. No Access

    Article

    Endothelial retinoblastoma protein reduces abdominal aortic aneurysm development via promoting DHFR/NO pathway-mediated vasoprotection

    Cardiovascular disease (CVD) is a major cause of global mortality. The proper functioning of the endothelial layer of arteries is crucial to cardiovascular health. Retinoblastoma protein (Rb), encoded by the Rb1 ...

    Yu Cao, Da **ong, Ruize Kong, Guolin Dai… in Molecular and Cellular Biochemistry (2019)

  11. No Access

    Article

    PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation

    PTENα and PTENβ are two longer translational variants of phosphatase and tensin homolog (PTEN) messenger RNA. Their expressional regulations and functions in carcinogenesis remain largely unknown. Here, we dem...

    Shao-Ming Shen, Cheng Zhang, Meng-Kai Ge, Shuang-Shu Dong, Li **a… in Nature Cell Biology (2019)

  12. No Access

    Article

    Manganese regulation of COPII condensation controls circulating lipid homeostasis

    Precise control of circulating lipids is instrumental in health and disease. Bulk lipids, carried by specialized lipoproteins, are secreted into the circulation, initially via the coat protein complex II (COPI...

    **ao Wang, Runze Huang, Yawei Wang, Wen**g Zhou, Yating Hu… in Nature Cell Biology (2023)

  13. No Access

    Article

    CircHAT1 regulates the proliferation and phenotype switch of vascular smooth muscle cells in lower extremity arteriosclerosis obliterans through targeting SFRS1

    This study aimed to decipher the mechanism of circular ribonucleic acids (circRNAs) in lower extremity arteriosclerosis obliterans (LEASO). First, bioinformatics analysis was performed for screening significan...

    **an-ying Huang, Fang-yong Fu, Kai Qian… in Molecular and Cellular Biochemistry (2024)