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Article
A global survey on the use of the international classification of diseases codes for metabolic dysfunction-associated fatty liver disease
With the implementation of the 11th edition of the International Classification of Diseases (ICD-11) and the publication of the metabolic dysfunction-associated fatty liver disease (MAFLD) nomenclature in 2020...
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Article
Open AccessTC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis
Tandem C2 domains, nuclear (TC2N) is a C2 domain-containing protein that belongs to the carboxyl-terminal type (C-type) tandem C2 protein family, and acts as an oncogenic driver in several cancers. Previously,...
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Article
Danhong Injection Up-regulates miR-125b in Endothelial Exosomes and Attenuates Apoptosis in Post-Infarction Myocardium
To investigate the involvement of endothelial cells (ECs)-derived exosomes in the anti-apoptotic effect of Danhong Injection (DHI) and the mechanism of DHI-induced exosomal protection against postinfarction my...
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Article
Measurement of the 232Th(n,f) cross section in the 1–200 MeV range at the CSNS Back-n
The 232Th(n,f) cross section is very important in basic nuclear physics and applications based on the Th/U fuel cycle. Using the time-of-flight method and a multi-cell fast-fission ionization chamber, a novel mea...
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Article
A quick online cross-sectional study of knowledge, attitude, practice, and information media toward the Omicron pandemic in China
The knowledge, attitudes, and practices (KAP) toward the COVID-19 and popular information media of the public is unclear in the late pandemic. The objective of this study was to evaluate the Chinese residents’...
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Article
Porous organic polymers: a progress report in China
Porous organic polymers (POPs) are porous materials composed of light elements such as C, H, N, and O. The benign characters, including large surface area, good physical and chemical stability, well-defined ch...
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Article
Arginine methylation of MTHFD1 by PRMT5 enhances anoikis resistance and cancer metastasis
Metastasis accounts for the major cause of cancer-related mortality. How disseminated tumor cells survive under suspension conditions and avoid anoikis is largely unknown. Here, using a metabolic enzyme-center...
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Article
Open AccessSt13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis
Early diagnosis and treatment of chronic pancreatitis (CP) are limited. In this study, St13, a co-chaperone protein, was investigated whether it constituted a novel regulatory target in CP. Meanwhile, we evalu...
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Article
Lingbao Huxin Pill Alleviates Apoptosis and Inflammation at Infarct Border Zone through SIRT1-Mediated FOXO1 and NF- κ B Pathways in Rat Model of Acute Myocardial Infarction
To investigate whether Lingbao Huxin Pill (LBHX) protects against acute myocardial infarction (AMI) at the infarct border zone (IBZ) of myocardial tissue by regulating apoptosis and inflammation through the si...
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Article
Open AccessDetecting visually significant cataract using retinal photograph-based deep learning
Age-related cataracts are the leading cause of visual impairment among older adults. Many significant cases remain undiagnosed or neglected in communities, due to limited availability or accessibility to catar...
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Article
Open AccessAstragalus mongholicus Bunge and Panax notoginseng formula (A&P) improves renal mesangial cell damage in diabetic nephropathy by inhibiting the inflammatory response of infiltrated macrophages
Diabetic nephropathy (DN) is one of the main causes of end-stage renal disease with scantly effective treatment. Numerous evidences indicated that macrophages play an important role in the occurrence and patho...
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Article
Quantum Speed Limit Time of a Two-Level Atom under Homodyne-Mediated Feedback and Classical Driving
We study the QSLT of the two-level system coupling to a single mode cavity which is driven by a laser field under the feedback control, and focus on the effect of the Rabi frequency and two types of the feedba...
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Article
Multi-factor influence of cross-sectional airflow distribution in roadway with rough roof
The wall surface roughness renders a significant impact on ventilation of roadways and cross-sectional wind speed distribution. Herein, the wall roughness (Ra) in the roadway has been defined theoretically. Moreo...
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Article
Current development of body-centered cubic high-entropy alloys for nuclear applications
High-entropy alloys greatly expand the alloy design range and offer new possibilities for improving material performance. Based on the worldwide research efforts in the last decade, the excellent mechanical pr...
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Article
Open AccesscircST6GALNAC6 suppresses bladder cancer metastasis by sponging miR-200a-3p to modulate the STMN1/EMT axis
Bladder cancer (BCa) is an aggressive malignancy because of its distant metastasis and high recurrence rate. Circular RNAs (circRNAs) exert critical regulatory functions in cancer progression. However, the exp...
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Article
Back-n white neutron source at CSNS and its applications
Back-streaming neutrons from the spallation target of the China Spallation Neutron Source (CSNS) that emit through the incoming proton channel were exploited to build a white neutron beam facility (the so-call...
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Article
Discovery of oscillations above 200 keV in a black hole X-ray binary with Insight-HXMT
Low-frequency quasiperiodic oscillations (LFQPOs) are commonly found in black hole X-ray binaries, and their origin is still under debate. The properties of LFQPOs at high energies (above 30 keV) are closely r...
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Article
Open AccessEMC6 regulates acinar apoptosis via APAF1 in acute and chronic pancreatitis
Treatment of acute pancreatitis (AP) and chronic pancreatitis (CP) remains problematic due to a lack of knowledge about disease-specific regulatory targets and mechanisms. The purpose of this study was to scre...
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Article
Radiation effect on ionic liquid [Hbet][Tf2N] for Nd2O3 separation from simulated spent nuclear fuels
Radiation-chemical stability of ionic liquid [Hbet][Tf2N] has been investigated under gamma irradiation for Nd2O3 separation from simulated spent nuclear fuels. It was found that Nd2O3 dissolution decreases with ...
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Article
Quantum Fisher Information of a Two-Qubit System in Non-Markovian Environment
Considering a two-qubit system interacting with a common bosonic reservoir, this paper investigates the quantum Fisher information dynamics in the Markovian and non-Markovian environments, and focuses on the e...
