9 Result(s)

Article

EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma

Platelet-derived growth subunit A (PDGFA) plays critical roles in development of glioblastoma (GBM) with substantial evidence from TCGA database analyses and in vivo mouse models. So far, only platelet-derived...

Qu-**g Gai, Zhen Fu, Jiang He, Min Mao… in Signal Transduction and Targeted Therapy (2022)

Article

Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...

Jun Liu, Dan-Dan Li, Wei Dong, Yu-Qi Liu… in Signal Transduction and Targeted Therapy (2021)

Article

Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Hefei (2014–2015): genetic characteristics of antimicrobial resistance

Antimicrobial resistance (AMR) and genetic determinants of resistance of N. gonorrhoeae isolates from Hefei, China, were characterized adding a breadth of information to the molecular epidemiology of gonococcal r...

Fa-**ng Jiang, Qian Lan, Wen-**g Le, **ao-Hong Su in BMC Infectious Diseases (2017)

Article

Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats

To investigate the effect of chronic nicotine treatment on vascular function and to identify the underlying mechanisms.

Tian-ying Xu, **ao-hong Lan, Yun-feng Guan, Sai-long Zhang… in Acta Pharmacologica Sinica (2015)

Article

Zuo ** Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway

Zuo-**-Wan (ZJW), a traditional Chinese medicine formula, has been identified to be effective against drug resistance in cancer. In the present study, we investigated the effect of ZJW on acquired oxaliplatin...

Hua Sui, Shu-Fang Pan, Yu Feng, Bao-Hui **… in BMC Complementary and Alternative Medicine (2014)

Article

Radiofrequency ablation following first-line transarterial chemoembolization for patients with unresectable hepatocellular carcinoma beyond the Milan criteria

Recent studies suggest that a combination of radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) may have theoretical advantages over TACE alone for treatment of hepatocellular carcinoma (...

Lan Zhang, **n Yin, Yu-hong Gan, Bo-heng Zhang, Ju-bo Zhang… in BMC Gastroenterology (2014)

Article

Effects of notoginosides on proliferation and upregulation of GR nuclear transcription factor in hematopoietic cells

To investigate the effects of panax notoginosides (PNS) on the proliferation of human hematopoietic stem/progenitor cells, and to explore the signaling pathway of the nuclear transcription factor of the glucoc...

Rui-lan Gao, **ao-hong Chen, **ao-jie Lin, Xu-dai Qian… in Acta Pharmacologica Sinica (2007)

Article

35th Annual Meeting of the European Association for the Study of Diabetes

A. Melander, J. Olsson, G. Lindberg, A. Salzman, T. Howard, P. Stang… in Diabetologia (1999)