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  1. Article

    Open Access

    Differential cytokine expression in gastric tissues highlights helicobacter pylori’s role in gastritis

    Helicobacter pylori (H. pylori), known for causing gastric inflammation, gastritis and gastric cancer, prompted our study to investigate the differential expression of cytokines in gastric tissues, which is cruci...

    **ng-Tang Yang, Pei-Qin Niu, **ao-Feng Li, Ming-Ming Sun, Wei Wei in Scientific Reports (2024)

  2. Article

    Open Access

    Topological minibands and interaction driven quantum anomalous Hall state in topological insulator based moiré heterostructures

    The presence of topological flat minibands in moiré materials provides an opportunity to explore the interplay between topology and correlation. In this work, we study moiré minibands in topological insulator ...

    Kaijie Yang, Zian Xu, Yanjie Feng, Frank Schindler, Yuanfeng Xu in Nature Communications (2024)

  3. Article

    Open Access

    A contact-electro-catalysis process for producing reactive oxygen species by ball milling of triboelectric materials

    Ball milling is a representative mechanochemical strategy that uses the mechanical agitation-induced effects, defects, or extreme conditions to activate substrates. Here, we demonstrate that ball grinding coul...

    Ziming Wang, Xuanli Dong, **ao-Fen Li, Yawei Feng, Shunning Li in Nature Communications (2024)

  4. Article

    Open Access

    Camrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single-arm, phase 2 trial

    Immunotherapy combined with antiangiogenic targeted therapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for refractory recurrent/metastatic nasopharyngeal carcinom...

    Li Yuan, Guo-Dong Jia, **ao-Fei Lv, Si-Yi **e, Shan-Shan Guo in Nature Communications (2023)

  5. Article

    Open Access

    The pre-surgical role of halo-traction in patients with cervical infection associated with refractory kyphosis: a retrospective study

    To minimize surgical complications and staged procedures halo-traction is often used during deformity corrections. But the use of halo-traction in the treatment of refractory cervical kyphosis secondary to inf...

    Daudi R. Manini, Hong-Qi Zhang, Qile Gao, Shao-Hua Liu, Wang Yu**ang in Scientific Reports (2023)

  6. Article

    Open Access

    Coherent dynamics of multi-spin V \({}_{{{{{{{{\rm{B}}}}}}}}}^{-}\) center in hexagonal boron nitride

    Hexagonal boron nitride (hBN) has recently been demonstrated to contain optically polarized and detected electron spins that can be utilized for implementing qubits and quantum sensors in nanolayered-devices. ...

    Wei Liu, Viktor Ivády, Zhi-Peng Li, Yuan-Ze Yang, Shang Yu in Nature Communications (2022)

  7. Article

    Open Access

    Genomic analyses of 10,376 individuals in the Westlake BioBank for Chinese (WBBC) pilot project

    We initiate the Westlake BioBank for Chinese (WBBC) pilot project with 4,535 whole-genome sequencing (WGS) individuals and 5,841 high-density genoty** individuals, and identify 81.5 million SNPs and INDELs, ...

    Pei-Kuan Cong, Wei-Yang Bai, **-Chen Li, Meng-Yuan Yang in Nature Communications (2022)

  8. Article

    Open Access

    The lipid components of high-density lipoproteins (HDL) are essential for the binding and transportation of antimicrobial peptides in human serum

    Antimicrobial peptides (AMPs) have been developed for the treatment of bacterial infections, but their applications are limited to topical infections since they are sequestered and inhibited in serum. Here we ...

    Wen-Hung Tang, Shi-Han Wang, Chiu-Feng Wang, Yun Mou, Min-Guan Lin in Scientific Reports (2022)

  9. Article

    Open Access

    Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma

    Tumour lineage plasticity is an emerging hallmark of aggressive tumours. Tumour cells usually hijack developmental signalling pathways to gain cellular plasticity and evade therapeutic targeting. In the presen...

    Wei Cheng, Hao-Long Li, Shao-Yan **, **ao-Feng Zhang, Yun Zhu in Nature Communications (2021)

  10. Article

    Open Access

    Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons

    Long noncoding RNAs (lncRNAs) are known to regulate DNA damage response (DDR) and genome stability in proliferative cells. However, it remains unknown whether lncRNAs are involved in these vital biological pro...

    Min-Min Lou, **ao-Qiang Tang, Guang-Ming Wang, Jia He, Fang Luo in Nature Communications (2021)

  11. Article

    Open Access

    FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer

    Most patients with triple negative breast cancer (TNBC) do not respond to anti-PD1/PDL1 immunotherapy, indicating the necessity to explore immune checkpoint targets. B7H3 is a highly glycosylated protein. Howe...

    Yun Huang, Hai-Liang Zhang, Zhi-Ling Li, Tian Du, Yu-Hong Chen in Nature Communications (2021)

  12. Article

    Open Access

    1/f-noise-free optical sensing with an integrated heterodyne interferometer

    Optical evanescent sensors can non-invasively detect unlabeled nanoscale objects in real time with unprecedented sensitivity, enabling a variety of advances in fundamental physics and biological applications. ...

    Ming **, Shui-**g Tang, **-Hui Chen, **ao-Chong Yu, Haowen Shu in Nature Communications (2021)

  13. Article

    Open Access

    Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation

    Most triple-negative breast cancer (TNBC) patients fail to respond to T cell-mediated immunotherapies. Unfortunately, the molecular determinants are still poorly understood. Breast cancer is the disease geneti...

    Zhi-Ling Li, Hai-Liang Zhang, Yun Huang, Jun-Hao Huang, Peng Sun in Nature Communications (2020)

  14. Article

    Open Access

    Investigation of Cavity Enhanced XEOL of a Single ZnO Microrod by Using Multifunctional Hard X-ray Nanoprobe

    The multifunctional hard X-ray nanoprobe at Taiwan Photon Source (TPS) exhibits the excellent ability to simultaneously characterize the X-ray absorption, X-ray excited optical luminescence (XEOL) as well as t...

    Bi-Hsuan Lin, **ao-Yun Li, Dai-Jie Lin, Bo-Lun Jian, Hsu-Cheng Hsu in Scientific Reports (2019)

  15. Article

    Open Access

    IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population

    Interleukin-13 (IL-13) has important functions in atherosclerosis, but its role in coronary artery disease (CAD) is unclear. Here, we studied the genetic role of IL-13 in CAD in a Chinese Han population using ...

    Ling-Feng Zha, Shao-Fang Nie, Qian-Wen Chen, Yu-Hua Liao in Scientific Reports (2018)

  16. Article

    Open Access

    Effectiveness of Traditional Chinese Medicineas as an Adjunct Therapy for Refractory Schizophrenia: A Systematic Review and Meta Analysis

    Although recent studies focused on traditional Chinese medicine (TCM) for the treatment of refractory schizophrenia have reported that it may be beneficial, there is still lack of convincing evidence and criti...

    Yan-Yan Wei, Wan-Fu Lin, Tian-Hong Zhang, Yun-**ang Tang, Ji-Jun Wang in Scientific Reports (2018)

  17. Article

    Open Access

    Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens

    This study investigated global gene and protein expression in the small yellow follicle (SYF; 6–8 mm in diameter) tissues of chickens in response to acute heat stress. Twelve 30-week-old layer-type hens were d...

    Chuen-Yu Cheng, Wei-Lin Tu, Chao-Jung Chen, Hong-Lin Chan in Scientific Reports (2018)

  18. Article

    Open Access

    CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation

    Autophagy is a degradative pathway that delivers cellular components to the lysosome for degradation. The role of autophagy in cell differentiation is poorly understood. Here we show that CaMKII can directly p...

    Xuan Li, **ao-Qi Wu, Rong Deng, Dan-Dan Li, Jun Tang, Wen-Dan Chen in Nature Communications (2017)

  19. Article

    Open Access

    Bacterial diversity among four healthcare-associated institutes in Taiwan

    Indoor microbial communities have important implications for human health, especially in health-care institutes (HCIs). The factors that determine the diversity and composition of microbiomes in a built enviro...

    Chang-Hua Chen, Yaw-Ling Lin, Kuan-Hsueh Chen, Wen-Pei Chen in Scientific Reports (2017)

  20. Article

    Open Access

    Antidepressant effect of taurine in chronic unpredictable mild stress-induced depressive rats

    Depression, a psychiatric and dysthymic disorder, severely affects the learning, work and life quality. The main pathogenesis of depression is associated with central nervous system (CNS) dysfunction. Taurine ...

    Gao-Feng Wu, Shuang Ren, Ri-Yi Tang, Chang Xu, Jia-Qi Zhou in Scientific Reports (2017)

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