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Article
Open AccessTwo Decades of Publications in Journals Dedicated to Autoimmunity: A Bibliometric Analysis of the Autoimmunity Field from 2004 to 2023
To carry out an in-depth analysis of the scientific research on autoimmunity, we performed the first bibliometric analysis focusing on publications in journals dedicated to autoimmunity (JDTA) indexed by scien...
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Article
Vascular smooth muscle-specific LRRC8A knockout ameliorates angiotensin II-induced cerebrovascular remodeling by inhibiting the WNK1/FOXO3a/MMP signaling pathway
Hypertensive cerebrovascular remodeling involves the enlargement of vascular smooth muscle cells (VSMCs), which activates volume-regulated Cl− channels (VRCCs). The leucine-rich repeat-containing family 8 A (LRRC...
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Article
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E2 in the lateral parabrachial nucleus of male rats
It has been shown that prostaglandin (PG) E2 synthesized in the lateral parabrachial nucleus (LPBN) is involved in lipopolysaccharide-induced fever. But the neural mechanisms of how intra-LPBN PGE2 induces fever ...
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Article
Open AccessDownregulation of GPX8 in hepatocellular carcinoma: impact on tumor stemness and migration
GPX8, which is found in the endoplasmic reticulum lumen, is a member of the Glutathione Peroxidases (GPXs) family. Its role in hepatocellular carcinoma (HCC) is unknown.
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Article
A hypoxic pyrolysis process to turn petrochemical sludge into magnetic biochar for cadmium-polluted soil remediation
Biochar has been considered as a promising material for soil remediation, particularly for its ability to reduce the bioavailability of cadmium (Cd) in soil through sorption. However, long-term remediation may...
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Article
Open AccessDifferential cytokine expression in gastric tissues highlights helicobacter pylori’s role in gastritis
Helicobacter pylori (H. pylori), known for causing gastric inflammation, gastritis and gastric cancer, prompted our study to investigate the differential expression of cytokines in gastric tissues, which is cruci...
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Article
Open AccessTopological minibands and interaction driven quantum anomalous Hall state in topological insulator based moiré heterostructures
The presence of topological flat minibands in moiré materials provides an opportunity to explore the interplay between topology and correlation. In this work, we study moiré minibands in topological insulator ...
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Article
Open AccessChanges in disease burden and global inequalities in bladder, kidney and prostate cancers from 1990 to 2019: a comparative analysis based on the global burden of disease study 2019
Bladder, kidney and prostate cancers make significant contributors to cancer burdens. Exploring their cross-country inequalities may inform equitable strategies to meet the 17 sustainable development goals bef...
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Article
Open AccessA contact-electro-catalysis process for producing reactive oxygen species by ball milling of triboelectric materials
Ball milling is a representative mechanochemical strategy that uses the mechanical agitation-induced effects, defects, or extreme conditions to activate substrates. Here, we demonstrate that ball grinding coul...
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Chapter and Conference Paper
A New Technology for Enhanced Oil Recovery in Tight Oil Reservoirs: CO2/Low Interfacial Tension Viscoelastic Fluid Co-flooding
Tight reservoirs have poor physical properties, strong heterogeneity and low water flooding natural productivity. CO2 flooding can effectively improve oil recovery and reduce carbon emissions, but CO2 flooding is...
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Chapter and Conference Paper
A New Method of Noise Spectrum Technology to Identify Reservoir Flow Profile
Traditional production logging (PLT) is limited by the casing or completion strings and can’t represent the flow behind the casing or flow in the reservoir. Noise spectrum logging technology (NTO) measures the...
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Article
Efficacy and Safety of Different Doses of Rivaroxaban and Risk Factors for Bleeding in Elderly Patients with Venous Thromboembolism: A Real-World, Multicenter, Observational, Cohort Study
Venous thromboembolism (VTE) consists of deep vein thrombosis (DVT) and pulmonary embolism (PE). Rivaroxaban is a direct oral anticoagulant (DOAC) inhibiting activated coagulation factor X (FXa), and exerts se...
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Article
Open AccessLongitudinal changes in magnetic resonance imaging biomarkers of the gluteal muscle groups and functional ability in Duchenne muscular dystrophy: a 12-month cohort study
Quantitative magnetic resonance imaging (MRI) is considered an objective biomarker of Duchenne muscular dystrophy (DMD), but the longitudinal progression of MRI biomarkers in gluteal muscle groups and their pr...
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Article
Open AccessRadiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study
Post-radiation nasopharyngeal necrosis (PRNN) is a severe adverse event following re-radiotherapy for patients with locally recurrent nasopharyngeal carcinoma (LRNPC) and associated with decreased survival. Bi...
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Article
Open AccessSingle-cell and spatial architecture of primary liver cancer
Primary liver cancer (PLC) poses a leading threat to human health, and its treatment options are limited. Meanwhile, the investigation of homogeneity and heterogeneity among PLCs remains challenging. Here, usi...
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Article
Head and neck MRI-based T stage and [18F]FDG PET/CT-based N/M stage improved prognostic stratification in primary nasopharyngeal carcinoma
To evaluate whether MRI-based T stage (TMRI), [18F]FDG PET/CT-based N (NPET/CT), and M stage (MPET/CT) are superior in NPC patients’ prognostic stratification based on long-term survival evidences, and whether TN...
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Article
The role and mechanisms of microvascular damage in the ischemic myocardium
Following myocardial ischemic injury, the most effective clinical intervention is timely restoration of blood perfusion to ischemic but viable myocardium to reduce irreversible myocardial necrosis, limit infar...
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Article
Open AccessTrim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling
Despite the diverse roles of tripartite motif (Trim)-containing proteins in the regulation of autophagy, the innate immune response, and cell differentiation, their roles in skeletal diseases are largely unkno...
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Article
Open AccessThe mechanism of ferroptosis and its related diseases
Ferroptosis, a regulated form of cellular death characterized by the iron-mediated accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of cellular metabolism, oxidative s...
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Article
Open AccessA universal programmable Gaussian boson sampler for drug discovery
Gaussian boson sampling (GBS) has the potential to solve complex graph problems, such as clique finding, which is relevant to drug discovery tasks. However, realizing the full benefits of quantum enhancements ...
