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Article
Open AccessEfficacy and acceptability of different probiotic products plus laxatives for pediatric functional constipation: a network meta-analysis of randomized controlled trials
The prevalence of pediatric constipation ranges from 0.7 to 29.6% across different countries. Functional constipation accounts for 95% of pediatric constipation, and the efficacy of pharmacotherapy is limited,...
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Article
Open AccessDeciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis
Fas-associated protein with death domain (FADD), procaspase-8, and cellular FLICE-inhibitory proteins (cFLIP) assemble through death-effector domains (DEDs), directing death receptor signaling towards cell sur...
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Article
Open AccessMicrobial communities modulate chemical weathering and carbon dioxide cycling in an active orogen in Taiwan
Chemical weathering modulates carbon transfer between the crust, hydrosphere, and atmosphere. The extent to which microbial processes are involved in mineral dissolution remains elusive. Here, we performed geo...
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Article
Prophylaxis for paediatric emergence delirium in desflurane-based anaesthesia: a network meta-analysis
The prevalence of postoperative emergence delirium in paediatric patients (pedED) following desflurane anaesthesia is considerably high at 50–80%. Although several pharmacological prophylactic strategies have ...
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Article
Effect of Regional Brain Activity Following Repeat Transcranial Magnetic Stimulation in SCA3: A Secondary Analysis of a Randomized Clinical Trial
Repetitive transcranial magnetic stimulation (rTMS), a noninvasive neuroregulatory technique used to treat neurodegenerative diseases, holds promise for spinocerebellar ataxia type 3 (SCA3) treatment, although...
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Article
Stark splitting of intense red emission for Er3+ in Oh symmetry sites realizing optical temperature sensing in biological applications
Optical temperature sensing based on the fluorescence intensity ratio (FIR) of red emission for lanthanide ions holds significant relevance in non-contact temperature measurement for biological application. In...
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Article
Comparative efficacy of hypnotics in young and middle-aged adults with insomnia: a systematic review and network meta-analysis
Insomnia is highly prevalent in modern society. However, the hierarchical selection of hypnotics in young and middle-aged adults with insomnia remains unclear. We aimed to compare the efficacy and daytime drow...
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Article
Association of bisphosphonates with diabetes risk and glycemic control: a meta-analysis
Previous evidence suggests that bisphosphonates may improve glycemic control. The present meta-analysis, comprising seven studies with 1,233,844 participants, demonstrated that bisphosphonate use was significa...
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Article
Open AccessThe beneficial effect on cognition of noninvasive brain stimulation intervention in patients with dementia: a network meta-analysis of randomized controlled trials
Dementia [i.e., Alzheimer disease (AD)], the most common neurodegenerative disease, causes profound negative impacts on executive function and quality of life. Available pharmacological treatments often fail t...
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Vascular Disorders of the Small Intestines
Vascular lesions constituted a major proportion (21% to 57%) of all small intestinal obscure gastrointestinal bleeding cases. It is one important cause of obscure gastrointestinal bleeding and diagnosis is cha...
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Article
A Macroporous Cryogel with Enhanced Mechanical Properties for Osteochondral Regeneration In vivo
The dense networks of conventional hydrogel hinder the efficient cell penetration and thus tissue regeneration. In this study, a macroporous cryogel with excellent mechanical properties was designed and fabric...
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Article
Open AccessThe explorations of the awareness, contemplation, self-Efficacy, and readiness of advance care planning, and its predictors in Taiwanese patients while receiving hemodialysis treatment
End-stage renal disease (ESRD) is a major chronic illness worldwide, and Taiwan reports one of the highest incidence rates of ESRD with 529 cases per million population (pmp). A number of patients with ESRD pa...
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Article
Synthesis and luminescence of ultrasmall CsPbBr3 nanocrystals and CsPbBr3/Cs4PbBr6 composites by one-pot method
All-inorganic perovskites CsPbX3 (X = Cl, Br, I) have attracted worldwide interest due to their excellent luminescent performances. Meanwhile, Cs4PbBr6 have been studied because they can enhance the luminescent e...
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Article
Open AccessEffectiveness and acceptability of noninvasive brain and nerve stimulation techniques for migraine prophylaxis: a network meta-analysis of randomized controlled trials
Current pharmacologic prophylactic strategies for migraine have exhibited limited efficacy, with response rates as low as 40%–50%. In addition to the limited efficacy, the acceptability of those pharmacologic ...
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Article
Efficacy and acceptability of noninvasive brain stimulation interventions for weight reduction in obesity: a pilot network meta-analysis
Obesity has recently been recognized as a neurocognitive disorder involving circuits associated with the reward system and the dorsolateral prefrontal cortex (DLPFC). Noninvasive brain stimulation (NIBS) has b...
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Article
Chemical Constituents of the Endophytic Fungus Penicillium macrosclerotiorum from Sophora tonkinensis
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Article
Open AccessDevelopment and validation of the cancer symptoms discrimination scale: a cross-sectional survey of students in Yunnan, China
This study aimed to devise a Cancer symptoms Discrimination Scale (CSDS) suitable for China based on a cross-sectional survey.
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Article
Diffusion tensor imaging predicting neurological repair of spinal cord injury with transplanting collagen/chitosan scaffold binding bFGF
Prognosis and treatment evaluation of spinal cord injury (SCI) are still in the long-term research stage. Prognostic factors for SCI treatment need effective biomarker to assess therapeutic effect. Quantitativ...
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Article
Clinical significance of quantitative assessment of right ventricular glucose metabolism in patients with heart failure with reduced ejection fraction
Dynamic 18F-fluorodeoxyglucose (FDG) PET can be used to quantitatively assess the rate of myocardial glucose uptake (MRGlu). The aim of this study was to evaluate the clinical significance and prognostic value of...
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Article
Open AccessElement Effects on High-Entropy Alloy Vacancy and Heterogeneous Lattice Distortion Subjected to Quasi-equilibrium Heating
We applied Simmons–Balluffi methods, positron measurements, and neutron diffraction to estimate the vacancy of CoCrFeNi and CoCrFeMnNi high-entropy alloys (HEAs) using Cu as a benchmark. The corresponding form...
