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    Article

    Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages

    Ulcerative colitis (UC) is associated with changed dietary habits and mainly linked with the gut microbiota dysbiosis, necroptosis of epithelial cells, and mucosal ulcerations. Liver dysfunction and abnormal l...

    Mo-ting Liu, Yao Zhang, Cai-gui **ang, Tao Yang in Acta Pharmacologica Sinica (2024)

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    Article

    Novel STAT3 oligonucleotide compounds suppress tumor growth and overcome the acquired resistance to sorafenib in hepatocellular carcinoma

    Signal transducer and activator of transcription 3 (STAT3) plays an important role in the occurrence and progression of tumors, leading to resistance and poor prognosis. Activation of STAT3 signaling is freque...

    Qi-yi Zhang, Wen Ding, Jian-shan Mo, Shu-min Ou-yang in Acta Pharmacologica Sinica (2024)

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    Open Access

    Metabolism-regulating non-coding RNAs in breast cancer: roles, mechanisms and clinical applications

    Breast cancer is one of the most common malignancies that pose a serious threat to women's health. Reprogramming of energy metabolism is a major feature of the malignant transformation of breast cancer. Compar...

    Shiliang Xu, Lingxia Wang, Yuexin Zhao, Tong Mo, Bo Wang in Journal of Biomedical Science (2024)

  4. Article

    Open Access

    GMPPB-congenital disorders of glycosylation associate with decreased enzymatic activity of GMPPB

    The congenital disorders of glycosylation (CDG) are a family of metabolic diseases in which glycosylation of proteins or lipids is deficient. GDP-mannose pyrophosphorylase B (GMPPB) mutations lead to CDG, char...

    Zhe Liu, Yan Wang, Fan Yang, Qin Yang, **anming Mo, Ezra Burstein in Molecular Biomedicine (2021)

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    Article

    Screen p53 mutations in hepatocellular carcinoma by FASAY: A novel splicing mutation

    To establish a routine procedure for the detection of p53 mutations in hepatocellular carcinoma (HCC) surgical resections using the FASAY (functional analysis of separated alleles of p53 on yeast) procedure.

    **ao-mo Wu, **g-geng Fu, Wang-zhong Ge in Journal of Zhejiang University SCIENCE B (2007)