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Article
Viral-mediated gene therapy in pediatric neurological disorders
Due to the broad application of next-generation sequencing, the molecular diagnosis of genetic disorders in pediatric neurology is no longer an unachievable goal. However, treatments for neurological genetic d...
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Article
A 3D-printed analytical device seamlessly integrating sample treatment for electrochemical detection of IAA in Marchantia polymorpha
Because of the pivotal point of Marchantia polymorpha (M. polymorpha) in plant evolution, its auxin (mainly indole-3-acetic acid, IAA) levels could provide useful evidence for the study of the evolution of IAA. H...
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Article
Open AccessMass testing and characterization of 20-inch PMTs for JUNO
Main goal of the JUNO experiment is to determine the neutrino mass ordering using a 20 kt liquid-scintillator detector. Its key feature is an excellent energy resolution of at least 3% at 1 MeV, for which its ...
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Article
Open AccessA saturated map of common genetic variants associated with human height
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sa...
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Article
Open AccessSt13 protects against disordered acinar cell arachidonic acid pathway in chronic pancreatitis
Early diagnosis and treatment of chronic pancreatitis (CP) are limited. In this study, St13, a co-chaperone protein, was investigated whether it constituted a novel regulatory target in CP. Meanwhile, we evalu...
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Open AccessThe design and sensitivity of JUNO’s scintillator radiopurity pre-detector OSIRIS
The OSIRIS detector is a subsystem of the liquid scintillator filling chain of the JUNO reactor neutrino experiment. Its purpose is to validate the radiopurity of the scintillator to assure that all components...
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Article
Open AccessHorseshoe kidney with PLA2R-positive membranous nephropathy
Horseshoe kidney (HSK) is a common congenital defect of the urinary system. The most common complications are urinary tract infection, urinary stones, and hydronephrosis. HSK can be combined with glomerular di...
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Article
Sensing mechanism of Ag/α-MoO3 nanobelts for H2S gas sensor
Sensing mechanism is still a big problem in the field of gas sensor. In-depth study of the sensing mechanism can provide better ideas for the design of sensing materials, and it is also more conducive to the i...
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Open AccessCalibration strategy of the JUNO experiment
We present the calibration strategy for the 20 kton liquid scintillator central detector of the Jiangmen Underground Neutrino Observatory (JUNO). By utilizing a comprehensive multiple-source and multiple-posit...
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Article
Discovery of oscillations above 200 keV in a black hole X-ray binary with Insight-HXMT
Low-frequency quasiperiodic oscillations (LFQPOs) are commonly found in black hole X-ray binaries, and their origin is still under debate. The properties of LFQPOs at high energies (above 30 keV) are closely r...
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Article
Study on magnesium slag desulfurizer modified by additives in quenching hydration
The desulfurization performance of magnesium slag has been improved by the modified method of quenching hydration, but it still cannot meet the industrial requirements. Based on the research of additives for c...
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Article
Open AccessChinese expert consensus on echelons treatment of thoracic injury in modern warfare
The emergency treatment of thoracic injuries varies of general conditions and modern warfare. However, there are no unified battlefield treatment guidelines for thoracic injuries in the Chinese People’s Libera...
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Study on desulfurization performances of magnesium slag with different hydration modification
Modified magnesium slag could be used as a kind of practical desulfurizer. Four modification methods were studied in this paper, which were magnesium slag hydration, magnesium slag/fly ash hydration, magnesium...
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Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Article
Open AccessGeneration and characterization of a new mammalian cell line continuously expressing virus-like particles of Japanese encephalitis virus for a subunit vaccine candidate
Japanese encephalitis virus (JEV) is the most important cause of epidemic encephalitis in most Asian regions. There is no specific treatment available for Japanese encephalitis, and vaccination is the only eff...
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Article
Inhibition of Retinal Ganglion Cell Axonal Outgrowth Through the Amino-Nogo-A Signaling Pathway
Nogo-A is a myelin-derived inhibitor playing a pivotal role in the prevention of axonal regeneration. A functional domain of Nogo-A, Amino-Nogo, exerts an inhibitory effect on axonal regeneration, although the...
