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Article
2023: Weather and Climate Extremes Hitting the Globe with Emerging Features
Globally, 2023 was the warmest observed year on record since at least 1850 and, according to proxy evidence, possibly of the past 100 000 years. As in recent years, the record warmth has again been accompanied...
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Article
Fabrication of a novel bone adhesive (crosslinked phytic acid-gelatin coordinated with magnesium phosphate and calcined dolomite, and montmorillonite) for enhancing adhesion strength and biocompatibility
Bone adhesives are known as a promising fracture treatment material because they can quickly heal broken bones. However, the existing bone adhesives have the disadvantages of weak binding ability to bone tissu...
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Article
Acoustic emission characteristics in tensile-shear failure of non-persistent jointed rocks with different undulation angles
Tensile-shear failure commonly occurs during the construction of deep in-situ tunnels. In this paper, direct tensile-shear tests were conducted on rock-like specimens containing regular serrated joints using a...
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Article
Right ventricular dyssynchrony for the prediction of prognosis in patients with systemic lupus erythematosus-aaociated pulmonary arterial hypertension: a study with two-dimensional speckle tracking
Pulmonary arterial hypertension (PAH) is a common complication of systemic lupus erythematosus (SLE), and PAH can cause right ventricle (RV) remodel and dyssynchrony. The aim of this study was to explore the v...
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Article
Open AccessNasal vaccination of triple-RBD scaffold protein with flagellin elicits long-term protection against SARS-CoV-2 variants including JN.1
Develo** a mucosal vaccine against SARS-CoV-2 is critical for combatting the epidemic. Here, we investigated long-term immune responses and protection against SARS-CoV-2 for the intranasal vaccination of a t...
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Article
Application of Natural Medicinal Plants Active Ingredients in Oral Squamous Cell Carcinoma
Oral squamous cell carcinoma (OSCC) is the most common malignant cancer of the head and neck, with high morbidity and mortality, ranking as the sixth most common cancer in the world. The treatment of OSCC is m...
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Article
Burning Numbers of Barbells
Motivated by a discrete-time process intended to measure the speed of the spread of contagion in a graph, the burning number b(G) of a graph G, is defined as the smallest integer k for which there are vertices x1
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Article
Simple and field-adapted species identification of biological specimens combining multiplex multienzyme isothermal rapid amplification, lateral flow dipsticks, and universal primers for initial rapid screening without standard PCR laboratory
Species identification of biological specimens can provide the valuable clues and accelerate the speed of prosecution material processing for forensic investigation, especially when the case scene is inaccessi...
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Article
Open AccessMitochondrial and metabolic dysfunction of peripheral immune cells in multiple sclerosis
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by the infiltration of inflammatory cells and demyelination of nerves. Mitochondrial dysfunction has been implicated in the pathogenesis o...
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Article
Open AccessResearch on the development methodology for clinical practice guidelines for organic integration of traditional Chinese and Western medicine
Integrated traditional Chinese medicine (TCM) and Western medicine (WM) is a new medical science grounded in the knowledge bases of both TCM and WM, which then forms a unique modern medical system in China. In...
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Article
Review on modification routes for SnOx-based anodes for Li storage: morphological structure tuning and phase structure design
Fascinating with high specific capacity and moderate lithiation potential, SnOx-based materials have been intensively investigated as one of the most promising anodes for lithium-ion batteries. However, due to po...
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Article
Open Accessφ-fixed point results for nonlinear contractions with an application
In this paper, using the notion of w-distance in metric spaces, we introduce two types of nonlinear contractions, ( ...
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Article
Anticancer Activity of Diosgenin and Its Molecular Mechanism
Diosgenin, a steroidal sapogenin, obtained from Trigonella foenum-graecum, Dioscorea, and Rhizoma polgonati, has shown high potential and interest in the treatment of various cancers such as oral squamous cell ca...
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Article
Open AccessTransarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001)
There is considerable potential for integrating transarterial chemoembolization (TACE), programmed death-(ligand)1 (PD-[L]1) inhibitors, and molecular targeted treatments (MTT) in hepatocellular carcinoma (HCC...
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Article
Open AccessClinical characteristics and risk factors of ovarian reserve decreases in women with Crohn’s disease: a case-control study
Crohn’s disease (CD), often occurring in women of child-bearing age, can decline the fertility rate. However, whether it reduces ovarian reserve has been rarely reported. This study aimed to evaluate the ovari...
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Article
EPSTI1 promotes monocyte adhesion to endothelial cells in vitro via upregulating VCAM-1 and ICAM-1 expression
Atherosclerosis is a chronic inflammatory disease of arterial wall, and circulating monocyte adhesion to endothelial cells is a crucial step in the pathogenesis of atherosclerosis. Epithelial-stromal interacti...
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Article
Polyvinylpyrrolidone-assisted aqueous synthesis of monodisperse CH3NH3PbBr3 perovskite nanocrystals
Metal halide perovskites are difficult to be prepared entirely in water due to their ionic nature. Aqueous synthesis routes of methylammonium lead bromide (CH3NH3PbBr3) perovskite were reported previously, but th...
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Article
Open AccessHeart-targeting exosomes from human cardiosphere-derived cells improve the therapeutic effect on cardiac hypertrophy
Exosomes of human cardiosphere-derived cells (CDCs) are very promising for treating cardiovascular disorders. However, the current challenge is inconvenient delivery methods of exosomes for clinical applicatio...
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Article
Ion conduction path in composite solid electrolytes for lithium metal batteries: from polymer rich to ceramic rich
Solid-state electrolytes (SSEs) can address the safety issue of organic electrolyte in rechargeable lithium batteries. Unfortunately, neither polymer nor ceramic SSEs used alone can meet the demand although gr...
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Article
Roles of nanoscale precipitates and metastable austenite in determining strength and toughness of high-strength Nb-bearing steel
The effects of tempering temperature on the microstructure and mechanical properties of high-strength structural steel containing niobium were investigated to examine the roles of nanoscale precipitates and me...
