105 Result(s)
within
**ao-Bo **
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessMolecular ferroelectric with low-magnetic-field magnetoelectricity at room temperature
Magnetoelectric materials, which encompass coupled magnetic and electric polarizabilities within a single phase, hold great promises for magnetic controlled electronic components or electric-field controlled s...
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Open AccessThe Shigella kinase effector OspG modulates host ubiquitin signaling to escape septin-cage entrapment
Shigella flexneri is a Gram-negative bacterium causing severe bloody dysentery. Its pathogenesis is largely dictated by a plasmid-encoded type III secretion system (T3SS) and its associated effectors. Among these...
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Creation of memory–memory entanglement in a metropolitan quantum network
Towards realizing the future quantum internet1,2, a pivotal milestone entails the transition from two-node proof-of-principle experiments conducted in laboratories to comprehensive multi-node set-ups on large sca...
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Open AccessThe rise of baobab trees in Madagascar
The baobab trees (genus Adansonia) have attracted tremendous attention because of their striking shape and distinctive relationships with fauna1. These spectacular trees have also influenced human culture, inspir...
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Open AccessMolecular mechanisms underlying the BIRC6-mediated regulation of apoptosis and autophagy
Procaspase 9 is the initiator caspase for apoptosis, but how its levels and activities are maintained remains unclear. The gigantic Inhibitor-of-Apoptosis Protein BIRC6/BRUCE/Apollon inhibits both apoptosis an...
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Open AccessExperimental study on failure characteristics and rheological properties of pillar-like rock samples with different shapes
The stability of coal pillar is extremely important to the control of rock strata movement and surface subsidence. It is of great significance for mining design to analyze the stability and failure characteris...
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Open AccessCharge-4e superconductivity and chiral metal in 45°-twisted bilayer cuprates and related bilayers
The material realization of charge-4e/6e superconductivity (SC) is a big challenge. Here, we propose to realize charge-4e SC in maximally-twisted homobilayers, such as 45∘-twisted bilayer cuprates and 30∘-twisted...
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Open AccessIndocyanine green fluorescence imaging-guided versus conventional laparoscopic lymphadenectomy for gastric cancer: long-term outcomes of a phase 3 randomised clinical trial
Indocyanine green (ICG) fluorescence imaging-guided lymphadenectomy has been demonstrated to be effective in increasing the number of lymph nodes (LNs) retrieved in laparoscopic gastrectomy for gastric cancer ...
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Open AccessAccurate prediction by AlphaFold2 for ligand binding in a reductive dehalogenase and implications for PFAS (per- and polyfluoroalkyl substance) biodegradation
Despite the success of AlphaFold2 (AF2), it is unclear how AF2 models accommodate for ligand binding. Here, we start with a protein sequence from Acidimicrobiaceae TMED77 (T7RdhA) with potential for catalyzing th...
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Open Accessscm6A-seq reveals single-cell landscapes of the dynamic m6A during oocyte maturation and early embryonic development
N6-methyladenosine (m6A) has been demonstrated to regulate RNA metabolism and various biological processes, including gametogenesis and embryogenesis. However, the landscape and function of m6A at single cell res...
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Open AccessExpanding agroforestry can increase nitrate retention and mitigate the global impact of a leaky nitrogen cycle in croplands
The internal soil nitrogen (N) cycle supplies N to plants and microorganisms but may induce N pollution in the environment. Understanding the variability of gross N cycling rates resulting from the global spat...
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Open AccessExperimental generation of arbitrary abruptly autofusing Circular Airy Gaussian vortex vector beams
Complex vector modes represent a general state of light nonseparable in their spatial and polarization degrees of freedom, which have inspired a wide variety of novel applications and phenomena, such as their ...
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Open AccessAlphaFold2 models indicate that protein sequence determines both structure and dynamics
AlphaFold 2 (AF2) has placed Molecular Biology in a new era where we can visualize, analyze and interpret the structures and functions of all proteins solely from their primary sequences. We performed AF2 stru...
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Open AccessWAKE-mediated modulation of cVA perception via a hierarchical neuro-endocrine axis in Drosophila male-male courtship behaviour
The nervous and endocrine systems coordinate with each other to closely influence physiological and behavioural responses in animals. Here we show that WAKE (encoded by wide awake, also known as wake) modulates m...
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Open AccessDirect copolymerization of ethylene with protic comonomers enabled by multinuclear Ni catalysts
Ethylene/polar monomer coordination copolymerization offers an attractive way of making functionalized polyolefins. However, ethylene copolymerization with industrially relevant short chain length alkenoic aci...
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Open AccessPrevalence and related factors of dyslipidemia among urban adults aged 35 to 79 years in Southwestern China
This study aimed to investigate the prevalence of dyslipidemia and its related factors among urban adults aged 35 to 79 years in Southwestern China. From September 2013 to March 2014, a multi-stage sampling wa...
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Open AccessEvading strength-corrosion tradeoff in Mg alloys via dense ultrafine twins
Conventional ultrafine-grains can generate high strength in Mg alloys, but significant tradeoff of corrosion resistance due to inclusion of a large number of non-equilibrium grain boundaries. Herein, an ultraf...
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Open AccessAn integrated machine learning framework for a discriminative analysis of schizophrenia using multi-biological data
Finding effective and objective biomarkers to inform the diagnosis of schizophrenia is of great importance yet remains challenging. Relatively little work has been conducted on multi-biological data for the di...
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Open AccessTranscript levels of spindle and kinetochore-associated complex 1/3 as prognostic biomarkers correlated with immune infiltrates in hepatocellular carcinoma
The spindle and kinetochore-associated protein complex (Ska) is an essential component in chromosome segregation. It comprises three proteins (Ska1, Ska2, and Ska3) with theorized roles in chromosomal instabil...
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Open AccessProtein interaction potential landscapes for yeast replicative aging
We proposed a novel interaction potential landscape approach to map the systems-level profile changes of gene networks during replicative aging in Saccharomyces cerevisiae. This approach enabled us to apply quasi...
