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Article
Open AccessAn extended interaction site determines binding between AP180 and AP2 in clathrin mediated endocytosis
The early phases of clathrin mediated endocytosis are organized through a highly complex interaction network mediated by clathrin associated sorting proteins (CLASPs) that comprise long intrinsically disordere...
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Article
Untypical Electrochemical Corrosion Behavior of High-Nitrogen Austenitic Stainless Steel: Non-Pitting in Transpassivation
The transpassivation and pitting corrosion behavior of a high-nitrogen stainless steel (HNS), Fe18Cr15Mn3Mo0.92N, were systematically investigated by electrochemical analysis, morphology observation, and X-ray...
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Article
Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling
Reperfusion injury, which is distinct from ischaemic injury, occurs when blood flow is restored in previously ischaemic brain tissue, further compromising neurons and other cells and worsening the injury. Ther...
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Article
Enhanced Nitriding of 38CrMoAl Steels with Laser Vibrational Excitation of Ammonia
Gas nitriding is a thermochemical surface hardening process that is widely used in industry but suffers from a low decomposition rate of ammonia (NH3) and extremely long processing cycles. To enhance the gas nitr...
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Article
Open AccessInvestigating the impact of a large river and its surrounding contextual conditions on pedestrians’ summer thermal perceptions in a Cfa-climate city
Thermal comfort studies are usually employed to find subjective thermal responses [indicated by neutral temperature (NT), i.e. the temperature with no thermal stress] of residents from a region towards thermal...
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Article
Degradation of Bisphenols by Micro-Nano Bubbles Assisted Laccase: Kinetics, Michaelis–Menten Kinetics, Degradation Pathway, and Transformation Relationship
Bisphenols as an important industrial raw material has endocrine disruption, reproductive toxicity, and neurotoxicity. Laccase (Lac) has demonstrated excellent catalytic oxidation performance for phenolic comp...
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Article
Open AccessLarge-scale geographic patterns and environmental and anthropogenic drivers of wetland plant diversity in the Qinghai-Tibet Plateau
The geographic patterns of plant diversity in the Qinghai-Tibet Plateau (QTP) have been widely studied, but few studies have focused on wetland plants. This study quantified the geographic patterns of wetland ...
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Article
Open AccessCausal impact of DNA methylation on refracture in elderly individuals with osteoporosis – a prospective cohort study
Osteoporotic vertebral compression fractures (OVCF) in the elderly increase refracture risk post-surgery, leading to higher mortality rates. Genome-wide association studies (GWAS) have identified susceptibilit...
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Article
Electrical Performance of the Side Region in a Multi-crystalline Silicon Ingot
This paper investigates the impact of low minority carrier lifetime areas (red-zones) in multi-crystalline silicon ingots on cell efficiency. Wafers, sliced parallel to the sidewall, were analyzed using µ-PCD ...
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Article
Open AccessThe potent potential of MFAP2 in prognosis and immunotherapy of triple-negative breast cancer
Microfibril-associated protein 2 (MFAP2) is a protein presenting in the extracellular matrix that governs the activity of microfibrils through its interaction with fibrillin. While the involvement of MFAP2 in ...
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Article
Characteristics and Risk Factors for Pediatric Sepsis
Sepsis is considered a major cause of health loss in children and had high mortality and morbidity. Currently, there is no reliable model for predicting the prognosis of pediatric patients with sepsis. This st...
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Article
Acetylene/argon mixture plasma to build ultrathin carbon bridge of CFx/C/MnO2 for high-rate lithium primary battery
Forming an ultrathin conducting layer on a fluorinated carbon (CFx) surface for reducing severe electrochemical polarization in lithium/fluorinated carbon primary batteries (Li/CFx) remains a considerable challen...
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Article
Open AccessElectroacupuncture attenuates neuropathic pain via suppressing BIP-IRE-1α-mediated endoplasmic reticulum stress in the anterior cingulate cortex
Studies have suggested that endoplasmic reticulum stress (ERS) is involved in neurological dysfunction and that electroacupuncture (EA) attenuates neuropathic pain (NP) via undefined pathways. However, the rol...
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Article
Trace Pd alloyed with Au to boost Au/uncalcined TS-1 catalyzed propane hydro-oxidation to acetone
Selective oxidation of propane to acetone (AC) with H2 and O2 provides a direct route to convert low-cost propane into value-added products. Unfortunately, the catalytic activity of conventional Au/Ti-based catal...
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Article
GPC3-targeted CAR-T cells expressing GLUT1 or AGK exhibit enhanced antitumor activity against hepatocellular carcinoma
Chimeric antigen receptor-expressing T (CAR-T) cells induce robust antitumor responses in patients with hematologic malignancies. However, CAR-T cells exhibit only limited efficacy against solid tumors such as...
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Article
Data-driven sustainability evaluation and manufacturing system enhancement from economic, environmental, social, and sustainability perspectives
Sustainable manufacturing is crucial to achieving carbon neutrality targets. However, research on the sustainability of manufacturing systems is limited, and high consumption, low efficiency, and high emission...
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Article
Cerebrospinal Fluid from Patients After Craniotomy with the Appearance of Interleukin-6 Storm Can Activate Microglia to Damage the Hypothalamic Neurons in Mice
We monitored CSF (cerebrospinal fluid) for Th1/Th2 inflammatory cytokines in a patient with unexplained postoperative disturbance of consciousness after craniotomy and found that the level of IL-6 (interleukin...
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Article
Azobenzene-based ultrathin peptoid nanoribbons for the potential on highly efficient artificial light-harvesting
The development of artificial light-harvesting systems based on long-range ordered ultrathin organic nanomaterials (i.e., below 3 nm), which were assembled from stimuli-responsive sequence-controlled biomimetic p...
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Article
Evaluation of transmission risk of respiratory particles under different ventilation strategies in an elevator
People in elevators are at risk of respiratory infection because the elevator cabin is crowded and has poor ventilation. The exhaled particles may be inhaled by the susceptible person, deposited on the surface...
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Article
IRE1α: from the function to the potential therapeutic target in atherosclerosis
Inositol requiring enzyme 1 (IRE1) is generally thought to control the most conserved pathway in the unfolded protein response (UPR). Two isoforms of IRE1, IRE1α and IRE1β, have been reported in mammals. IRE1α...
