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Article
Open AccessSelective production of methylindan and tetralin with xylose or hemicellulose
Indan and tetralin are widely used as fuel additives and the intermediates in the manufacture of thermal-stable jet fuel, many chemicals, medicines, and shockproof agents for rubber industry. Herein, we disclo...
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Article
Open AccessOsteocyte mitochondria regulate angiogenesis of transcortical vessels
Transcortical vessels (TCVs) provide effective communication between bone marrow vascular system and external circulation. Although osteocytes are in close contact with them, it is not clear whether osteocytes...
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Article
Open AccessImproved adaptive regularization for simulated annealing inversion of transient electromagnetic
Geophysical inversion usually involves ill-posed problem. Regularization is the most commonly used method to mitigate this problem. There are many regularization parameter selection methods, among which the ad...
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Article
Open AccessMolecular classification reveals the sensitivity of lung adenocarcinoma to radiotherapy and immunotherapy: multi-omics clustering based on similarity network fusion
Due to individual differences in tumors and immune systems, the response rate to immunotherapy is low in lung adenocarcinoma (LUAD) patients. Combinations with other therapeutic strategies improve the efficacy...
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Article
Open AccessEffects of Pilates exercises on spine deformities and posture: a systematic review
Pilates is becoming increasingly popular amongst a wide range of people and is gaining more attention. It is also an effective means of physical rehabilitation. The aim of this systematic review is to explore ...
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Article
Open AccessCharacteristics and outcome of patients with left atrial appendage closure in China: a single-center experience
Clinical characteristics and long-term data on the safety and efficacy of LAAC in preventing cerebrovascular accident and thromboembolism among Chinese patients with non-valvular AF (NVAF) remain limited.
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Article
Open AccessL-serine combined with carboxymethyl chitosan guides amorphous calcium phosphate to remineralize enamel
The aim of this study is to investigate a robust and stable calcium-phosphorus system to remineralize human early enamel caries lesions with nanocomplexes of carboxymethyl chitosan/L-serine/amorphous calcium p...
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Article
Open AccessAngle Measurement Based on Second Harmonic Generation Using Artificial Neural Network
This article proposed an angle measurement method based on second harmonic generation (SHG) using an artificial neural network (ANN). The method comprises three sequential parts: SHG spectrum collection, data ...
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Article
Open AccessCan “In–Out–In” posterosuperior screws meet nutrient foramina in patients with femoral neck fractures?
The “In–Out–In” (IOI) posterosuperior screw was common in screw fixations of femoral neck fractures. The impacts of the IOI screw on the blood supply of the femoral head have not yet been clarified. The nutrie...
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Article
Open AccessCompact optical convolution processing unit based on multimode interference
Convolutional neural networks are an important category of deep learning, currently facing the limitations of electrical frequency and memory access time in massive data processing. Optical computing has been ...
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Article
Open AccessKnowledge, attitude, and practice of nephrologists on the decision for renal replacement therapy
This study aimed to investigate the Knowledge, Attitude, and Practice (KAP) of nephrologists on the decision of renal replacement therapy (RRT), including peritoneal dialysis, hemodialysis, and kidney transpla...
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Article
Open AccessEnvironmental-friendly regenerated lignocellulose functionalized cotton fabric to prepare multi-functional degradable membrane for efficient oil–water separation and solar seawater desalination
Freshwater pollution and shortage have become an imminent problem. Therefore, it is necessary to develop a multi-functional membrane for the production of fresh water. In this work, the regenerated lignocellul...
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Article
Open AccessTumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing
Immunotherapy has revolutionized cancer treatment, but most patients are refractory to immunotherapy or acquire resistance, with the underlying mechanisms remaining to be explored.
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Article
Open AccessThe ferroptosis signature predicts the prognosis and immune microenvironment of nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is a cancer with a high metastatic rate and poor prognosis. Growing studies suggest that ferroptosis take part in the development of tumours. At the same time, the connection bet...
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Article
Open AccessLyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2
Advanced mRNA vaccines play vital roles against SARS-CoV-2. However, most current mRNA delivery platforms need to be stored at −20 °C or −70 °C due to their poor stability, which severely restricts their avail...
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Article
Open AccessSAMHD1 silencing cooperates with radiotherapy to enhance anti-tumor immunity through IFI16-STING pathway in lung adenocarcinoma
Sterile alpha motif domain and histidine-aspartate domain-containing protein 1 (SAMHD1) is a DNA end resection factor, which is involved in DNA damage repair and innate immunity. However, the role of SAMHD1 in...
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Article
Open AccessOverexpression of lncRNA HOXA-AS2 promotes the progression of oral squamous cell carcinoma by mediating SNX5 expression
Oral squamous cell carcinoma (OSCC) is one of the most common head and neck cancers. Long non-coding RNA HOXA-AS2 (lncRNA HOXA-AS2) have been extensively studied in various cancers. However, the expression and...
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Article
Open AccessPrediction of radiosensitivity and radiocurability using a novel supervised artificial neural network
Radiotherapy has been widely used to treat various cancers, but its efficacy depends on the individual involved. Traditional gene-based machine-learning models have been widely used to predict radiosensitivity...
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Article
Open AccessMicroRNA-223 negatively regulates the osteogenic differentiation of periodontal ligament derived cells by directly targeting growth factor receptors
MicroRNA (miRNA) is accepted as a critical regulator of cell differentiation. However, whether microRNA-223 (miR-223) could affect the osteogenic differentiation of periodontal ligament (PDL)-derived cells is ...
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Article
Open AccessComparative profiling of single-cell transcriptome reveals heterogeneity of tumor microenvironment between solid and acinar lung adenocarcinoma
The diversity of histologic composition reflects the inter- and intra-tumor heterogeneity of lung adenocarcinomas (LUADs) macroscopically. Insights into the oncological characteristics and tumor microenvironme...
